Joined August 2019
- Tweets 94
- Following 18
- Followers 1,004
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45 Photos and videos
ASHansen Lab retweeted
Come on join us! We are searching for the next technical associate to join our lab ~Summer 2026.
This could be a great position for someone who is graduating this spring and is looking for 2 more years of research experience before starting their PhD:
careers.peopleclick.com/care…
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15 Dec 2025
We had a wonderful time celebrating together at our lab’s holiday party, enjoying good company, good food, and a very fun lab trivia. Grateful for a great year and an even better team!
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ASHansen Lab retweeted
20 Oct 2025
The @Anders_S_Hansen Lab find tiny loops in the genomes of dividing cells. Enabled by a new high-resolution mapping technique, the findings overturn a long-held belief that the genome loses its 3D structure when cells divide. @NatureSMB ow.ly/th0l50Xf782
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ASHansen Lab retweeted
19 Sep 2025
Jamie Drayton and I were fortunate to contribute RCMC to this beautiful paper from Eder, Moene...van Steensel that systematically maps the relationship between enhancer location and gene expression (and nice to see RCMC predict expression in Fig 2H-I): science.org/doi/10.1126/scie…
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ASHansen Lab retweeted
26 Aug 2025
Congratulations to Masahiro Nagano on his new paper on STAG3-cohesin.
STAG3-cohesin has a much shorter residence time which leads to altered 3D genome organization and STAG3-cohesin is important for male germ cell differentiation.
nature.com/articles/s41594-0…
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ASHansen Lab retweeted
12 Sep 2025
Who's up at BATS?
@VarshiniRam23 (@hansen_lab @Anders_S_Hansen): “3D Genomic Mapping Across Human Erythropoiesis” ow.ly/8NXO50WVNaB
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ASHansen Lab retweeted
28 May 2025
Congratulations to Dr. Viraat Goel and Dr. Domenic Narducci, both new PhDs in Biological Engineering from the lab!
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ASHansen Lab retweeted
15 May 2025
(1/13) Thread on @mazzocca_matteo @DomenicNarducci @SGrosseHolz @_jessematthias new preprint
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide some answers
biorxiv.org/content/10.1101/…
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ASHansen Lab retweeted
7 May 2025
(1/n) New preprint from @claricehongky Fan Fang @VarshiniRam23 in collab w Jie Liu
Q: How do we get ultra-high-res 3D genome maps?
A: New deep learning model, Cleopatra.
Cleo trains on Micro-C, fine-tunes on RCMC, and predicts genome-wide 3D maps
biorxiv.org/content/10.1101/…
7 May 2025
Excited to share my first preprint from @hansen_lab! It's got genomics, AI, and biology - all wrapped up in a great paper. Also very grateful to my amazing collaborator, Fan, for all his hard work. Please check it out and let me know what you think!
tinyurl.com/bdfvtd6f
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ASHansen Lab retweeted
14 Mar 2025
Check out Masahiro Nagano's preview sciencedirect.com/science/ar… of a very cool paper from Tjalsma...Wouter de Laat: cell.com/cell-genomics/fullt…
14 Mar 2025
Distance matters: How protein regulators facilitate enhancer-promoter interactions and transcription dlvr.it/TJWy4b
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ASHansen Lab retweeted
16 Jan 2025
Mostly on BlåSky but excited to share James Jusuf's preprint:
By integrating Micro-C with SuperRes Live-Imaging we perform absolute quantification of looping (e.g. this loop is present 3%).
We quantify mESC 36k loops: <loops> are generally rare (2.3%).
biorxiv.org/content/10.1101/…
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ASHansen Lab retweeted
22 Dec 2024
Our preprint by @DomenicNarducci and the companion preprint by @deWitLab are now out in @MolecularCell
ZNF143 is not a general looping factor and was identified as such due to a non-specific antibody. Instead it is TF with the longest residence time measured (to our knowledge)
12 Mar 2024
(1/14) Excited to share our new work on ZNF143/ZFP143 by @DomenicNarducci
ZNF143 has been widely reported to be a general loop factor
Instead we and @deWitLab in a companion preprint show that ZNF143 is a TF with no loop function:
biorxiv.org/content/10.1101/…
biorxiv.org/content/10.1101/…
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ASHansen Lab retweeted
23 Oct 2024
Very grateful to @NIH_CommonFund for funding our Transformative Research Award #NIHHighRisk
8 Oct 2024
#NIHHighRisk Transformative Award recipient Dr. Anders Hansen of @MITdeptofBE will be exploring how transcription factors find their target cites in synthetic and #CancerBiology
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19 Sep 2024
Congrats to @ViraatGoel James Jusuf et al. on new preprint in collab with @Irate_Physicist @blobelgroup @leonidmirny discovering transient microcompartments that connect enhancers and promoters in mitotic chromosomes: biorxiv.org/content/10.1101/…
17 Sep 2024
(1/n) From @ViraatGoel @Irate_Physicist et al. collab w @blobelgroup @leonidmirny biorxiv.org/content/10.1101/…
RCMC at the M-to-G1 transition reveals strong microcompartments between CREs (E,P) in mitosis, that weaken upon G1 entry
Sims reveal chromosome compaction as key regulator
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6 Sep 2024
Come and see James' BATS talk today
6 Sep 2024
First BATS of the academic year 2024/25 🥳!
James Jusuf (@hansen_lab): “Genome-Wide Absolute Quantification of Chromatin Looping”
ow.ly/Coyb50ThrOE
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ASHansen Lab retweeted
28 Aug 2024
Congrats to @GavinSchlissel @Pulin_Li with single-molecule imaging contribution from @DomenicNarducci @hansen_lab
Single-molecule imaging of hedgehog in morphogen gradients reveals a surprisingly complex diffusion mechanism: pnas.org/doi/10.1073/pnas.24…
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ASHansen Lab retweeted
25 Aug 2024
Congrats to @ngaboreden @blobelgroup with RCMC contribution from @ViraatGoel @hansen_lab .
Having recently worked on what we thought was a looping factor (ZNF143 biorxiv.org/content/10.1101/… ) it was amazing to work on a strong Enh-Promoter looping factor LDB1 biorxiv.org/content/10.1101/…
25 Aug 2024
Happy to share my thesis work, now online at bioRxiv. We show that LDB1 organizes Enhancer-Promoter interaction networks and can function independently of cohesin!
biorxiv.org/content/10.1101/…
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