We use yeast to understand the molecular mechanisms of cellular protein homeostasis. Account is run by members of the lab.
Joined January 2021
- Tweets 374
- Following 929
- Followers 1,132
- Likes 202
3 Photos and videos
Pinned Tweet
13 Jul 2021
… aaand the Andréasson lab is finally online!
Make sure to visit our new homepage, where we post about #proteostasis, current projects and #jobopportunities!
andreassonlab.com/
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AndréassonLab retweeted
24 May 2024
From MBoC
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding
Cells counteract stress by inducing adaptive transcriptional programs. Hsf1 in yeast is solely responsible
doi.org/10.1091/mbc.E23-05-0…
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13 Aug 2024
Our new paper: Misfolded proteins activate HSF1 by releasing it from Hsp70. This has been clear in yeast for some time and we find that the mechanism is similar in human cells. sciencedirect.com/science/ar…
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AndréassonLab retweeted
10 Aug 2024
Latest paper from my former lab- congrats, guys @AndreassonLab
Protein misfolding releases human Heat Shock Factor 1 (HSF1) from HSP70 latency control sciencedirect.com/science/ar…
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15 Feb 2024
Very happy to share our latest findings: A novel chaperone – Chp1 – functions at the ribosomal tunnel to safeguard the biosynthesis of abundantly expressed eEF1A. Great collaboration with @BukauLab
@hauryliuk and many others! rdcu.be/dyFTI
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AndréassonLab retweeted
14 Feb 2024
I'm so happy that the first paper from my PhD is finally published🙊. We define the tethers in the yeast vacuole-lipid droplets #membranecontactsite and their role in microlipophagy. Major thanks to all the people that contributed to make this story happen 😁
14 Feb 2024
We are so proud to share the final version of our latest #MembraneContactSites story🎉, now in @Dev_Cell. We identify the LDO proteins and Vac8 as a tethering pair between the vacuole and lipid droplets (vCLIP) that mediates microlipophagy in starvation
cell.com/developmental-cell/…
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15 Feb 2024
Very happy to share our latest findings: A novel chaperone – Chp1 – functions at the ribosomal tunnel to safeguard the biosynthesis of abundantly expressed eEF1A. Great collaboration with @BukauLab @hauryliuk and many others!
rdcu.be/dyFTI
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AndréassonLab retweeted
14 Feb 2024
We are so proud to share the final version of our latest #MembraneContactSites story🎉, now in @Dev_Cell. We identify the LDO proteins and Vac8 as a tethering pair between the vacuole and lipid droplets (vCLIP) that mediates microlipophagy in starvation
cell.com/developmental-cell/…
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AndréassonLab retweeted
12 Jan 2024
We are very proud to share our latest work describing the role of nuclear Hsp104 in protecting the translation machinery during quiescence
nature.com/articles/s41467-0…
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AndréassonLab retweeted
30 May 2023
🎉We are thrilled to share our exciting new collaboration with @inada_lab and @jingdongcheng on how Otu2 recognizes and deubiquitinates 40S ribosomes after translation. Here is a thread with the most interesting findings:👇 #ribosome #ubiquitin #cryoEM
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AndréassonLab retweeted
29 May 2023
We're happy to share a new paper (the 1st one!) from our SUMO project. A short summary follows. jbc.org/article/S0021-9258(2…
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AndréassonLab retweeted
14 May 2023
Publication alert 🚨In our manuscript, we provide robust methods to biochemically and structurally analyze #mitoribosomes: Yeast Mitoribosome Purification and Analyses by Sucrose Density Centrifugation and Immunoprecipitation pubmed.ncbi.nlm.nih.gov/3716… @Ott_MitoLab #Mitochondria
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AndréassonLab retweeted
15 May 2023
The TIM23 translocase of the inner membrane of mitochondria stabilizes PINK1 and thereby directly influences the distribution of Parkin. Beautiful mechanistic @CellReports study by Toshihiko Oka and Toshiya Endo relevant for mitophagy and parkinson. cell.com/cell-reports/fullte…
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8 May 2023
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding | bioRxiv biorxiv.org/content/10.1101/…
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AndréassonLab retweeted
26 Apr 2023
Check out this week's selection of publications on #MembraneContactSites!
biomed.news/bims-mecosi/2023…
My favourite:
doi.org/10.1038/s41556-023-0…
Thanks to @Bims_BiomedNews for the pre-selection!
#ParkinsonsDisease #Neurodegeneration #MCS #Mitochondria #QualityControl #ESCRT
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AndréassonLab retweeted
20 Apr 2023
IT'S FINALLY HERE! A story years in the making about how cells handle misfolded proteins in the nucleus and cytoplasm 1/12
#proteostasis #proteinfolding nature.com/articles/s41556-0…
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23 Apr 2023
Chaperone-directed ribosome repair after oxidative damage: Molecular Cell cell.com/molecular-cell/full…
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AndréassonLab retweeted
22 Apr 2023
Back-to-back JBC papers! Happy to share another JBC paper @jbiolchem on the phase separation of bacterial nucleoid-associated proteins. A great collaboration with my departmental colleague, P. Guptasarma @guptasarma_p & his lab @pglab_iiserm @DBS_IISERM
doi.org/10.1016/j.jbc.2023.1…
21 Apr 2023
Happy to share our 4th paper in the Journal of Biological Chemistry (JBC) @jbiolchem (new role of ATP in yeast prion conversion). Congrats @SayantaIISERM (co-corresponding) @AnushaSarbahi (co-first) @_NehaPunia @AshishJ87810510 @AnamikaAvni @anuja_walimbe
doi.org/10.1016/j.jbc.2023.1…
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AndréassonLab retweeted
19 Apr 2023
The proteomic landscape of genome-wide genetic perturbations cell.com/cell/fulltext/S0092…
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AndréassonLab retweeted
18 Apr 2023
The phosphorylation status of Hsp82 regulates mitochondrial homeostasis during glucose sensing in Saccharomyces cerevisiae
#Proteostasis sciencedirect.com/science/ar…
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AndréassonLab retweeted
11 Apr 2023
Enhanced Degradation of Mutant C9ORF72-Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection pubs.acs.org/doi/10.1021/acs…
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