Neuroproteomics, mass spectrometry, PTMs & protein complexes.

Joined April 2017
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Collins lab retweeted
Just look at how the rate of increase in life expectancy has been dropping in this country. And it’s not just since COVID/2020. The decline seemed to start around 2010… weird, that.
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Collins lab retweeted
🚨New analysis from @royalsociety UK visa costs for researchers: 🫣 21x higher than France (Talent passport for researchers) 😱34x higher than Germany (Scientific visa) 😬Have increased by 126% since 2019 while other countries have made theirs cheaper royalsociety.org/news-resour…
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Collins lab retweeted
24 May 2024
You know those times when you come out of a theater and just know that film would win Best Picture…this is the human genetics equivalent. I’m not prone to hyperbole but cannot remember the last time I was this impressed by a genetics manuscript. Congratulations!
Excited to share this discovery: Huntington's disease is a DNA process for almost all of a cell's life. Inherited HD alleles are innocuous, just unstable – CAG repeats slowy expand throughout life, acquiring toxicity only when quite long (>150 CAGs). biorxiv.org/content/10.1101/…
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Collins lab retweeted
Congratulations to @bmss_official , @PerditaB and everyone involved in making this possible! A much needed investment into UK's mass spectrometry infrastructure. Thank you, @The_MRC @UKRI_News !
£49.35m to support the Critical Mass UK (C-MASS) project, co-delivered with @EPSRC, that will develop a UK-wide hub-and-spoke infrastructure to advance our capability in mass spectrometry.
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Collins lab retweeted
Congrats - an incredible resource!
Very happy to share our extensive and systematic Phosphoproteomic Stress Signaling Atlas that is now published @NatureSMB: rdcu.be/doHAL Thanks to the @juditvr lab and co-autors @AnthonyBarente , Noelle Fukuda & @RRodriguezMias! #proteomics #signaling #TeamMassSpec /1
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Collins lab retweeted
A BBSRC-funded PhD position is available to investigate how plants shape stress memories. With Mark Collins and @Katherine_Denby. Please RT and spread the news! For further details, check FindAPhD: findaphd.com/phds/project/wh…
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Collins lab retweeted
Phosphorylation based signalling is still quite understudied despite a general perception that it is well understood. A great study here measuring specificity for human serine/threonine kinases nature.com/articles/s41586-0…

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Collins lab retweeted
So sad to hear the news of the passing of my mnd hero Doddie Weir. I'm sorry to say, how many more warriors die before this stupid government give the 50m they said they would give. I'm absolutely gutted to see my friendly giraffe die. You are the reason for being so positive RIP
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Collins lab retweeted
We have several new lectureships available! Sheffield is a great place to live, work and do science. If you or anyone you know want to join us, please get in touch! Please retweet.
Join us in Molecular and Cellular Biology @MCB_Sheffield! New lectureships available in the School of Biosciences, @ScienceShef @sheffielduni Deadline: 19th December 2022 More details here: jobs.ac.uk/job/CUV141/lectur… #academicjobs #lectureship #Sheffield (1/5)
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Great work Mohamed!
We are very excited to share our latest work that we released on BioRxiv today. Check it out: biorxiv.org/cgi/content/shor… #ICSA #HELSI #AcademicChatter #senescence #hostpathogeninteactions @MCB_Sheffield @collins_lab @melghazaly96
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Collins lab retweeted
Dear @BorisJohnson, I hear Rwanda is a lovely place to spend your retirement. Ken
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Collins lab retweeted
Our paper on sgRNA profiling of #SARSCov2 @nanopore @NetworkArtic genomes using periscope showing lineage specific changes is finally out! We find a striking increase in sgRNA abundance in B.1.1.7 infections and a potential sgRNA for ORF9b! 💥 nature.com/articles/s42003-0… short 🧵1/3

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Collins lab retweeted
#JBCMethodsMadness Championship is tomorrow at 12:00 p.m. ET! #TeamMassSpec vs. #TeamCryo 🟦🟨Be there or be square🟨🟦
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Collins lab retweeted
#OpenCell – Proteome-scale measurements of human protein interactions and localization is now published in @ScienceMagazine. In collaboration with the @czbiohub we leverage #CRISPR technology and combine ultra-sensitive #proteomics with confocal imaging. science.org/doi/10.1126/scie…
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Collins lab retweeted
I would like to thank many friends and colleagues for messages of support on the first day of Russian invasion of #Ukraine! For those, who would like to contribute to the humanitarian effort, please consider donating to @BritishRedCross: donate.redcross.org.uk/appea…

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Collins lab retweeted
DHHC enzymes catalyze protein palmitoylation in thousands of substrates. We used a combination of crystallography, computational simulations and biochemistry to present the first structure of a precatalytic complex of human DHHC20 with palmitoyl CoA. pnas.org/content/119/7/e2022…
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Collins lab retweeted
Proteomics neurobiology are powerful combo! Here we describe a multimodal (APEX, APMS) and dynamic (stimulation, mutants) PPI analysis for tau that enhances our understanding of both tau molecular biology as well as clinical protein profiles from AD patients.
20 Jan 2022
We’re excited to share our latest research out in @CellCellPress TODAY! Using APEX and AP-MS proteomics, we mapped Tau interactomes that were modified by neuronal activity and FTD mutations in hiPSC-derived neurons. Check it out👉sciencedirect.com/science/ar…
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Collins lab retweeted
“Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants” by Eunju Shin et al. Nature Communications nature.com/articles/s41467-0…
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