DNA repair & topoisomerases • Feminist
Joined February 2012
- Tweets 1,382
- Following 891
- Followers 317
- Likes 1,414
19 Photos and videos
Almudena Serrano-Benítez retweeted
5 Mar 2025
🚨 Fully funded #PhD opportunity! 🚨
Passionate about cancer research? Join @MadziaCrossley's team to investigate how R-loop dysregulation contributes to cancer.
📍 Cambridge, UK
💰 Fully funded
📅 Apply by 24 March 2025
cruk.cam.ac.uk/vacancies/phd…
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Almudena Serrano-Benítez retweeted
8 Jan 2025
Happy to share our newly published article in Nature Communications! In this work, we uncover the novel role of KLF5 in sensitizing cells to ATR inhibition, identifying it as a synthetic lethal partner with the tumor suppressor ARID1A. @SPJacksonGroup
nature.com/articles/s41467-0…
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Almudena Serrano-Benítez retweeted
26 Nov 2024
Now out in @GenomeMedicine @BioMedCentral. Transform your #crispr screens with "Exorcise", EXOme-guided Re-annotation of nuCleotIde SEquences, doi.org/10.1186/s13073-024-0….
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Almudena Serrano-Benítez retweeted
12 Nov 2024
Genome engineering excelled at small nucleotide changes, but large edits remained challenging. Recent innovations are changing this.
We reviewed the field of structural variant engineering @NatureGenet 🧬
@JulianeWeller @TVanderstichele @LeopoldParts
nature.com/articles/s41588-0…
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Almudena Serrano-Benítez retweeted
12 Nov 2024
Transcriptome-scale RNA-targeting CRISPR screens
reveal essential lncRNAs in human cells
cell.com/cell/fulltext/S0092…
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Almudena Serrano-Benítez retweeted
3 Nov 2024
las temporeras y temporeros de huelva también necesitan ayuda. sus chabolas se han destrozado
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Almudena Serrano-Benítez retweeted
17 Oct 2024
Always a treat to catch up with @SPJacksonGroup alumni. And an opportunity to hear about the latest breakthroughs in the DDR field @EMBO meeting, #EMBOdnaDamage24
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Almudena Serrano-Benítez retweeted
5 Oct 2024
Epitranscriptome in action: RNA modifications in the DNA damage response: Molecular Cell cell.com/molecular-cell/full…
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Almudena Serrano-Benítez retweeted
23 Sep 2024
Thrilled to see our work on murine oesophageal #Epithelioids published in @NatureGenet, after many years of hard work alongside @AlbertHerms during our postdoc at Phil Jones' lab @Sangerinstitute and built on the foundational work by @MariaPAlcolea
nature.com/articles/s41588-0…
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The @duxin_lab , with @NilssonLabCph, uncover #PolK's dual roles in #DNAdamage bypass. Using #CRISPR & #Xenopuseggextracts, they show PolK’s catalytic & non-catalytic functions -repairing minor groove lesions and aiding Polζ in overcoming #chemotherapeutic-induced DNA lesions!⬇️
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Almudena Serrano-Benítez retweeted
6 Sep 2024
Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors! science.org/doi/10.1126/scie…
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Almudena Serrano-Benítez retweeted
5 Sep 2024
Our latest paper -> On identifying the mutations driving clonal hematopoiesis using machine learning models - BoostDM-CH
Great team work by @SantiDemajo, @JoanEenric, @fmuinos et al
Tweetorial 👇
5 Sep 2024
‼️ The final version of our article “Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis” is out in Cancer Discovery @CD_AACR: aacrjournals.org/cancerdisco…
Learn more about our findings in this thread 👇🏽
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Almudena Serrano-Benítez retweeted
5 Sep 2024
Excited to share our new preprint, led by our @GiuseppinaDAle9 and Olga Kochenova @harvardmed, a great collaborative effort with Johannes Walter's lab, @GS_Lab_Bham.
USP37 prevents premature disassembly of stressed replisomes by TRAIP biorxiv.org/content/10.1101/…
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Almudena Serrano-Benítez retweeted
4 Sep 2024
Thrilled to share my lab’s latest work, out recently in Mol Cell, on a role for HLTF in G4 resolution. Led by the amazing Gongshi Bai with essential contributions from @davidcortez, Brandt Eichman, @CejkaLab and @BoultonLab. See: authors.elsevier.com/a/1jbBg…
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Almudena Serrano-Benítez retweeted
3 Sep 2024
Excited to share our lab's latest research, out today @NatureSMB, which describes how 53BP1 controls DNA Repair in class-switching B cells & BRCA1 mutant cancers. Final article can be found here:
nature.com/articles/s41594-0…; & the following thread walks you through the details
31 Dec 2023
Our lab's latest is now out on BioRxiv. In this work we set out to understand how 'shieldin' regulates #DNArepair, focusing on its physiological function in B cells & pathological contributions to BRCA1-mutant cancers. Some background & take-home msgs (1/) biorxiv.org/content/10.1101/…
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Almudena Serrano-Benítez retweeted
30 Aug 2024
Many thanks to the @MRC_LMB (the people & their science) & @UKRI_News for this amazing unbelievable opportunity. I'm ecstatic beyond measure. It's a bit intimidating to be in such a great place full of groundbreaking minds but hope I can contribute with my share to new research!
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Almudena Serrano-Benítez retweeted
23 Aug 2024
RAD51 protects abasic sites to prevent replication fork breakage dlvr.it/TCHxrp
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Almudena Serrano-Benítez retweeted
25 Aug 2024
Esto es El Congo.
Esto son las minas para extraer los minerales para que occidente tenga progreso.
Es una mina que ha colapsado, debido a la manera infrahumana en la que trabajan, muchos son niños.
Después cuando huyen de sus países,no los quieren aquí.
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Almudena Serrano-Benítez retweeted
21 Aug 2024
Online Now: RNA interacts with topoisomerase I to adjust DNA topology dlvr.it/TCBkDV
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