Computational & Genomics Lab studying 3D genome function and dynamics @ Netherlands Cancer Institute
Joined August 2016
- Tweets 904
- Following 254
- Followers 1,768
- Likes 656
84 Photos and videos
You may know ZNF143 as a looping factor. We show together with the @hansen_lab that this is not the case! If you want to know why and what it does instead do read our thread below:
biorxiv.org/content/10.1101/…
7
21
95
17,793
deWitLab retweeted
11 Nov 2024
📢 We are very excited to announce the first International Dutch Embryo Model Meeting in Nijmegen on March 27-28. See below for details.
Don't miss this fantastic opportunity to connect with the embryo model community!
11 Nov 2024
📢 Save the date! I am excited to announce the International Dutch Embryo Model Meeting 2025 in Nijmegen (NL) on Thursday 27 March and Friday 28 March! Registration is open now, or more information: ru.nl/en/about-us/events/int…. Direct link to registration webforms.ru.nl/0d5d3b2f-3d7f….
1
6
731
deWitLab retweeted
8 Nov 2024
Come and join us!
7 Nov 2024
LECTURER position open in the MIT Department of Biological Engineering to join the department as a lecturer focused on teaching the computational aspects of biological engineering. ow.ly/xSbu50U2y8U
1
4
3,190
deWitLab retweeted
5 Nov 2024
Check out our latest review on how cooperativity influences transcriptional bursting. Kudos to the first author Charis Fountas! sciencedirect.com/science/ar…
2
14
50
6,399
deWitLab retweeted
26 Oct 2024
Delighted to see the completed Special Issue of Current Opinion in Genetics and Development on "Genome Architecture and Expression”
It was a pleasure putting this together with Maya Capelson.
Thanks to all the authors that contributed articles
sciencedirect.com/special-is…
2
4
15
1,298
deWitLab retweeted
21 Oct 2024
The protein factories of our cells are much more diverse than we thought. NKI scientists have shown that cancer cells can use ribosomes to boost their invisibility, helping them hide from the immune system. They publish their findings in Cell today ➡️ bit.ly/4ePmIVW
5
18
1,655
deWitLab retweeted
17 Oct 2024
Researchers from the Netherlands Cancer Institute and @prinsesmaximac are launching a new study looking into rhabdoid tumors, a rare and highly aggressive form of childhood cancer, thanks to financial contributions from @kika8118 ➡️ bit.ly/3zPw9Wc
1
4
654
deWitLab retweeted
15 Oct 2024
Happy to share work with Hadi, Yao & @Maxime_Tortora characterizing the impact of dynamic CTCF barriers for cohesin loop extrusion
biorxiv.org/content/10.1101/…
1
24
82
15,546
Want to do a DPhil @BiochemOxford ? Here is a link (bioch.ox.ac.uk/graduate-abou…) to programmes that admit students. Great labs to choose from. Have a look at kloselab.co.uk if you want to know more what we do in my group! Please RT!
1
30
48
11,794
deWitLab retweeted
9 Oct 2024
🚨🚨🚨
Call is now open!!!
Wanna become our new beloved colleague 🫶🏻🫶🏻🫶🏻 and be part of a stimulating (and friendly) scientific community ???
We are perfectly located in beautiful Paris with exciting work environment and state-of-the-art core facilities
APPLY 👇🏻👇🏻👇🏻👇🏻
1
39
61
15,218
deWitLab retweeted
9 Oct 2024
👀 We're looking for a junior group leader! Join our innovative, curiosity-driven institute in a collaborative, international environment. Full freedom to pursue your research, competitive salary & relocation support.
📅 Apply by Dec 1
Info & application: bit.ly/3BLA3j8
14
30
12,419
deWitLab retweeted
5 Oct 2024
First preprint from the lab 🚨
How can enhancers regulate target promoters across vast genomic distances, and what is the role of cohesin loop extrusion in the process?
biorxiv.org/content/10.1101/…
(1)
20
85
291
39,985
deWitLab retweeted
12 Aug 2024
Paper 🚨! Ecstatic, proud, grateful …Years of dedication from the whole lab, with the exceptional @djkloosterman and the one of a kind #JohannaErbani at its helm. What a journey all the way to @CellCellPress! How did it start (& end)? A 🧵1/n
cell.com/cell/fulltext/S0092…
51
91
394
52,173
deWitLab retweeted
25 Jul 2024
(1/16) Check out our @SimonMJGaudin paper tiny.cc/icuazz from the Canzio lab out in @ScienceMagazine today on how tuning local cohesin trajectories enables differential readout of the clustered Protocadherin (Pcdh) locus across different types of neurons.
3
36
100
19,969
deWitLab retweeted
18 Jul 2024
I'm #hiring a PhD student! Join the Lindeboom Lab at the @NKI_nl on an exciting project to explore oncogenic transcription factor binding kinetics and biophysics using state-of-the-art technologies! Apply now or share this exciting opportunity! nki.nl/careers-study/vacanci…
18
46
7,378
deWitLab retweeted
2 Jun 2024
Immunotherapy before surgery for patients with metastatic melanoma appears to be successful as 59% of patients responds so well that adjuvant treatment is no longer needed, show the results of the NADINA trial presentend at #ASCO24 today by @ProfCUBlankNKI bit.ly/3Vo1hnn
15
41
10,423
deWitLab retweeted
12 May 2024
Might attempt to model a flotillin cage using the AlphaFold3 web server was super fun (original paper: biorxiv.org/content/10.1101/…). Read the thread for a crazy plot twist!🧵👇
7
83
600
219,243
deWitLab retweeted
Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get @Nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? @GoogleDeepMind
8 May 2024
Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/go…
25
335
1,621
675,724
deWitLab retweeted
29 Apr 2024
Interested in using degron tagging to study the function of your favourite protein in genetically engineered mouse models? Check out our review covering recent work in this area: doi.org/10.1242/dmm.050613
1
16
53
4,647
Come join us in Oxford as an Associate Professor in Molecular and Cellular Biochemistry.
We are considering a wide range of research areas, but I would note that we have a vibrant chromatin and gene regulation community.
Happy to answer questions if you are interested.
Please RT!
3
133
179
61,456
deWitLab retweeted
23 Apr 2024
Save the date! June 7th @cdf1530 in Paris, the latest developments in the making of human pseudo-embryos in vitro🤘Open access👍 no registration 🙏RT @AMartinezArias @jacob_hanna @NRivron @nmoris @AlainChedotal @TreutleinLab #JFGuerin #ERialSebbag @the_Node
1
29
71
11,118