Exploring the energy-driven organization of chromatin
Joined June 2022
- Tweets 19
- Following 17
- Followers 150
- Likes 10
3 Photos and videos
Pinned Tweet
30 Jun 2023
Two independent #cryoEM studies on hexasome remodeling reached similar conclusions. @EustermannLab @EMBL sends congrats to @yifan_ucsf and Narlikar Labs @UCSF! This is how Science should be @ScienceMagazine
science.org/doi/10.1126/scie…
science.org/doi/10.1126/scie…
1
7
31
4,917
Congratulations to Michael Dorrity of @embl, Heidelberg, Germany on being awarded a FEBS Excellence Award, which provides €100,000 in research funding @mwdorr #FEBSExcellenceAwards febs.org/news/febs-excellenc…
2
4
30
1,916
EustermannLab retweeted
20 Oct 2024
New work from the lab!
James Stowell led this project showing the importance of multivalency and phospho-regulation in mRNA decay. This has many parallels with other mechanisms in gene expression... 🧵 1/
#RNA #NMR #bioRxiv @MRC_LMB @ERC_Research
7
41
181
30,331
EustermannLab retweeted
26 Aug 2024
A huge shoutout to our #EMBOCryoEM participants! 👏 The last 9 days were full of lectures, practicals, and social activities - well done for showing up each day with renewed enthusiasm and making this course memorable ✨
See you again soon? 👉 embl.org/events
3
13
2,021
EustermannLab retweeted
16 Aug 2024
Our latest paper is out today @MolecularCell! Led by a @AHA_Alberto and with important contributions from @SaricLab & @EllenbergLab! We show how chromosomes shift from being repulsive to becoming attractive during mitosis. Read all about it here:
cell.com/molecular-cell/full…
1
19
94
7,873
EustermannLab retweeted
7 Aug 2024
1/ 🤔 Do #chromatinlooping-mediated promoter-#enhancer interactions drive gene expression? Or is the local enrichment of transcription factors into hubs/#condensates the key factor? Our AC/DC model of gene regulation at bioRxiv doi.org/10.1101/2024.08.03.6… provides a new view on this.
4
72
269
29,349
EustermannLab retweeted
2 Aug 2024
Happy to share with the world that the main body of my PhD thesis (and my rotation project) on the mechanism for replisome-mediated parental histone inheritance is published in @CellCellPress today🥰!
cell.com/cell/fulltext/S0092…
6
29
154
18,638
EustermannLab retweeted
18 Apr 2024
BIG NEWS No 2 🥳🥳🥳 ! Together with @PLID_Info @DiabResearch @HelmholtzMunich @tudresden_de and @Medizin_TUD As of April 1st @ingmarschafer of @LabConti and @MPI_Biochem is appointed as Professor and Chair of Structural Membrane Biology at PLID and ZML.
2
5
29
5,892
EustermannLab retweeted
19 Apr 2024
This is an amazing course with an all-star lineup of instructors 🤩
It will cover the theoretical and practical foundations of advanced cryoEM techniques, from sample preparation to data collection to image processing.
You have one month to apply!
18 Apr 2024
Want to learn how to integrate single particle analysis and tomography approaches to your research? Then join #EMBOCryoEM! 🔬
This course will provide the theoretical and practical foundations of advanced cryoEM techniques, so be sure to apply by 26 May👉 s.embl.org/cry24-01
9
34
6,256
EustermannLab retweeted
7 Dec 2023
The simple autophagy adaptor protein Atg18 has many levels of structural self-organization in particular with lipid membranes! Wonderful collaboration with the Andreas Mayer lab (Lausanne) and with two leading authors @FrommSimon @proteincommandr .
doi.org/10.1038/s41467-023-4…
14
59
6,475
EustermannLab retweeted
4 Dec 2023
Congrats @BrahmaComplex!!!
The BAF chromatin remodeler synergizes with RNA polymerase II and transcription factors to evict nucleosomes
nature.com/articles/s41588-0…
3
15
97
12,791
EustermannLab retweeted
26 Oct 2023
1/10 With great pride I present our newest #CryoEM work pub. in @Nature. The 1st reported secondary-active transporter directly activated by membrane voltage. Full credit to the amazing @VKalienkova, @MartinPeter91 & @rheinbergerj 🧵👇🏽 for more info nature.com/articles/s41586-0…
8
38
242
19,222
EustermannLab retweeted
24 Oct 2023
Super excited to present #Blush and with it expand the applicability of cryo-EM. We reconstruct one of the smallest complexes ever with cryo-EM. A 40 kDa protein-RNA complex.
biorxiv.org/content/10.1101/…
But how do we make sure we’re not overfitting?
🧵1/4
6
82
348
33,035
EMBL researchers have provided the first detailed structure of human RNA polymerase III transcription factor IIIC (TFIIIC).
The findings offer vital insights on TFIIIC’s cellular functions to those studying its role in chromatin organisation and cancer.
science.org/doi/10.1126/scia…
5
38
8,743
30 Jun 2023
Special thanks goes to Min Zhang @ChowderMin, Anna Jungblut @EustermannLab and Franzi Kunert @ @hopfnerlab
science.org/doi/10.1126/scie…
12
458
30 Jun 2023
How to remodel a hexasome? Check out our new findings on non-canonical nucleosome remodeling @ScienceMagazine. Great @EustermannLab team effort @EMBL together with @hopfnerlab and Frank DiMaio.
science.org/doi/10.1126/scie…
2
9
64
5,253
New EMBL research by the Eustermann lab reveals how the packaging of DNA into hexasomes impacts the function of remodeling enzymes involved in gene regulation.
Read more: science.org/doi/10.1126/scie…
ALT image credit: Luis Hauptmann / EMBL
6
38
18,616
EustermannLab retweeted
30 Jun 2023
Check out how the INO80 complex interacts with non-canonical nucleosomes. Great team effort by M. Zhang, A. Jungblut and F. Kunert. Congratulations to the @EustermannLab @embl and all authors!!! science.org/doi/10.1126/scie…
New EMBL research by the Eustermann lab reveals how the packaging of DNA into hexasomes impacts the function of remodeling enzymes involved in gene regulation.
Read more: science.org/doi/10.1126/scie…
ALT image credit: Luis Hauptmann / EMBL
19
81
12,345
3 Jun 2022
How are genomes neatly packaged for cell divisions?
Our awesome collaboration with @HaeringLab @EMBL @Uni_WUE reveals intriguing #cryoEM insights into the mechanism of DNA loop extrusion by SMC complexes:
embl.org/news/science/shapin…
ALT Credit: Tobias Wüstefeld/Illustratoren.de. Artists view of condensin folding DNA into loops to build a mitotic chromosome.