#stemcells researcher | Director of Cell Processing Facility @umontpellier @CHU_Montpellier | #iPScells #lung | @stemgenomics

Joined July 2009
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📢 Les inscriptions au Diplôme Universitaire « Thérapies Cellulaire & Génique – Médecine Régénératrice » sont ouvertes! 📅 Formation intensive du 9 au 20 novembre 2026 💻 Accessible en présentiel ou en distanciel 😀 Inscriptions : buff.ly/5jebkp6
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CAR T-cell therapy is able to deplete anti-HLA antibodies. Combining CAR T cells directed against CD19 and against BCMA resulted in successful kidney transplantation in two highly sensitized patients. nejm.org/doi/pdf/10.1056/NEJ…
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John De Vos retweeted
I am sending an open letter to Thermo Fisher. Their response to my response to their manipulated western blot is bullying and petty. Yes, this western blot really is manipulated, it is unfair on me to say otherwise. I don't make those accusations lightly. #ThermoFishy
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A very impressive study for how we could prevent lung cancer more than 5 years before it is diagnosed. Using machine learning, discovery of a 14-plasma protein signature of risk that predicts responsiveness to an antibody therapy to interleukin, IL-1β Validated across 8 cohorts @CellCellPress @CharlesSwanton cell.com/cell/fulltext/S0092…
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KINSHASA, June 5 (Reuters) - Democratic Republic of Congo said on Friday that 71 new Ebola cases were confirmed in a 24-hour ​period and warned of rapid community transmission of the deadly ‌disease.
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The longevity (aka rejuvenation) companies focused on partial cellular reprogramming are getting more investments and starting clinical trials (eye and liver) @newlimit gets a new jolt, to add to billions invested in @altos_labs, @RetroBio_ , @lifebiosciences, @turn_bio, @ShiftBioscience, @rejuvenatebio, youthbiotx.com
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The liver, and some of its immune cells (super magnetic macrophages), as a sensory organ for pigeons!
How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers in Science have now identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. Learn more: scim.ag/3Qfbcfl
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John De Vos retweeted
New article in @PNASNews: We all know that ChatGPT loves to delve, bolster, leverage, encompass, showcase, underscore, et cetera. I analyzed full text of 7.3 million journal articles published 2020-2025, hunting for 228 words that spiked after ChatGPT launched in late 2022.
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China Focus: First combined pig liver, kidney transplant in human marks milestone in organ shortage fight english.news.cn/20260601/012…
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Successful epicardial transplantation of an engineered heart muscle derived from allogeneic #iPSCells in patients with heart failure and reduced left ventricular ejection fraction, demonstrating the potential of cardiac remuscularization therapy. nejm.org/doi/full/10.1056/NE…
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"We've arranged a society based on science and technology, in which nobody understands anything about science and technology. And this combustible mixture of ignorance and power, sooner or later, is going to blow up in our faces."
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May 30
Two economists just published a mathematical proof that AI will destroy the economy. Not might. Not could. Will — if nothing changes. The paper is called "The AI Layoff Trap." Published March 2, 2026. Wharton School, University of Pennsylvania. Boston University. Peer reviewed. Mathematically modeled. The conclusion is one sentence. "At the limit, firms automate their way to boundless productivity and zero demand." An economy that produces everything. And sells it to nobody. Here is how you get there. A company fires 500 workers and replaces them with AI. A competitor fires 700 to keep up. Another fires 1,000. Every company is behaving rationally. Every company is following the incentives correctly. And every company is building a trap for itself. Because the workers who were fired were also customers. When they lose their jobs faster than the economy can absorb them, they stop spending. Consumer demand falls. Companies respond by cutting costs — which means automating more workers — which means less spending — which means more falling demand — which means more automation. The loop has no natural exit. The researchers tested every proposed solution. Universal basic income. Capital income taxes. Worker equity participation. Upskilling programs. Corporate coordination agreements. Every single one failed in the model. The only intervention that worked: a Pigouvian automation tax — a per-task levy charged every time a company replaces a human with AI, forcing them to price in the demand they are destroying before they pull the trigger. No government has implemented this. No major economy is seriously discussing it. Meanwhile the numbers are already tracking the curve. 100,000 tech workers laid off in 2025. 92,000 more in the first months of 2026. Jack Dorsey fired half of Block's workforce and said publicly: "Within the next year, the majority of companies will reach the same conclusion." Nobody is doing anything wrong. Companies are following their incentives perfectly. That is exactly the problem. Rational behavior. At scale. Simultaneously. With no mechanism to stop it. Two economists built the math. The math leads to one place. Source: Falk & Tsoukalas · Wharton School Boston University ·
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Cardiac "remuscularization" for treating severe heart failure with patched heart muscle derived from stem cells (a biological ventricular assist device) successful in 12 of 20 patients @NEJM nejm.org/doi/full/10.1056/NE… nejm.org/doi/full/10.1056/NE…
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May 27
Deepak Srivastava, MD, describes the scientific foundations of a phase 1–2 study of stem-cell–derived ventricular assist tissue transplanted onto the epicardial surface of failing human hearts. Learn more about the science behind the study in the editorial “Remuscularizing the Failing Human Heart,” from @GladstoneInst and @ucsf: nej.md/4o0ViBS
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Nature-based interventions are good for your health. A new systematic assessment (and they are free) nature.com/articles/s41562-0…
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🧬 Envie de vous former aux thérapies cellulaires, géniques et à la médecine régénératrice ? Le DU de la Faculté de Médecine de Montpellier revient du 9 au 20 novembre 2026, en présentiel ou distantiel 😀. Inscription et programme: buff.ly/qhKJV8X
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John De Vos retweeted
De nouveau, la France vient de vivre sa journée de mai la plus chaude jamais observée à l’échelle nationale (et ce record sera probablement déjà battu demain). Du 22 au 26 mai, le nombre de records mensuels de chaleur battus ou égalés a explosé : 19, puis 60, 120, 353 et enfin 402 records en une seule journée. Au total, cela représente 954 records mensuels en cinq jours seulement, confirmant le caractère totalement inédit de cet épisode, toutes saisons confondues. Grâce à l’exceptionnel travail de dataclimat.fr, permettant de lutter contre la désinformation climatique, il est possible de filtrer uniquement les stations disposant de plus de 50 ans de mesures et d’une qualité d’installation jugée bonne à excellente. Dans cette catégorie d’excellence scientifique, 130 stations ont déjà battu leur record absolu de chaleur pour un mois de mai en 2026. Le constat est implacable : en seulement 10 ans, 1548 records de chaleur ont été battus contre seulement 72 records de froid. Trois conclusions s’imposent : ➡️Nous ne retrouverons jamais le climat de notre naissance. ➡️Battre des records de chaleur est devenu tristement banal. ➡️Avec 96 % des records orientés vers la chaleur, ce déséquilibre massif constitue l’une des signatures les plus nettes du changement climatique.
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