📢 The latest contribution from Dr. Massimo Mapelli(@MapelliMassimo ) and his team at IRCCS is now featured in RCM! Welcome to read this article 👉: imrpress.com/journal/RCM/26/… Article Highlights 💡 How do novel heart failure (HF) therapies impact functional capacity? This article synthesizes evidence on CPET metrics—VO₂ peak, VE/VCO₂ slope, OUES—across conventional drugs and emerging agents like ARNIs, SGLT2i, vericiguat, GLP-1 RAs, and finerenone. ✒️ Author: Nikita Baracchini, Teresa Maria Capovilla, Simona Costantino, Fiorella Puttini, Elisabetta Salvioni, Irene Mattavelli, Massimo Valenti, Emilia d'Elia, Elena Bertarelli, Piergiuseppe Agostoni, Gianfranco Sinagra, Massimo Mapelli 🏪 Affiliation: University of Trieste @UniTrieste; IRCCS; University of Milan; ASST Papa Giovanni XXIII Citation format: Nikita Baracchini, Teresa Maria Capovilla, Simona Costantino, Fiorella Puttini, Elisabetta Salvioni, Irene Mattavelli, Massimo Valenti, Emilia d'Elia, Elena Bertarelli, Piergiuseppe Agostoni, Gianfranco Sinagra, Massimo Mapelli. New Fuels for a Failing Engine: The Impact of Novel Heart Failure Drugs on Functional Capacity. Rev. Cardiovasc. Med. 2025, 26(9), 41919. doi.org/10.31083/RCM41919 📖 Don’t miss this citable reference for your future research! 👉Welcome to submit your work: imr.propub.com/ #HeartFailure #Cardiology #ExerciseCapacity #CPET #SGLT2i #ARNI #Vericiguat #MedicalResearch #RCMJournal #CardioScience #RCMPaper

📢 New Open Access Publication! 🔓 Peak oxygen uptake in older adults with heart failure: a systematic review and meta-analysis by Veronika Schmid & Mark J. Haykowsky et al. This study systematically reviews and quantifies evidence on peak oxygen uptake (VO₂peak) in older adults with heart failure, offering valuable insights into exercise capacity, prognosis, and rehabilitation strategies in this growing population. 🔗 Read the full article here: rdcu.be/eBtIM #heartfailure #VO2peak #exercisecapacity #aging #cardiachealth #OpenAccess

We know exercise capacity is a fundamental measure of cardiopulmonary fitness. Read our latest article reporting ILD patient outcomes stratified based on exercise status. #exercisecapacity #cardiopulmonaryfitness

🚨New Publication🚨 Exciting to share our recent study that could offer a novel and non-pharmacological approach to improving exercise capacity in pulmonary hypertension population. thorax.bmj.com/content/early… #PulmonaryHypertension #Thorax #ExerciseCapacity #NitrateSupplementation

👀📰#RCT on home exercise for #LungCancer patients after surgery: While it didn't improve self-report physical function, it ⬆️#ExerciseCapacity , #QOL & #SelfEfficacy up to 6 months! Program had high #PatientAdherence. Promising #HomeRecovery approach! ja.ma/4eZQTJ0

Does right ventricular function (RVF) shape recovery after transcatheter #mitralvalve intervention (TMVI)? Research shows TMVI boosts #ExerciseCapacity! Read more: bit.ly/HJC_TVMI @hjc_ed @tk_rudolph @VRudolph_HDZ #MitralRegirgitation #CardioTwitter #CPET #HeartHealth

#ArticlesInPress: YOUNG USERS OF ELECTRONIC CIGARETTES EXHIBIT REDUCED CARDIORESPIRATORY FITNESS Tijana Simovic, et al. ow.ly/oUVj50SBOCq #JAPPL #ExerciseCapacity #E-cigarettes

Can exercise help stable angina patients with low hemoglobin? Our latest case says YES! Improved #exercisecapacity & reduced #angina! researchgate.net/publication… #Cardiology #CardiacRehab #hemoglobin #exercisephysiology

In adults with #PulmonaryHypertension, low‐certainty evidence suggests #exercisebased #rehabilitation improves #exercisecapacity & #cardiopulmonaryhemodynamics. These programs also improve QoL (moderate‐certainty evidence) bit.ly/3uCU5sE @CochraneLibrary @CochraneNursing

We're looking for #Melbourne women over 55 years to take part in this study @erin_howden & @MonashUni to investigate if an approved #testosteronetherapy improves #exercisecapacity & #heartfunction in #postmenopausal women. Thanks @EmilyRice28 & #9News ➡️baker.edu.au/research/clinic…

Just published: #exercise initiated early during #COPD hospitalisation is safe and improves #exercisecapacity and #physicalfunction at hospital discharge. Work by our @CurtinAlliedHth Hons student Lynette Lai @Abbey_Sawyer1 @KylieHill2015 @warrp2 pubmed.ncbi.nlm.nih.gov/3830…

Long COVID's hidden toll: How does post-exertional malaise affect skeletal muscles? 🦠💪🔬 news-medical.net/news/202401… #LongCOVID #PostExertionalMalaise #SkeletalMuscle #ExerciseCapacity #Metabolic #Dysfunction #TissueAlterations #COVID19 #Pathology @NatureComms

🌟FREE Article of the Week🌟 Sympathetic neural overdrive and diminished exercise capacity in reduced ejection fraction heart failure related to anthracycline-based chemotherapy 🔓 ow.ly/ZYFl50Q4Fkt #Chemotherapy #ExerciseCapacity #HeartFailure

#ArticlesInPress, Does COVID-19 impair V̇O2peak in patients with cardiorespiratory disease? Insight from cardiopulmonary responses to maximal exercise pre- and post-illness Igor A. Fernandes, et al. ➡️ow.ly/Y1hR50PYIJQ #JAPPL #COVID19 #ExerciseCapacity

New in @japplphysiol: Does #COVID-19 impair V̇O2peak in patients with cardiorespiratory disease? Insight from cardiopulmonary responses to maximal #exercise pre- and post-illness (@Igor_Alex_1981 et al.) ow.ly/hSrv50PZqLp @MayoClinic #ExerciseCapacity #oxygen #SARS-CoV-2

#ArticlesInPress: Sympathetic Neural Overdrive and Diminished Exercise Capacity in Reduced Ejection Fraction Heart Failure Related to Anthracycline- Based #Chemotherapy ( Rodrigues et al.) ow.ly/qYy650PQEgn @allan_kluser @dramarinabond #HeartFailure #ExerciseCapacity

🫀New study compares exercise capacity nomograms for Korean patients with cardiovascular disease (CVD) to Western standards. Lower exercise capacity predicts major adverse cardiovascular events (MACE) in Korean patients. #ExerciseCapacity #CardiovascularDisease #RiskPrediction

🥛 How full is your glass? 📢 It's all relative! #PhysicalActivity intensity relative to #exercisecapacity to characterise can/cannot do - does/does not do profiles for targeted interventions #exercise #behaviourchange

#ArticlesInPress: Impact of Right #Ventricular Reserve on Exercise Capacity and Quality of Life in Patients with Left Ventricular Assist Device (Takenaka et al.) ow.ly/WWK250MEwCK @HokkaidoUni #LeftVentricularAssistDevice #RightVentricularReserve #ExerciseCapacity

#LongCovid & reduced exercise capacity? CLOTS are responsible says American Hematological Society--"patients with raised levels of blood clotting markers were also four times more likely to have an impaired exercisecapacity."hematology.org/newsroom/pres…