We are interested in the immune infiltrate in Breast cancer and what it means for treatment and prevention.
Joined December 2017
- Tweets 253
- Following 109
- Followers 830
- Likes 152
40 Photos and videos
Pinned Tweet
26 Apr 2021
We've recently launched a global survey on the potential use of #TILs for future trial designs and use in daily practice. We would love to hear what you have to say 👇fd7.formdesk.com/BQA/TILs_TN…
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TILs Working Group retweeted
13 Dec 2025
Such a privilege to be part of the international TIL Working Group @TILsWorkGroup and to collaborate with Dr. Salgado on NeoTIL. #SABCS @muschollings @stolaney1 @OncBrothers @LoiSher
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TILs Working Group retweeted
10 Dec 2025
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TILs Working Group retweeted
10 Dec 2025
Amazing presentation by Roberto Salgado from @TILsWorkGroup
TIL assessment of APHINITY using CASE45 AI model and manual TILs (great ICC)
Combining AI and manual assessment is a better prognostic biomarker than either one of them
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TILs Working Group retweeted
11 Dec 2025
TILs matter in HER2 BC!
In ShortHER trial, mapping their spatial organization with AI assessing:
🔹Immune-tumor interaction
🔹Aggregates/TLS (Hotspots)
further refines prognosis beyond manual evaluation
PS2-08-11 at #Sabcs25 @UniPadova @iov_irccs @TILsWorkGroup
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TILs Working Group retweeted
24 Oct 2025
Tagging @TILsWorkGroup to amplify this great work
20 Oct 2025
✨✨hot off the press from the #loilab. We show here that pregnancy & breastfeeding is associated with increased T cells in the normal breast and protection against #tnbc #breastcancer moving the role of immunity from treatment to prevention.
👏👏Thanks to @FAndreMD @DrChoueiri @MyriamChalabi for the opportunity to present #ESMO25 @OncoAlert @myESMO
@PeterMacRes @PeterMacCC @UniMelb
thanks to our funders @BCRFcure @TheMarkFdn @NBCFAus
@Nature Article is here: nature.com/articles/s41586-0…
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TILs Working Group retweeted
20 Oct 2025
✨✨hot off the press from the #loilab. We show here that pregnancy & breastfeeding is associated with increased T cells in the normal breast and protection against #tnbc #breastcancer moving the role of immunity from treatment to prevention.
👏👏Thanks to @FAndreMD @DrChoueiri @MyriamChalabi for the opportunity to present #ESMO25 @OncoAlert @myESMO
@PeterMacRes @PeterMacCC @UniMelb
thanks to our funders @BCRFcure @TheMarkFdn @NBCFAus
@Nature Article is here: nature.com/articles/s41586-0…
20 Oct 2025
Translational data shows that #breastfeeding helps personal immunity improving CD8 T
This work can help to understand better the immune system and breastfeeding mechanisms @LoiSher @OncoAlert #ESMO25 @FernandoOnco
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22 Oct 2025
The EU-funded MSCA Doctoral Network “Spatial Crosstalk in Immune-Oncology” (SpaXio) is now officially recruiting 14 PhD students to decipher the metastasis-promoting microenvironment of colon and breast cancer. More info here: tilsinbreastcancer.org/wp-co…
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TILs Working Group retweeted
11 Oct 2025
😎if #TIL had been the prespecified biomarker, pembrolizumab might well be approved for this indication. PD-L1 IHC has real technical limitations- patients deserve multiple validated ways to identified immune enriched tumors. #TILs are simple, free & readily available- wait 🤔is that the problem? @oncoalert @TILsWorkGroup #bcsm
7 Oct 2025
💫🌟Association of potential biomarkers with clinical outcomes in metastatic TNBC treated with pembrolizumab or chemotherapy
👉 nature.com/articles/s41523-0…
@JavierCortesMD @ProfAnthoG @ASCOPres @Prof_Nadia_H @LoiSher
🧬 KEYNOTE-119 exploratory biomarker analysis
🔹 TILs ≥5% → ↑ ORR, PFS, OS with pembrolizumab (not chemo)
🔹 T-cell–inflamed GEP → predictive of better ORR, PFS, OS
🔹 TMB ≥10 mut/Mb → trend toward longer OS
🔹 BRCA/HRD → no predictive association
🔹 TILs GEP show independent predictive value → immune-inflamed tumors benefit most
🧠 Clinical insight: Immune-active biomarkers (TILs, TcellinfGEP, TMB) identify TNBC subsets deriving durable benefit from pembrolizumab.
@myESMO @OncoAlert @ASCO @NatureCancer @BreastCancerRes
#TNBC #BreastCancer #Immunotherapy #KEYNOTE119 #PDL1 #Biomarkers #OncoTwitter
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4 Jul 2025
Study across 45 institutions shows AI validity in TIL quantification for melanoma. Reproducible with prognostic validity and open-source. @tznaung 👉 jamanetwork.com/journals/jam…
#AIinPathology #Melanoma #ComputationalPathology
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TILs Working Group retweeted
18 Apr 2025
Some studies shows how we can reduce costs based on biomarkers
SHORT-HER 9 weeks of trastuzumab is ✅ based TILS 20% or more
@TILsWorkGroup @OncoAlert #oncoalertAF @JAMAOnc⤵️
jamanetwork.com/journals/jam…
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16 Apr 2025
🎉 Thrilled to share that 2 @JPathol papers from the TILs Working Group ranked in the Top 10% most-viewed in 2023!
👏 Huge thanks to all collaborators, @JPathol & our readers for your support.
📎 Links in comments ⬇️
#TopViewedArticle #TILsinBreastCancer #pathology
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16 Apr 2025
📄 Pitfalls in ML-based TIL assessment
🔗 doi.org/10.1002/path.6155
📄 Spatial analyses of immune infiltration in cancer
🔗 doi.org/10.1002/path.6165
#ImmunoOncology #DigitalPathology #TILs
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TILs Working Group retweeted
11 Dec 2024
Great slide highlighting not only are TILs predictive of pCR...it also translates to being prognostic beyond pCR for good outcome and DFS.
Seems like we have a LOT of data on TILs now, why aren't they standardly provided on path reports???🧐
#SABCS24
@SABCSSanAntonio
@OncoAlert
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13 Dec 2024
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30 Oct 2024
🤩🍾10th anniversary TILs-Working Group at @SABCSSanAntonio 2024 - everyone welcome! RSVP here: forms.office.com/Pages/Respo…
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18 Sep 2024
The largest TILs-Workshop done so far! More than 100 pathologist, residents in training and medical students learning how to score TILs. Organized by the Narayana Medical College, India. Who follows? 💪🏼
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28 Aug 2024
Join us for the 2024 Peter Mac Breast Cancer Medical Oncology Education Day! 📅 On Friday, 11th October, dive into the latest in breast cancer care with experts at Peter Mac or via Zoom. Registrations: shorturl.at/fpr82 @PeterMacRes @PeterMacCC
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8 Jul 2024
5 Jul 2024
Towards targeting the breast cancer immune microenvironment dlvr.it/T9C7GF
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TILs Working Group retweeted
6 Jul 2024
Our latest review is out now on targeting #BreastCancer #Immunity #tme #trm #CancerResearch many thanks to @NatureRevCancer
@PeterMacCC @PeterMacRes @TILsWorkGroup
5 Jul 2024
Towards targeting the breast cancer immune microenvironment dlvr.it/T9C7GF
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