Important mechanistic study on ICAHT from our French colleagues @GustaveRoussy highlighting that lymphodepletion alone is insufficient to explain prolonged cytopenia after CART …a second inflammation / CAR-mediated hit within the BM is needed 👆 science.org/doi/pdf/10.1126/…

CAR T cells in the bone marrow maintain an activation state that results in inflammation that leads to hypoplasia @ScienceTM @CBigenwald 🇨🇵 science.org/doi/10.1126/scit…

Modifying a patient’s gut microbiome may enhance the efficacy of CAR T-cell therapy, according to research from @GustaveRoussy published in the AACR journal @CD_AACR. Learn more on the #AACRBlog: brnw.ch/21wTRa6 @CBigenwald

Now online in @CD_AACR: Gut Microbiota Modulation through Akkermansia spp. Supplementation Increases CAR-T cell Potency - by Laura Marcos-Kovandzic, @CBigenwald, Laurence Zitvogel, and colleagues doi.org/10.1158/2159-8290.CD… @GustaveRoussy

3km2 repris aux russes. Notre reportage en Ukraine

Thrilled to share our first study on aging from @MiriamMerad lab @IcahnMountSinai @TischCancer @SinaiImmunol in which we demonstrate how aging promotes cancer. We show that: (1/n) science.org/doi/10.1126/scie…

1/23 We are excited to announce that our most recent study “In vivo dendritic cell reprogramming for cancer immunotherapy” was published in @ScienceMagazine. science.org/doi/10.1126/scie… Here is a summary of what we discovered!

🖼️ Yan Pei-Ming donne un visage à l’Institut avec un portrait monumental du professeur Gustave Roussy. Exécuté et offert par Yan Pei-Ming, peintre franco-chinois de renommée internationale, le portrait en 2,80 mètres par 2,40 mètres du Pr Gustave Roussy est accroché dans le hall de l’Institut, accueillant les patients, leurs proches, les visiteurs et le personnel. 🎯 Il symbolise la mission et l’héritage du fondateur de l’Institut, père de l’oncologie moderne, dont les travaux continuent d’influencer la recherche contre le #cancer. Yan Pei-Ming l’a réalisé à l’occasion des 90 ans de la création par le Pr Roussy de l’Institut du Cancer, et des 150 ans de la naissance de ce médecin-chercheur visionnaire. Lire le communiqué de presse 👉 gustaveroussy.fr/fr/yan-pei-…

Congratulations again to all our #EHAGrants winners here at #EHA2024!

📣 Congratulations to this year's #EHAGrants winners! We look forward to seeing them advance the field of #hematology through new collaborations and resources. Do you have a research idea in need of support? The call for #EHA Grants is now open: eha.fyi/Grants2025

Out in @CellCellPress today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. cell.com/cell/fulltext/S0092…

Proud to share the results of our study on the effect of prostaglandin E2 on T cells, which was just published in Nature in which we discovered a new role for PGE2 in inhibiting interleukin-2 (IL-2) sensing and signalling in tumor-reactive T cells nature.com/articles/s41586-0…

IMPROVING ADOPTIVE CELL THERAPY Deadline for abstract submission at : April 2, 2024 Please submit your abstract to the following address: Improvingact2024@gmail.com

⏳REGISTER NOW⌛️while there's still ⏲️ for the FREE International ImmunoSchool introducing everyone that's interested to experts from around the 🌍 who will be discussing challenges & opportunities for cancer immunotherapy. Sign up here >>> eventbrite.com/e/internation… @miriammerad

Fantastic meeting on Cell Therapy in Paris, May 2024! @j_eyquem @BelkaidLab @FGinhoux @lab_rezvani @MarsonLab @Majzner_Lab @HelftJulie @alena_grosvidal @amigorena @RoychoudhuriLab @LucaGattinoni @drclaireroddie @at_Mitralab @LaurieMengerLab @CecileAlanio @MichelSadelain

For all the cell therapy lovers, don't miss this conference in Paris! @GustaveRoussy @ @FITC_cancer

Very excited to share SOPA! This has been a wonderful collaboration with Quentin Blampey, Paul-Henry Cournède and @FGinhoux We present a technology-invariant pipeline for analyses of image-based spatial-omics. Compatible with the latest technologies! biorxiv.org/content/10.1101/…

🎅Le #PèreNoël a eu un #cancer... et en a guéri grâce aux équipes de @gustaveroussy. 👀Découvrez cette « histoire vraie. » 📽️Conçu par @PublicisConseil, réalisé par Vladimir de Fontenay et produit par @Iconoclast_tv, le film est un #ConteDeNoëlModerne ⤵️ vu.fr/ZnJkK