Writing about negative data was fun because I read a bunch of Stephen Jay Gould, plus a related commentary by Howard Bowerman. Both provided fantastic examples outside cell biology and biomedicine that perfectly highlight the universality of this issue:

Reductionism has been a powerful force for understanding fundamental aspects of complex systems, but its very success has blinded most biologists to its crippling inability to make sense of complex emergent dynamic systems. We have the tools now to noninvasively observe and perturb living cells in their stunning holistic complexity, but the tyranny of reductionism has reserved the most important tool of all, AI, to approaches (e.g., structural biology, genomics, and spatial transcriptomics) ill-suited to their practitioners stated goal of building "virtual cells". It's been very frustrating convincing the gatekeepers of large HPC clusters otherwise.

Every perspective piece of "virtual cells" consistently ignores cis regulation. You can mark my words. No truly biologically causal "virtual cell" without learning how DNA, RNA & proteins directly mediate gene regulation. 6/

A book and a letter that changed my life. After I read The Geometry of Biological Time, I wrote to its author and asked if I could come work with him. His reply, scrawled in his characteristic magic marker, led to his becoming my most important mentor.

“Publishing our previous papers in LSA has enhanced their reach, fostered interdisciplinary engagement, and increased impact.”— Carsten Gram Hansen @gram_lab. Publish in LSA, where scientific excellence sets the standard: hubs.la/Q04dwhdc0

In our LSA Immunology Collection: TRPM7 and magnesium coordinate the activation and differentiation of human CD4 T-cells. #Immunology #Biology life-science-alliance.org/co…

can’t believe people are complaining my paper is wrong. did you even read the “Limitations” section, where I wrote “This paper is wrong.”?????

As an editor who gladly publishes purely descriptive papers (including atlases) 🙋‍♂️

Spent a delightful week visiting my colleagues @EMBOPress and attending the super stimulating @EMBLEvents symposium on phase separation in cell biology. Everything an editor wants in one place 🥰

As an editor who reads 1000s of manuscripts: yes

“Nature-level” “nature-style” … Nature journal’s branding is so powerful that just making your plots appear like theirs is sold as a benefit. And I don’t think Nature enforces a specific style for plots anyway??

Editors are absolutely not scrutinizing images by eye and just "missed" this. Certainly not at Cell Press! This kind of image duplication is trivial to detect with very standard QC checks. Why would the journal let this issue go uncorrected?

The biggest innovation in vaccines in recent years (mRNA) actually sidesteps the very cells that we are all taught are essential for vaccines to work.

BATF3 is involved in memory T cell differentiation. Here the authors take a deep dive into its potential promoting CAR T cell functions. They profile epigenetic rewiring and provide detailed comparisons with the related BATF. Congrats to the authors on this impressive study!

Abstract submissions for Cell Bio 2026 are now open Share your latest research with the global cell biology community & connect with peers from around the world. Submit by June 9 for full consideration. Late-breaking abstracts are accepted through Aug 4. ascb.org/cellbio2026/abstrac…

Hello Boston! We're looking forward to meeting everyone at IMMUNOLOGY2026 #AAI2026! Stop by 📍Booth 1018 anytime to chat about our journals and pick up a copy of the @JExpMed Immunology collection magazine and a souvenir!