📌 Superscan 🦴 (Bone Scan / PET)
🔍 Definition: Diffuse, intense skeletal uptake with ↓/absent renal & soft tissue activity.
🧠 Causes:
1️⃣ Metastatic disease → prostate ♂️, breast 🩷, lung 🌬️
2️⃣ Metabolic bone disease → hyperparathyroidism 🦋, renal osteodystrophy 🩺
3️⃣ Paget’s disease 🏗️
4️⃣ Myeloproliferative / marrow infiltration (myelofibrosis, lymphoma) 🩸
🛠 Clues:
•Uniform skeletal uptake
•Loss of normal renal visualization (tracer “locked” in bone)
•Correlate with clinical & labs (Ca, ALP, PSA, tumor markers)
💊 Management:
•Treat underlying cause 🎯 (e.g., hormonal therapy for prostate CA, chemo for metastases, manage hyperparathyroidism)
•Supportive: pain control 💊, bone protection (bisphosphonates/denosumab) 🦴
•Monitor response with tumor markers & follow-up imaging 📈
💡 Exam Pearl: In cancer pts, superscan = widespread bone mets until proven otherwise; in renal pts, think metabolic bone disease.
#Hematology #Oncology #Superscan #BoneScan #PETCT #ExamPearls