Stage II & III Colon Cancer Management – 2026 Guideline-Based Summary 🔥 Completely updated visual guide incorporating the latest NCCN v2.2026, ESMO Express Update & ATOMIC trial results: • Adjuvant atezolizumab chemo is now standard for Stage III dMMR/MSI-H • Structured exercise program (ESMO 2026) recommended post-treatment • ctDNA as emerging prognostic tool • DPYD testing & PIK3CA/aspirin notes added One-page, high-yield reference for trainees & practicing oncologists. Save it. Share it. Use it. #ColonCancer #Oncology #CancerGuidelines #MedicalEducation Follow for more evidence-based visuals → @DrRupamOncology

📊 GEJ Carcinoma (Gastroesophageal Junction) – Full Guideline-Based Management at a Glance! Most GEJ adenocarcinomas are treated like esophageal or gastric cancer depending on Siewert type & stage. This one-pager covers: • Initial workup & essential biomarkers (HER2, PD-L1 CPS, MSI/dMMR, CLDN18.2, NGS) • Perioperative FLOT now preferred (superior OS vs CROSS per ESOPEC) • CROSS as alternative for bulky/borderline disease • Adjuvant nivolumab (CheckMate-577) after CROSS if residual disease • Biomarker-driven therapy in metastatic & unresectable settings • High-yield clinical pearls Perfect quick reference for fellows, residents & practicing oncologists! 🔖 Save | Share | Tag a colleague Made with ❤️ by Dr Rupam Manna Follow for more Cancer Concepts Explained → @DrRupamOncology #GEJCancer #EsophagealCancer #GastricCancer #Oncology #MedTwitter #CancerGuidelines #FLOT #Immunotherapy

🚨 New standard of care in resected EGFR-mutated NSCLC! Adjuvant Osimertinib for 3 years after complete resection of stage IB–IIIA EGFR (Ex19del or L858R) non-metastatic lung cancer is now Category 1 recommended by NCCN, ESMO & ASCO. From the practice-changing ADAURA trial: • DFS at 24 months: 89% vs 53% • Risk of recurrence or death reduced by ~80% (HR 0.20) Beautifully summarized by @DrRupamOncology — perfect quick-reference for oncologists, thoracic surgeons & residents. Early EGFR testing adjuvant TKI = game changer for never-smokers & Asian patients too. Save this post ⬇️ Share with your team! #NSCLC #EGFR #Osimertinib #LungCancer #ADAURA #AdjuvantTherapy #Oncology #MedEd #CancerGuidelines

🧬 Papillary Thyroid Carcinoma (PTC) – Fully Updated 2025 ATA Guideline Summary Brand-new version by @DrRupamOncology now incorporating the latest 2025 ATA Guidelines! Everything you need in one beautiful page: • Initial evaluation & Bethesda system • Surgical management (stronger lobectomy preference in low-risk) • New 4-tier dynamic risk stratification • Individualized TSH suppression based on response to therapy • RAI, follow-up, recurrence & systemic therapy PTC = 80–85% of thyroid cancers with excellent prognosis when managed with modern risk-adapted, de-escalated care. A must-have quick-reference for endocrinologists, endocrine surgeons, oncologists & residents! Save this post ⬇️ Share with your team! #ThyroidCancer #PTC #ATA2025 #Endocrinology #Oncology #MedEd #ThyroidSurgery #CancerGuidelines

Clinical question: For cT2N0 esophageal cancer, should we proceed with primary surgery or start with neoadjuvant therapy? Our collective effort through the @ISDE_net to address this clinical dilemma is now published. Key takeaways: • Neoadjuvant therapy → surgery is suggested for most patients • Clinical staging is imperfect, with nodal upstaging reported in up to ~48% • Primary surgery may still be appropriate for carefully selected low-risk tumors Overall, the guidance aligns with the @NCCN guidelines many cT2 tumors. The challenge now is better risk stratification and staging to identify who truly benefits from neoadjuvant therapy. @MiamiCancerInst @BHCancerCare @BaptistHealthSF @SocSurgOnc @OncUpdates @OncBrothers #EsophagealCancer #GIOncology #CancerGuidelines #PrecisionOncology academic.oup.com/dote/articl…

Precision oncology in stage IV NSCLC is no longer optional. It is the backbone of care. 🧬🫁 One diagnosis. Multiple molecular roads. Very different treatments. What matters first? Broad NGS upfront. Always. 🔹 EGFR alterations Exon 19 del / L858R: osimertinib ± chemo or amivantamab lazertinib Exon 20 insertions: chemo amivantamab Resistance pathways now include MET, T790M, ADCs, bispecifics 🔹 ALK, ROS1, RET, METex14, BRAF V600E, NTRK Highly effective targeted TKIs upfront Sequencing matters more than ever after progression 🔹 KRAS G12C, HER2 exon 20, NRG1 Targeted options mainly in later lines ADCs and next-gen TKIs changing outcomes Key takeaway 👇 Stage IV NSCLC is not one disease. Treat the driver, not just the histology. 📌 Broad molecular testing at diagnosis = survival-defining decision. #OncoTwitter #MedTwitter #LungCancer #NSCLC #PrecisionOncology #TargetedTherapy #CancerGuidelines @asco @JCO_ASCO @myESMO @OncoAlert

👉 Join us for the #ESMOGuidelines webinar to get practical insights on ctDNA, NGS, MSI‑H/dMMR and targeted treatments to support personalised #CRC care. Open to all ESMO account holders. 🔗Register here: ow.ly/qaVF50Y1LhQ #ESMOWebinar #ESMOOnAir #CancerGuidelines

💫 #ONCOnews 💫 🚨BREAKING: NCCN SCLC Guidelines now include Lambert-Eaton Myasthenic Syndrome (LEMS) 🫁 📌 VGCC antibody testing neuro consult to diagnose LEMS ✅ Amifampridine may be considered for supportive care 📈 Boosts awareness & adoption of VGCC testing & treatment 🔗 Read more: bit.ly/3J7L4PI #OncoAlert #OncEd #Oncology #CancerGuidelines #LungCancer

🧠New NCI Guidelines Alert Just released updated treatment #guidelines for adult central nervous system #tumors 📄 Read more: NCI CNS Tumors Treatment Guidelines #NeuroOncology #BrainTumor #CancerGuidelines #radonc #radiotherapy #brain

I will start to occasionally share on X breakthroughs at Natera (NTRA) and my other companies that I hope you will find interesting and inspiring. @NateraGenetics has generated over 200 peer-reviewed papers and some transformations in healthcare. The latest is in #CancerCare: Simultaneous papers in Nature Medicine and Annals of Oncology released data from the Circulate Japan Trial. Results show a 10x overall survival improvement for Signatera-positive vs. negative colorectal cancer (CRC) patients and that we can at last decipher who should and shouldn’t receive chemotherapy after tumor removal. This technology can potentially save the US healthcare system more than any single drug repricing in the Inflation Reduction Act and save many patients the side-effect and emotional burden of unnecessary chemo. This already led to updates in the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines, marking a significant shift in global care. Congrats and thanks to the superb team at Natera; we’ve surpassed 85 publications on Signatera alone. Follow me here for updates. natera.com/company/news/nate… #ColorectalCancer #CancerResearch #CancerTreatment #HealthcareInnovation #CancerGuidelines #MedTech #Natera

Really sad to miss this !! Thanks @IvanD_Florez for amazing sessions this last year ! #cancerguidelines

I, editor of this special edition on imaging guidelines in oncology, along with my associate editors @DrNiveditaC and @jinita_10, hv brought forth 2 issues. Thank U @PadmajKulkarni5 @seemagulia1 @IJMPOofficial thieme-connect.de/products/e… @OncologyCompass @OncoAlert #cancerguidelines

#journalclub #bmus is upon us tomorrow!! Please join us - such a great article #MSK #cancerguidelines @SonoStephen @ReeveRuth @chynesSHU @UltrasoundPG @SCoRMembers please retreat and join for 1hr of CPD

Implementing the European Code of Cancer Practice to Improve Europe’s Cancer Outcomes Lets help bridge the gap between cancer guidelines and plans, and the everyday experience of patients and their carers - touchoncology.com/policy/jou… #cancer @EuropeanCancer #cancerguidelines

Have you heard about the recently completed and ongoing ESGO Guidelines projects? 👀Check out our Annual Update for 2020 to learn about the Guidelines Committee and our other initiatives! 👉 esgo.org/media/2021/03/ESGO-… #Cancerguidelines #gynaeonc

#cancerrehabilitation should be a standard in cancer care. #cancerguidelines recommend rehab for patients during treatment to help them keep up w/their daily activities. BUT current medical practice often falls short of including rehab in cancer care @WVUCancer @WVUPublicHealth

Νομίζω οτι ειναι φανερό . Ογκολόγοι που ΔΕΝ ακολουθούν τες κατευθυντήριες γραμμές έχουν χειρότερα αποτελέσματα ! #CancerGuidelines #KnowYourOncologist

Nuevo encuentro con los representantes de la @NCCN los doctores Robert Carlsson, Gery Weymuller y Jorge Bacigalupo, para avanzar en los proyectos de colaboración conjuntos #cancer #NCCN #CalidadONCO #CancerGuidelines 🇺🇸 Meeting with @NCCN to reach collaboration projects

Mencegah kanker paru!! Klik tautan ini untuk untuk mengetahui perkembangan tentang agen potensial terbaru untuk kemopreventif bit.ly/2UIGrNe #docquity #healthcare #cancer #cancerprevention #preventcancer #cancerguidelines #medicalguidelines

Should you start #colorectalcancer screening early? ow.ly/3QfR30o6ycg @AmericanCancer #cancerguidelines #coloncancerawareness