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Joined February 2019
- Tweets 376
- Following 341
- Followers 622
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15 Photos and videos
A new study by @LeroyElodie3, Thomas Perry and @ThibaudRenault shows how the antibiotic Tetracenomycin X (TcmX) blocks translation of QK motifs by sequestering peptidyl-tRNA. @ERC_Research @iecb_bordeaux @arna_lab biorxiv.org/content/10.1101/…
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Innis Lab retweeted
11 Jul 2024
Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells!
biorxiv.org/cgi/content/shor…
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Innis Lab retweeted
12 Jun 2024
Ribosome meeting 2024 (Dec 2 - 4) at The institute of Medical Science, The University of Tokyo, organized by Prof Inada. @inada_lab .
inada-lab.ims.u-tokyo.ac.jp/…
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Innis Lab retweeted
4 Jun 2024
Toutes nos félicitations ! 👏👏👏
4 Jun 2024
🔴 EN DIRECT | Cérémonie de réception des nouveaux membres
🌿« STRUCTURE DES RIBOSOMES »
Marat YUSUPOV, Directeur de recherche au @CNRS, Institut de génétique et de biologie moléculaire et cellulaire, section de #BiologieMoléculaireCellulaireGénomique
👉 youtube.com/live/ChRvAxZ8WVY
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Exciting to see peptides targeting new sites on the ribosome and exerting context-dependent effects through novel means! Congrats to all involved at @WilsonLab2 @shuramankin and @Suessmuth_Lab !!!
22 May 2024
Our preprint reporting the structure and mechanism of the natural product translation inhibitors paenilamicins is out…completely novel binding site on the ribosome! dlvr.it/T7CNnf…great collaboration with @Suessmuth_Lab @shuramankin
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Innis Lab retweeted
8 May 2024
Angiogenin controls angiogenesis (et plus) by nicking tRNAs. But it’s barely active alone. We discovered how 80S ribosome unlocks Ang’s active site and “brings in” tRNAs.
Congrats to Anna Loveland and collab. w/@ajplanetearth!
nature.com/articles/s41586-0…
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Innis Lab retweeted
10 May 2024
Read our latest #research on antimicrobial peptides that inhibit the activity of the bacterial ribosome in multiple ways, published in @NatureComms Thx to all co-authors & the members of the Grubmüller, Hoffmann and Spahn groups. rdcu.be/dHxGL
nature.com/articles/s41467-0…
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Innis Lab retweeted
8 May 2024
Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/go…
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Researchers have used generative artificial intelligence to help them make completely new antibodies for the first time go.nature.com/3Vio70e
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Innis Lab retweeted
19 Mar 2024
Our structure of SecM-stalled ribosomes out in @natcomms. rdcu.be/dBJTZ. Great work by @felixgersteuer @MartinoMorici and collaborators, with data collected at the @CssbHamburg by @haaris_safdari
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Not one, but two papers on arrest peptides!! What a day! 😍 Congratulations Daniel @WilsonLab2, collaborators and team! 👏👏👏
19 Mar 2024
We are rapping today about arrest peptides!! Back-to-back manuscripts in @NatureComms showing how RAPP and SecM arrest peptides can stall the ribosome! SecM link here: rdcu.be/dBJTZ nature.com/articles/s41467-0…
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Innis Lab retweeted
10 Mar 2024
The final version of the most recent paper on the ribosome regulatory TnaC peptide and L-Trp saga is finally out. @gentle_heather @shuramankin
Functional domains of a ribosome arresting peptide are affected by surrounding nonconserved residues - jbc.org/article/S0021-9258%2…
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I wrote a review (with @_JosephWatson @sid_thesci_kid ) on protein design using structure prediction models--i.e. hallucination, inpainting, diffusion. This approach to protein design started as a convenience but has turned out to be surprisingly powerful. cshperspectives.cshlp.org/co…
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Innis Lab retweeted
7 Mar 2024
Our work on modeling and designing biomolecular assemblies is now in @ScienceMagazine.
science.org/doi/10.1126/scie…
RFAA Code: github.com/baker-laboratory/…
RFdiffusionAA Code: github.com/baker-laboratory/…
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Innis Lab retweeted
29 Feb 2024
We are #hiring! In collaboration with #Xavier_Guillory, we seek a talented and motivated postdoctoral researcher in #cryoEM to study membrane #kinase receptors involved in human health and diseases.
Please share widely.
nature.com/naturecareers/job…
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Innis Lab retweeted
26 Feb 2024
We reveal the mechanism of bacterial ribosome recycling by HflXr (and HflX). HflXr employs a novel strategy to split the ribosome into subunits
that differs from that mediated by EF-G and RRF
academic.oup.com/nar/advance…
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Innis Lab retweeted
22 Feb 2024
We are thrilled to share our last #research story @NatureSMB describing how the CNK-HYP scaffolding complex activates RAF kinase by enhancing the KSR:MEK interaction. Great collaborations with the Sicheri lab @SinaiHealth and Therrien lab @IRIC_umontreal
rdcu.be/dzjYS
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Innis Lab retweeted
20 Feb 2024
Cresomycin—a novel synthetic molecule—demonstrates remarkably robust efficacy against multiple, evolutionary divergent forms of antimicrobial resistance, researchers report in Science.
Read more: scim.ag/5VZ
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Congratulations Alba! First an HFSP fellowship and now an MSCA fellowship to work on cool new antiviral defense systems @MDMlab_Paris ! 🥳🍾🥂Exciting times lie ahead!!
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14 Feb 2024
We are thrilled to share our new story out @Nature - the discovery of a novel family of ribosome hibernation factors. This is the result of an exciting and stimulating collaboration between three labs @GagnonLab, @SergeyVMelniko1, and @chillzaa
nature.com/articles/s41586-0…
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Innis Lab retweeted
14 Feb 2024
Bacteria have an astonishing ability to put their life on pause in the face of stress and starvation by entering a state of dormancy. Here, we discover one aspect of this remarkable self-preservation strategy: nature.com/articles/s41586-0…
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