MrBeast reveals why a 10% better video gets you four times the views, not 10% more "I mentor YouTubers a lot. One of the people I've been mentoring recently, he was doing $24,000 a month and then he recently had a $400,000 a month on YouTube." "He was doing 4 million views a month, 24 grand. And then probably like seven, eight months into it we got him up to 45 million views." "It's much easier, as weird as it sounds, it's much easier to get five million views on one video than a hundred thousand views on 50 videos." "You could upload one great video a year and get more views than if you uploaded 100 mediocre videos." "If you get people to click your video 10% more and watch a video 10% longer than mine, you don't get 10% more views. You get like four times the views. A 10% better video is four times the views, not 10% more views."

Exercise rewires the brain to break negative thought loops. The gym bros were right.

I feel like there are two secrets to being really productive with ai 1. Understand your problem well enough to describe and design the kinds of tests that will truly catch failures 2. Get your agent to delegate all its work to other agents in clean context windows

Envy and resent act as a dominant negatives on your ability to be inspired. Protect that ability at all costs.

Anthropic

“Exposure to respiratory viruses before a baby’s first birthday — when immune systems are immature and before most childhood vaccinations — consistently predicted reduced earnings, education and health decades later.”

The probiotics you take during pregnancy may have the ability to confer massive, life-long immunity and protective effects against disease to your child. Continuous daily supplementation of lactobacillus rhamnosus HN001 given to mothers during late pregnancy/breastfeeding halves the risk of eczema. Follow-up studies show this early-life intervention keeps protecting children, significantly reducing the prevalence of eczema and hay fever up to 11 years of age While beneficial, most probiotics taken in adulthood cannot colonize the human gut. Infancy represents a critical, time sensitive window for gut development, sometimes referred to as a "once-in-a-lifetime" opportunity to shape the microbiome. During adulthood, the gut microbiome is highly stable and resilient. Introduced probiotics act like transient visitors. they provide therapeutic benefits as they pass through, but they rarely find an open ecological niche to permanently settle and colonize.

Microneedling Minoxidil grew 4x more hair than Minoxidil alone. Hair count increase after 12 weeks: Minoxidil alone: 22.2 hairs/cm² Microneedling Minoxidil: 91.4 hairs/cm²

I filmed a tour of my home/garage gym. Part product review, part sharing my framework on how I think about the equipment I need to support my goals. Hope you find it interesting. Featuring @Fedfitglobal @GoZwift @wahoofitness @concept2

Said many times, peripheral catecholamines often mirrored by mesolimbic dopamine levels, but not always. While here: the paper you always cite on real time brain DA dynamics (with you as an author)… well the PI who led that study contradicted your interpretation. YOUR coauthor.

are you telling me we made it to 2026 before someone was like "hey what happens if we give the magic mushrooms to people with alzheimer's"

Short-term collagen peptide supplementation increased a marker of bone formation, altered osteoclast-related signaling, and reduced IL-6 in endurance-trained premenopausal women. Study - frontiersin.org/journals/nut…

Paul Saladino is incredibly good at taking everything Dr. Rhonda Patrick taught us and pretending like he said it first.

Creatine dose, benefits & safety from Dr. Rhonda Patrick: - Standard muscle dose is 5 g/day of creatine monohydrate - the most well-researched form - but muscles are "very greedy" and consume most of it before it reaches the brain. - Getting creatine into the brain requires higher doses: one German study found that at 10 g/day, MRI scans showed creatine levels rising in key brain regions above what the brain produces on its own. - Creatine shines under brain stress - sleep deprivation, intense cognitive work, travel fatigue. One study gave sleep-deprived subjects 0.35 g per kg bodyweight (roughly 20-25 g) and they performed not just at baseline but above it. - The phosphocreatine system has a frontal bias - the brain areas most associated with strategic planning and working memory rely on it most heavily. "It's one of the most well-studied supplements out there. If it was unsafe, we really would know." @foundmyfitness on @hubermanlab

one of the quotes i find most inspiring on a hard day: "Whatever your hand finds to do, do it with all your might, for in the realm of the dead, where you are going, there is neither working nor planning nor knowledge nor wisdom" Ecclesiastes 9:10

This has fundamentally changed how I use Codex - everything runs out of a single persistent thread (my "chief of staff") - anytime I start a new project or workstream, I have that thread spin up a new thread (because it's already found the context from slack, etc) - the CoS thread checks in on the project threads during heartbeats, and occasionally sends relevant updates from slack to that thread everything flows naturally to the top

If you ever get tired of managing your Codex threads, just let Codex manage itself! Codex can now create threads, search them, organize them, pin the important ones, and spin up worktrees for parallel tasks.

BREAKING: California will impose a 100% tax on payments distributed from Trump’s Jan. 6th “slush fund.”