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3 Sep 2025
🔥 Did you know? Oncogenic drivers like c-MYC don’t just control transcription—they rewire mRNA translation with RBP partners like RBM42. Take our quiz in the new blog see how PubMed.ai can supercharge your oncology research. #CancerResearch #Oncology #TranslationalControl
3 Sep 2025
📌 RBM42 Identified as a Mediator of Oncogenic mRNA Translation Specificity 🔗 Find More Research Here: pubmed.ai/?utm_source=X&utm_… Context - RNA-binding proteins (RBPs) are crucial for post-transcriptional gene regulation. - Aberrant RBP activity contributes to cancer-specific translation programs. Highlights from the new study - Functional screening pinpointed RBM42 as a key mediator of oncogenic mRNA translation. - RBM42 enhances specificity in translational control, favoring cancer-related transcripts. - Evidence suggests RBM42 helps establish a tumor-supportive proteome. - Findings provide a mechanistic link between RBPs and selective mRNA translation in cancer. Implications - RBM42 may represent a novel therapeutic target for disrupting oncogenic protein synthesis. - Highlights the broader need to map RBP-driven translation networks in oncology. #CancerResearch #RNA #TranslationControl #Oncology #MolecularMechanisms
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3 Sep 2025
🔬 Can RBM42 Drive Cancer by Controlling mRNA Translation Specificity? 🔗 Find More Research Here: pubmed.ai/?utm_source=X&utm_… A new functional screen highlights RBM42, an RNA-binding protein, as a central player in oncogenic mRNA translation. Key insights to consider: - RBM42 selectively regulates translation of cancer-associated transcripts. - This activity creates a proteomic bias that favors tumor growth. - The study sheds light on how RBPs act as post-transcriptional gatekeepers in malignancy. 💡 Discussion Point Could targeting RBM42 or similar RBPs open a new frontier in anti-cancer therapy? Or will the redundancy of RNA regulatory networks make them challenging drug targets? #Oncogenesis #RNAResearch #RBPs #CancerMechanisms #TranslationalControl
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NetStart 2.0: prediction of eukaryotic translation initiation sites using a protein language model. #TranslationInitiationStart #TranslationalControl #DeepLearning #ProteinLanguageModel #BMCbioinformatics #Genomics #Bioinformatics bmcbioinformatics.biomedcent…
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Predicting the translation efficiency of messenger RNA in mammalian cells. #TranslationEfficiency #TranslationalControl @NatureBiotech nature.com/articles/s41587-0…
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eIF1 and eIF5 dynamically control translation start site fidelity. #TranslationalControl @NatureSMB nature.com/articles/s41594-0…
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UTRGAN: Learning to Generate 5’ UTR Sequences for Optimized Translation Efficiency and Gene Expression. #5UTRs #TranslationalControl #TranslationOptimization #GeneExpression #Genomics #Bioinformatics @BioinfoAdv academic.oup.com/bioinformat…
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A flexible, high-throughput system for studying live mRNA translation with HiBiT technology. #mRNA #TranslationalControl @NAR_open academic.oup.com/nar/article…
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17 Nov 2024
Thrilled to be able to share my PhD work with @FelipeKTeixeira @GeneticsCam doi.org/10.1101/2024.11.14.6… Give us a read if you're interested in #ribosome heterogeneity, #devbio & #translationalcontrol 🪰🔬

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19 Sep 2024
#RNAClub2024 officially began today at @CEITEC_Brno @MasarykUni 🧬 The first block of lectures on Translation is now underway. Let’s explore the latest breakthroughs in RNA research! #GeneExpression #RNAEditing #TranslationalControl #MolecularBiology #RNA
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🔥-off the press: Cap-dependent #translation initiation monitored in living cells: rdcu.be/cYNJ6. Collaborative science during a pandemic❤️ #OpenAccess #TranslationalControl #InitiationFactors #ParticleTracking @GandinValentina @preibischs @MaritzaJaramil5 @HHMIJanelia
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Last week our investigators @aracelly_jga and @thomatican presented their works about #HIV #Zika at #cshl #translationalControl #sciencemadeinchile 🇨🇱
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Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine. #Epitranscriptomics #TranslationalControl #TranslationInitiation #ac4C cell.com/molecular-cell/full… @MolecularCell

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