Joined December 2017
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Replying to @ScienceRicker
Thanks to the amazing Iana Meitlis who is in UW Med school, Eric Allenspach, Andrew Snow and Dave Rawlings. These methods were based on work by @jshendure, @lea_starita, @TheNobleDust
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Richard G. James retweeted
New research published in @NatureComms from our co-founders Drs. @ScienceRicker and David Rawlings from @seattlechildren shows robust protein production and long-term engraftment of engineered plasma B cells. nature.com/articles/s41467-0… #BeBio #SCRI #Research #BCells
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Richard G. James retweeted
18 Oct 2022
Very happy to see the full story out finally. We had been sitting on some of these exciting findings since 2017! (6/6)
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Richard G. James retweeted
A really cool application of Partillion Biosciences and @10xGenomics technologies to measure secreted proteins together with single cell gene expression.
SEC-seq: Association of molecular signatures with antibody secretion in thousands of single human plasma cells biorxiv.org/cgi/content/shor… #bioRxiv
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Richard G. James retweeted
Congratulations to @bebiopharma on the Series B! This Longwood-founded company is making progress in developing a new class of cellular medicines to help patients.
Today we announced the closing of a $130 million financing round led by ARCH Venture Partners. The funds will support our mission to unleash the power of B cells to drive a new class of cellular medicines. Read more in our press release: bit.ly/37LI3Sn
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Richard G. James retweeted
Bianca Viray, a professor @UW, has been awarded the AMS Joan and Joseph Birman Fellowship for Women Scholars for the 2022–2023 academic year. An arithmetic geometer, Viray researches rational points on varieties. ➡ bit.ly/3sOzka9
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Richard G. James retweeted
Join our team! DIRECTOR OF MUTATIONAL SCANNING This person will lead a team to help bring mutational scanning methods to production scale. Terrific job opportunity with @JShendure @lea_starita Details and how to apply here: bit.ly/3tpPdVo
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Richard G. James retweeted
14 Dec 2021
Until the pre-print posts, I figured I would put together a thread for those who want to see the data. Many thanks to @wilfredo_nk, @kstdenis29, @EvanCLam, @adamnitido, @NaranbhaiVivek who have been up at all hours of the night both at the bench and writing the paper! 1/16
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Richard G. James retweeted
24 Nov 2021
Our paper is out in @Nature! Extrachromosomal DNA molecules huddle together in cancer cells to activate oncogene expression (which we call ecDNA hubs). A great collaboration with @KatieEYost, @HowardYChang, @549nm, Zhe Liu, and others. (1/10) nature.com/articles/s41586-0…
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Richard G. James retweeted
B cells are nature’s medicine factories built to unleash a variety of therapeutic applications. Hear our scientific co-founders, Richard James (@ScienceRicker) & David Rawlings describe the incredible versatility of B cells. vimeo.com/646051754
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Richard G. James retweeted
Introducing NextTrevor, an open-source project to harness publicly available images of @trvrb. We provide a continually-updated view of @trvrb's evolution alongside powerful analytic tools. Our goal is to aid understanding and improve response to changes in his appearance.
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Richard G. James retweeted
Congrats to the hubs, @ScienceRicker, for cofounding @bebiopharma, over zoom, while simultaneously home schooling 6th grade! Exciting technology for the sustained delivery of protein therapeutics. Read more here ⬇️
Our annual survey of some of the best #NBTAcademicStartups in 2020 continues with @bebiopharma, which turns plasma cells into protein factories for patients with protein deficiencies for whom one-and-done gene therapy is not an option nature.com/articles/d41587-0…
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Richard G. James retweeted
Check out our paper —>
Our paper on sci-Space, a spatially resolved version of sci-RNA-seq, is out today! Led by @srsrivatsan and @mregier13, Joint work with @JShendure and @kellystevenslab. (Art by @nigelsussman)
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Your work started @kinglhung - we are super excited to keep it moving forward!
28 Jun 2021
So glad to see that this is gaining traction!
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Richard G. James retweeted
Thanks for featuring @bebiopharma Longwood-founded #celltherapy #newco nature.com/articles/d41587-0…

Our annual survey of some of the best #NBTAcademicStartups in 2020 continues with @bebiopharma, which turns plasma cells into protein factories for patients with protein deficiencies for whom one-and-done gene therapy is not an option nature.com/articles/d41587-0…
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Excited to share our functional data that has helped classify VUS associated with immune dysregulation at #CIS2021 - what a great meeting! Check it out
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Richard G. James retweeted
Thrilled to announce the appointment of Joanne Smith-Farrell and Rick Morgan to the leadership team at Be Bio! businesswire.com/news/home/2…
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Richard G. James retweeted
18 Mar 2021
In new work led by @AllieGreaney, we analyze mutational escape of #SARSCoV2 from monoclonal & polyclonal antibodies in terms of RBD epitope classes (biorxiv.org/content/10.1101/…). Provides useful framework for conceptualizing effects of individual and combined mutations. (1/n)

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Richard G. James retweeted
18 Mar 2021
Finally, enjoyable part of project was getting to build on nice prior work by @cobarnes27 @bjorkmanlab @NussenzweigL @PaulBieniasz @theodora_nyc. We’ve read & enjoyed their papers on #SARSCoV2 antibodies, so appreciated opportunity to get to extend some parts of it. (11/n)
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