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Replying to @doctors_squad
Correct answer: ✅ D) Nephron Let’s go step by step and clarify why the nephron is the correct choice and why the others are not. 🧠 Core concept The kidney performs three essential functions to form urine: 1. Filtration 2. Reabsorption 3. Secretion 👉 The single structural and functional unit that carries out all three processes together is the nephron. 🔬 Why Nephron is correct A nephron is a complete working unit of the kidney and consists of: 1️⃣ Renal corpuscle Glomerulus Bowman’s capsule Site of filtration 2️⃣ Renal tubule Proximal tubule: bulk reabsorption (Na⁺, glucose, amino acids, water) Loop of Henle: urine concentration Distal tubule & collecting duct: fine-tuning via reabsorption and secretion ✔️ Therefore, filtration reabsorption secretion all occur within the nephron. ❌ Why the other options are wrong A) Glomerulus ❌ Performs filtration only Does not handle reabsorption or secretion It is just one part of the nephron B) Medulla ❌ A region of the kidney Contains loops of Henle and collecting ducts Not a functional unit by itself C) Cortex ❌ Another anatomical region Contains glomeruli and convoluted tubules Still not a functional unit 📌 High-yield comparison StructureFunction GlomerulusFiltration only CortexKidney region MedullaKidney region NephronFiltration Reabsorption Secretion ✅ 📝 Exam pearl > The nephron is the smallest unit capable of performing all kidney functions. ✅ Final Answer: D) Nephron
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New Benchmarks in Airway Function and Disease Modeling 🫁 👉t1p.de/m553s Dr. Janna Nawroth and her team at the Pioneer Campus at #HelmholtzMunich have uncovered critical differences between human and rodent airways, reshaping respiratory research. 🔬By mapping mucociliary clearance (#MCC) and refining in vitro cultures, they’ve established new benchmarks for more accurate disease models. 💡Their work reveals key species-specific variations and highlights flaws in existing models, offering new pathways to improve treatments for diseases like #asthma, #COPD, and #cysticfibrosis. @PioneerCampus #MucociliaryClearance #RespiratoryHealth #Biomechanics #Cilia #NatureCommunications #StructureFunction
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#RNAbindingproteins (RBPs): it’s Day 2⃣ of the #EMBLRBP meeting! Session 2 on #StructureFunction of RBPs is about to start! Looking forward to all the enlightening talks! @EMBLEvents
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Fantastic Keynote Lecture by Jenny Van Eyk @1jvaneyk at #CardiacMuscleSociety ➡️ #StructureFunction from organ level #Prot to single cell #Proteomics of #cardiomyocytes and #SANcells ⚡️⚡️@SmidtHeart @CedarsSinaiMed #MassSpect
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1) Excited to share our latest research uncovering a novel conformation-specific binding site for propofol in the voltage sensor domain (VSD) of HCN1 ion channels. science.org/doi/10.1126/scia…
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9 Jan 2025
V useful protein #aminoacid sequence & 3D visualisation tool from Drs. Alessandra Picollo & Michael Pusch. #MDsimulations #proteinfolding #Alphafold #structurefunction
ALLIN: a tool for annotation of a protein alignment combined with structural visualization. From Alessandra Picollo and Michael Pusch @CNRsocial_: hubs.la/Q03105Ry0 #MolecularPharmacology #MolecularPhysiology #ProteinDynamics #Biochemistry #Biophysics #Bioinformatics
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A structural analysis reveals species-specific differences in how the antibody #ImmunoglobulinE binds to its receptor Fc-epsilon-RI and could inform research into improved inhibitors of IgE-mediated allergic responses. @UTokyo_News_en #StructureFunction scim.ag/3ZxbUFf
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A new structural analysis reveals species-specific differences in how the antibody #immunoglobulinE binds to its receptor Fc-epsilon-RI and could inform research into improved inhibitors of IgE-mediated allergic responses.@UTokyo_News_en #StructureFunction scim.ag/3ZxbUFf
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A new study casts light on the structure and function of #GPR6—a #GPCR emerging as a key player in #ParkinsonsDisease—and provides clues that could guide future research and the rational design of more selective drugs. @USCBridge #StructureFunction scim.ag/3ZiEhHh
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A new structural analysis reveals species-specific differences in how the antibody #immunoglobulinE binds to its receptor Fc-epsilon-RI and could inform research into improved inhibitors of IgE-mediated allergic responses.@UTokyo_News_en #StructureFunction scim.ag/3ZxbUFf
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A new study casts light on the structure and function of #GPR6—a #GPCR emerging as a key player in #ParkinsonsDisease—and provides clues that could guide future research and the rational design of more selective drugs. @USCBridge #StructureFunction scim.ag/3ZiEhHh
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17 Oct 2024
A new study on QPatch Compact shows that saxiphilins, special proteins found in certain frog species, neutralize saxitoxins – potentially paving the way for safer seafood and smarter toxin detection. Learn more and read the full paper here: sophion.com/publication/stru…
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9 Jul 2024
Day 3 of #GRC #IonChannels is off & running. Prof. Kenton Swartz @NIH kicks things off w/ Prof Dan Minor @ElectrosomeUCSF talking on "#Electrosomes: Some Assembly Required" #ephys #electrophysiology #patchclamp #structurefunction #cryoEM
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Great paper & nice visualization @ntoniosPantazis - congratulations to you & lab. #calcium #CACNA1B #CaV #ionchannels #Gbetagamma #Gprotein #GPCR #structurefunction #actionpotential
How about some molecular structure fireworks for July 4th?? See how an action potential activates the Cav2.2 voltage sensors (and how that is inhibited by Gbetagamma) in our latest preprint: biorxiv.org/content/10.1101/…
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5 Jan 2024
del Rivero Morfin, Fernández-Quintero, @manubenjohny @ColumbiaPHY et al identify asymmetric conformational changes in the selectivity filter as critical for orchestrating Cav1.3 channel inactivation. hubs.la/Q02fhZNV0 #IonChannels #ProteinStructure #MembraneTransport
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15 Dec 2023
Permeant cations modulate pore dynamics and gating of TRPV1 #IonChannels. A new study from Miriam Garcia-Ávila, Javier Tello-Marmolejo, Tamara Rosenbaum @LutiEmir and León D. Islas @LeonDIslas @UNAM_MX: bit.ly/3R99tVs #CellularPhysiology #Biophysics
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4 Dec 2023
A structural atlas of druggable sites on Nav #ionchannels @tandfchannels ➡️ rb.gy/9jmbq3
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