🚨 PROTEUS: perioperative apalutamide moves into high-risk localized #prostatecancer
Just out in @NEJM
🧬 2109 men w/ high-risk localized or locally advanced PCa randomized to ADT apalutamide vs ADT placebo around radical prostatectomy.
🎯 Both stated primary endpoints met.
⚠️ But the trial deserves nuance. Thread 🧵
#ASCO26@ASCO@PCF_Science
RAS finally getting drugged is one of the great stories in modern biology, and almost nobody outside oncology understands why it's such a big deal.
YOU'LL LEARN SOMETHING AWESOME TODAY.
i am going to keep this as understandable (and simple) as i can.
OPEN THE THREAD.
🧵
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
The FDA approves the signatera ctDNA assay for muscle invasive bladder cancer patients post surgery.
This is based on the results of Imvigor011 study (atezo vs placebo in ctDNA positives, surveillance for the ctDNA negatives).
It opens a new chapter for personalised therapy in urothelial cancer. Focusing on early treatment for those patients that need it and sparing those at lower risk potentially harmful treatment makes sense.
‘It is the first companion diagnostic approval in the field of blood-based MRD.’
natera.com/company/news/sign…
We recently got a brand spanking🔎🔎 new @PhotocureASA Blue 💙 light system @CleClinicUro and I am slowly convincing 1 resident at a time the incredible value in #bladdercancer starting w/ @eiftu
We recently got a brand spanking🔎🔎 new @PhotocureASA Blue 💙 light system @CleClinicUro and I am slowly convincing 1 resident at a time the incredible value in #bladdercancer starting w/ @eiftu
Force of nature #hadleywood giving the #WomenofGURS lecture at @SocietyGURS Congress, sharing her experiences and incredible insights. Lucky to call her a colleague, mentor and friend 🤍
@mdewittfoy
It is harder than ever to believe in our democracy. It has been attacked by billionaires and hollowed out by its failure to respond to working peoples’ struggles.
But on this campaign, we dreamed of a new day. And we have won it together.