MD/PhD @StonyBrookU | PhD in mycobacterial genetics in the @jcslab | incoming FM PGY-1 @ruralresidency
Joined April 2010
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At last, in print sans "pre-"! Grazie mille to my co-authors/co-conspirators @jcslab at beyond, w/o whom I'd still be stuck on a translation problem! TL;DR: Mtb codon context bias may be baked in to regulate transcription, but I hope you'll give it a read. journals.asm.org/doi/10.1128…
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30 Mar 2023
FINALLY! Thanks to the indomitable @JaisinghaniN87 we proudly present the ultimate Mtb cell wall proteome and some surprising-- and exciting-- members: Type VII secretion substrates EsxB & EsxG! 1/n biorxiv.org/cgi/content/shor…
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Infinite thanks to @jcslab and the many brilliant/generous collaborators who made this science adventure possible! ✨💕🥲 And thanks, of course, to mycobacteria for being such interesting weirdos.
20 Mar 2023
Hurrah! Announcing the awesome thesis work of @noosly!
Or, how synonymously recoding genes in mycobacteria is like Bjork’s “It’s Oh So Quiet”. 1/n biorxiv.org/content/10.1101/…
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Nuri retweeted
20 Mar 2023
Hurrah! Announcing the awesome thesis work of @noosly!
Or, how synonymously recoding genes in mycobacteria is like Bjork’s “It’s Oh So Quiet”. 1/n biorxiv.org/content/10.1101/…
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Nuri retweeted
7 Aug 2022
New preprint — and a new (to our knowledge) mechanism by which synonymous codons can regulate gene expression!
Looking forward to feedback.
7 Aug 2022
Synonymous codon substitutions regulate transcription and translation of an upstream gene biorxiv.org/cgi/content/shor… #bioRxiv
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10 May 2022
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9 May 2022
Check out our, @GeneWeiLiLab @julianstanley_, new paper showing that a large fraction of RNA molecules in bacteria are fragments of canonical full-length mRNAs with consequences for differential RNA-seq analysis: doi.org/10.1093/nar/gkac295
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Nuri retweeted
29 Oct 2021
Synonymous sequence changes are not necessarily silent, and here they can have life-or-death consequences.
Now out in @eLife by former lab members @JIPerlmutter and Jane Meyers. Thanks to editors and reviewers for the constructive and kind review.
elifesciences.org/articles/6…
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Nuri retweeted
30 Sep 2021
Happy to have penned this review on bacterial lipidomics with @JaisinghaniN87! All reviews co-edited with @basktastic for this #lipidtime issue coming soon....
Free access to our paper: sciencedirect.com/science/ar…
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Nuri retweeted
12 Aug 2021
🚨I wrote a big piece about how Delta affects the pandemic endgame.
Many folks are upset & confused by the last month. Here's an attempt to reset expectations, lay out our goals, map the near-term future, & show how the pandemic ends--which it will. 1/
theatlantic.com/health/archi…
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Nuri retweeted
13 Jul 2021
JSeeliger Lab is hiring a postdoc! See official ad below and please help spread the word.
Wanted: #microbiology /#biochemistry/chem bio experience and eagerness to explore all things mycobacteria w/ a focus on the cell envelope.
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Nuri retweeted
10 Jun 2021
Excited for @BBM today and tomorrow! For fun in mycobacteria visit @jcslab 5-min poster talks:
#47 @noolsy - unexpected consequences of gene recoding on expression
#58 @LiaParkin - exploring lipid transport functions of a membrane transporter and lipoprotein
10 Jun 2021
Welcome to our annual meeting #BBM2021! You can watch a stream live here: youtube.com/watch?v=faAVHOLB…
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Nuri retweeted
21 May 2021
'I will do it tomorrow,' said Toad. 'Today I will take life easy.'
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17 Apr 2021
Excited to share our first preprint on inhibitors of M. tuberculosis that we characterized using a competitive activity-based protein profiling platform. A long-haul team effort from @jcslab @AldridgeLab @canaanlab and the Cravatt lab. 1/n
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14 Jan 2021
“What is true for E. coli is true for the Elephant” - J. Monod. “But not for Salmonella” - E. Groisman
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