Was an honor to speak about productivity-maxxxing like a gosu RTS pro. Thank you for having me!

At our latest YC Paper Club, researchers and builders presented on self-play for LLMs, AI for biology, formal verification, and agentic coding in production. Thank you to our presenters: 00:00 — Francois Chaubard (@FrancoisChauba1) | Introduction & Call for Presentations 05:47 — Yasa Baig (@BaigYasa) | A World Model of Protein Biology (biohub.ai/esm/protein/about) 25:38 — Luke Bailey (@LukeBailey181) | Scaling Self-Play with Self-Guidance (arxiv.org/pdf/2604.20209) 37:51 — Arnab Maiti | Stream RAG: Instant and Accurate Spoken Dialogue Systems with Streaming Tool Usage (arxiv.org/pdf/2510.02044) 47:40 — Robert Joseph George (@Robertljg) | Lean and the New Era of Verified Intelligence (arxiv.org/abs/2602.22631) 58:52 — Lukens Orthwein (@lukensort) | Founder AI Hacks: Programming is an RTS Game Now 1:16:07 — Closing Remarks

The Pope rightly warns that AI must serve human dignity, not become a tool of domination or exclusion. But if we hand governments sweeping power over AI development in the name of safety, how do we prevent it from being used to censor, surveil, and control citizens — as Orwell foretold in 1984? This is the real alignment problem. “Quis custodiet ipsos custodes.” Who will guard the guardians? “Power tends to corrupt, and absolute power corrupts absolutely.” The oldest questions of human nature and authority don’t disappear in the AI age. They become newly relevant.

I hope people in tech realize that if you don't support Trump, you get this.

🚨 Do you understand what just happened? New York wants to ban AI from answering questions about medicine, law, and engineering. Let me translate that for you: > The industries charging you $500/hour just lobbied to make sure you can't get the same answers for free. > This was never about safety. It's about protecting the bill rate. > Lawyers don't want you to know AI can draft a contract in 30 seconds. > Doctors don't want you to know AI can read your bloodwork better than a resident. > Engineers don't want you to know AI can review your blueprints overnight. They're not banning AI to protect you. They're banning it to protect their invoices.

This will add an entire other 1% to the global GDP

Merry Christmas. In 1946, C.S. Lewis penned a Christmas sermon in which he wrote: “All over the world… men & women will meet on December 25th to do what is a very old-fashioned &, if you like, a very Pagan thing—to sing & feast because a God has been born. You are uncertain whether it is more than a myth. Well, if it is, then our last hope is gone. But is the opposite explanation not worth trying? Who knows but that here, & here alone, lies your way back not only to Heaven, but to Earth too, & to the great human family whose oldest hopes are confirmed by this story that does not die?” #MerryChristmas2025

I am actually the lead and corresponding author on the most cited research paper of this person's career. Someone told me that today, and I verified it. The claim that her work has had any substantial effect on breast cancer is a dramatic overstatement. Like much of what’s being presented in this 60 Minutes segment, it’s a PR narrative designed to grab money. It’s dishonesty from these institutions about what technology from the life sciences can actually do—and it says more about the way universities grift the public for sympathy and funding than anything about science itself.

With Climate Doomerism fading, AI Doomerism will become as the central organizing catastrophe on the Left. It justifies their takeover of the economy and especially the information space. And it has enough pseudoscience and Hollywood storytelling behind it to seem compelling.

Grokipedia clears Gamergate, tells the truth. It's never been told like this before. It's more than fair. It documents nearly everything. While it does not report the bomb threats and doxing that Gamergate received (with receipts), and does not challenge the claims of Sarkesian and Quinn, I think it's pretty fair. The most fair it has ever been and the REAL story, not the fabricated lies that Wikipedia peddled for years, regurgitating the manufactured slop by game journalists. Thank you, @elonmusk. Link in reply to the article.

New episode: "How Elon Works" This episode covers the insanely valuable company-building principles of Elon Musk A few notes from the episode: 1. The mission comes first. 2. Retreat is not an option. 3. A maniacal sense of urgency is our operating principle. 4. Product design should be driven by engineers. 5. You should not separate engineering from product design. 6. Having separate design and production departments is bullshit. Keep everything together and feedback immediate. 7. The leader should be on the front lines. You should be a battlefield general. 8. "If they see the general out on the battlefield, the troops are going to be motivated. Wherever Napoleon was, that's where his armies would do best." 9. Apply The Algorithm constantly. (1) Question every requirement. (2) Delete any part of the process you can. (3) Simplify and optimize. (4) Accelerate cycle time. (5) Automate. 10. Repetition is persuasive. "I became a broken record on the algorithm. I think it's helpful to say it to an annoying degree." 11. You should go ultra-hardcore on deletion and simplification. 12. Camaraderie is dangerous. It makes it hard for people to challenge each other’s work. (Refer to point #1) 13. Never ask your troops to do something you wouldn’t do. 14. Hire for attitude. Skills can be taught. Attitude changes require a brain transplant. 15. Good attitude = A desire to work maniacally hard. 16. The only rules are the ones dictated by the laws of physics. Everything else is a recommendation. 17. Keep your entire company committed to a common goal. 18. If things aren’t going well, throw away the existing design, start from first principles, question every requirement based on fundamental physics. 19. Find the limit. You want to delete as much as possible and you can’t do that unless you find the limit. 20. If you aren’t adding back at least 10% of the things you deleted, then you didn’t delete enough. 21. Maintain control. Avoid joint ventures. Eliminate middlemen. 22. Have a relentless dedication to questioning every requirement. 23. No work about work, just work. 24. Go to the problem. Get on the plane. Fly to the source. Go to the exact location in the factory. Go to the problem and stay there until it's resolved. 25. The best part is no part. 26. Be wired for war. 27. Do not fear losing. It hurts the first 50 times but then you’ll be able to play with less emotion. You will take more risks. 28. Stay heads down focused on doing useful things for civilization. 29. When something is important and has to be done quickly, have meetings every 24 hours to run the algorithm and check on the previous days progress. You'll be shocked at how fast this speeds things up. 30. Life needs to be interesting and edgy. 31. Delete, delete, delete, delete. There are 100 more ideas in the episode. I hope you listen to it. 30 years of Elon’s career 60 hours of reading and research and me just absolutely ripping through idea after idea at 2x speed for 90 minutes. It will be hard to find a better use of time.

I read your post. It claims that the controversy surrounding Anthropic is about AI safety research. This is not true; in fact, it’s misdirection. The real issue is not research but rather Anthropic’s agenda to backdoor Woke AI and other AI regulations through Blue states like California. This is not surprising since Anthropic hired the Biden AI team, which gave us Biden’s Woke AI executive order and the Biden Diffusion Rule. Since President Trump rescinded these biased and burdensome regulations, Anthropic has shifted its efforts to the state level. It has also fashioned itself into a Resistance organization, opposing President Trump’s One Big Beautiful Bill and export policy. It’s likely not a coincidence that the biggest Democrat mega-donors in tech — namely you, Reed Hastings and Dustin Moskovitz — are closely associated with this company. As I’ve said before, it’s a free country. Anthropic is welcome to oppose the administration as much as it wants. But let’s not pretend this is about AI safety research.

Scott Weiner’s rushing to defend Anthropic tells you everything you need to know about how closely they’re working together to impose the Left’s vision of AI regulation.

Anthropic is running a sophisticated regulatory capture strategy based on fear-mongering. It is principally responsible for the state regulatory frenzy that is damaging the startup ecosystem.

BREAKING - A video of a suspected federal agent breaching the Capitol on J6 and blaming an innocent bystander is going viral after the FBI admitted nearly 300 “plainclothes” agents were embedded in the crowd that day.

This is the truth. Consider how strong, grounded, and resolute we each must be to get 1000x stronger without resorting to the lies, manipulation, and terroristic violence of the left. This is our collective cross to bear.

The President has three and a half years left. Let’s make them count.

God protect you @charliekirk11

Gaming’s gonna reach psychedelic levels of immersion soon