Professor of Neuroanatomy @UniLeipzig. Interested in myelin disorders and regeneration. Find me there: @rfledrich@mstdn.science

Joined June 2018
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Excited to share the latest study on peripheral nerve repair by the Stassart/Fledrich lab! See how Schwann cells communicate with adipocytes to adjust their metabolism for successful regeneration. sciencedirect.com/science/ar…

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Thrilled that the DFG will fund our #NeuroTune graduate school in Leipzig with €5.7M for 5 tandem projects creating over 40 PhD positions. The Stassart/Fledrich lab is proud to host two projects, exploring adaptive myelination in diverse contexts. tiny.cc/3fyvzz
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A beautiful study showing how PMP22 affects the lipid metabolism of Schwann cells in CMT1A.
I'm very proud that my main study from my PhD is finally out in the journal Brain! This was a huge collaborative project that took several years but I'm happy with the result!
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Robert Fledrich retweeted
Happy to share that my PhD project found a home with @EmboMolMed! We pharmacologically and genetically modified aberrant myelin growth in rodent models of PMP22 gene dosage diseases. Details below 🧵
Targeting PI3K/Akt/mTOR signaling in rodent models of #PMP22 gene-dosage diseases. By D. Krauter, M.W. Sereda & colleagues @mpi_nat #PeripheralNeuropathies 🗞️doi.org/10.1038/s44321-023-0…
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Robert Fledrich retweeted
We are looking for a postdoc to investigate behavioural & functional correlates in zebrafish with mutations in autism genes. Great opportunity to develop a new research direction towards studying the role of glia in neurodevelopmental disorders. Please RT elxw.fa.em3.oraclecloud.com/…
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Robert Fledrich retweeted
Happy to be part of this nice review in Cold Spring Harbor Perspectives in Biology with @ruth_stassart and Alison Lloyd cshperspectives.cshlp.org/co… @isabial_iis @NeuroAlc

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With the passing of Laura Feltri we lost a valued colleague who made incredible contributions to PNS research and beyond. She leaves behind a legacy that will be remembered. My deepest condolences to her family and friends.
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Robert Fledrich retweeted
20 Dec 2023
🚨We are hiring at the postdoctoral level. 🚨 RT very much appreciated!🤗
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Robert Fledrich retweeted
Injury to peripheral #nerves in the body can result in pain and movement disorders. Scientists at #UniLeipzig have recently investigated how damaged nerves can regenerate better. Fatty tissue supports the healing process. #Medicine @RFledrich uni-leipzig.de/en/newsdetail…
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Robert Fledrich retweeted
New! Online now: Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration dlvr.it/Sz4qhM
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Excited to share the latest study on peripheral nerve repair by the Stassart/Fledrich lab! See how Schwann cells communicate with adipocytes to adjust their metabolism for successful regeneration. sciencedirect.com/science/ar…

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Acute nerve injury triggers leptin receptor expression by Schwann cells. Leptin released from adipose tissue then stimulates mitochondrial respiration and myelin autophagy in Schwann cells to promote nerve repair.
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Great job @vks24865, Vlad and Nele! Big thanks to @DoctorPAF , @pepegosaelx , @ClaraMutschler, @annaslbch, @emh_es, @TheresaKungl, @KlausNave, @ost_mario and everybody involved!
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Robert Fledrich retweeted
So yes, our paper is out! nature.com/articles/s41593-0… Here's how the story unfolded - thread below🧵👇
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Robert Fledrich retweeted
New study on multiple sclerosis: Myelin may be detrimental to nerve fibres. Joint research by #UniLeipzig and @mpi_nat. @RFledrich uni-leipzig.de/en/newsdetail…
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Robert Fledrich retweeted
Do you agree that animal research is essential in #Biology & #MedicalResearch? 📢The EU will be discussing a complete ban of animal research - Please support this initiative pro animal research in Europe & spread the word 🙏 braincouncil.eu/pledge-for-s…
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Robert Fledrich retweeted
3 Apr 2023
Delighted to see our work highlighted on the cover of JCB. What a great celebration of a brilliant PhD thesis by our talented Nina Kozar-Gillan. @ninakozar et al @JCellBiol (bit.ly/3Kjmslg) @EdinUniNeuro
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Robert Fledrich retweeted
Happy to share great work from @DoctorPAF lab, thanks to the wonderful work of @shaline_v, @ClaraMutschler and our lab @MyelinAlicante. Thanks also to @MonkLab1, Robin, Roger, Benjamin and especially @Lab_Coleman for their support. doi.org/10.3389/fncel.2023.1…

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