Editor-in-Chief, Blood Cancer Journal; Chairman @IMFmyeloma Board; Cancer & Myeloma Research; Opinions solely personal views bit.ly/3f4TnJl
Joined March 2009
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10 Feb 2021
I would like to share the story of how a patient with cancer came up with the idea for a randomized trial, & how listening to him saved a lot of lives.
1/ In 2002, I had just completed a randomized trial with the notorious drug thalidomide for the cancer, multiple myeloma.
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Vincent Rajkumar retweeted
Reading this as both a doctor and caregiver. Competence and kindness never go out of date. The rest is noise unless it serves them. Thank you for saying it so clearly…
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Symphony No. 1 “New Beginnings” (PROMO) - Award Winning Composer, Orchestrator and Musical Director “Michael Hyman” talks about “New Beginnings” - Full Interview Out Soon!
Audio Launch (not performance) on June 21st (World Music Day) at Music Academy from 4pm onwards - Get your tickets now on @bookmyshow
More updates coming soon!
#Symphony #NewBeginnings #LondonSymphonyOrchestra #MattDunkley
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Vincent Rajkumar retweeted
#EHA2026 plenary session 👏
MonumenTAL-3: Tal-Dara and Tal-DaraPom both beat Dara-Pd in terms of PFS and OS.
This is despite D-Pd doing the best it ever has (mPFS > 2 yrs).
BsAbs, both BCMA and GPRC5D, are here to stay in earlier lines for myeloma!
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Vincent Rajkumar retweeted
MonumenTAL-3 is out in NEJM 🍾
nejm.org/doi/full/10.1056/NE…
Tal-dara-pom and Tal-dara offer superior PFS and OS over DPd. Tal-based combos are a new SOC in 2line RRMM
Congrats to the study team and the co-authors!
@PlasmaCellPete @mbeksac56 @gdnsvl @paurotero @mvmateos
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I’ll update my relapsed myeloma algorithm on @OpenMedInsights @OpenMedicineHQ soon. myopenmedicine.com/algorithm… @scserendipity1
Just out: presented at #EHA26 and published @NEJM
Randomized trial of 2 talquetamab combinations vs DPd in relapsed myeloma. The Monumental-3 trial.
Both Talq-Dara-Pom and Talq-Dara beat DPd in PFS and OS.
Choice of a Talq combination vs Tec or Tec-Dara in relapsed myeloma will be driven by patient and disease factors and requires significant expertise. Congrats @RobertoMinaMD @PlasmaCellPete @mbeksac56 @paurotero @mvmateos @thanosdimop @RahulBanerjeeMD et al.
nejm.org/doi/full/10.1056/NE…
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Just out: presented at #EHA26 and published @NEJM
Randomized trial of 2 talquetamab combinations vs DPd in relapsed myeloma. The Monumental-3 trial.
Both Talq-Dara-Pom and Talq-Dara beat DPd in PFS and OS.
Choice of a Talq combination vs Tec or Tec-Dara in relapsed myeloma will be driven by patient and disease factors and requires significant expertise. Congrats @RobertoMinaMD @PlasmaCellPete @mbeksac56 @paurotero @mvmateos @thanosdimop @RahulBanerjeeMD et al.
nejm.org/doi/full/10.1056/NE…
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And these bispecific regimens need toe weighed against results with CAR-T. nejm.org/doi/full/10.1056/NE…
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Although all 4 trials were done in relapsed myeloma with 1-3 prior regimens, the type of patients varied including by type of prior exposure. So comparing head to head HRs is not advisable.
Patient and disease factors, access, affordability, and shared decision making come into play, especially in first relapse. In second relapse we have to also add belantamab. x.com/openmedicinehq/status/…
May 19
Treatment of Myeloma: First Relapse algorithm from @VincentRK: myopenmedicine.com/algorithm…
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5 years from now or 50 years from now patients still want the same:
Competent and empathetic physicians who are accessible when the need arises, and affordable care.
We cannot wrap stuff with the word “innovation” when the changes in healthcare policies and priorities are reducing the development of clinical excellence, placing barriers to access, increasing cost of care, and accelerating burnout of experienced clinicians.
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Vincent Rajkumar retweeted
Jun 12
Myeloma is Now Becoming a Curable Disease Because the Myeloma Family Works Together - Joshua Richter
@JoshuaRichterMD @VincentRK
oncodaily.com/voices/joshua-…
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Jun 11
Just wrapped up an amazing IMWG summit in Stockholm.
17th year in a row. We saw 17 new myeloma drugs approved in these 17 years.
“The Plasma Cells” honored our Kyle and Durie award winners @H_Einsele @NoopurRajeMD this year as usual with some fun songs. And @JoshuaRichterMD closed it out with a killer guitar solo.
From left: @szusmani @paurotero Francesca Gay, Philippe Moreau, Sonja Zweegman, Niels van de Donk, @mvmateos Enrique Ocio, @SurbhiSidanaMD @VincentRK @JoshuaRichterMD
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Jun 10
RT @singersrinivas: Sad to hear of the passing of Bharathiraja sir.As a teenager, films like 16 Vayathinile, Nizhalgal sh…
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💔
Sad to hear of the passing of Bharathiraja sir.As a teenager, films like 16 Vayathinile, Nizhalgal shaped everything I understood about emotion and storytelling. Getting to sing for his film Taj Mahal years later was one of those moments I still can’t believe was real.Go well sir. Your frames will live forever. 🙏
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Vincent Rajkumar retweeted
Myeloma is now becoming a curable disease because the myeloma family works so well together. Celebrating the spirit of collaboration with the Plasma Cells at #IMWG26. Thanks to @VincentRK and the entire @IMFmyeloma leadership for bringing us all to the table. #mmsm
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Vincent Rajkumar retweeted
Congratulations to Dr. Hermann Einsele and Dr. Noopur Raje, who will be honored today for their extraordinary contributions to myeloma at the 2026 IMWG Summit in Stockholm, Sweden. Learn more: myeloma.org/node/12929
#IMFIMWG
@H_Einsele
@NoopurRajeMD
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Jun 9
Newly Diagnosed Myeloma from @VincentRK: myopenmedicine.com/algorithm…
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Jun 9
Packed room. Endless enthusiasm. The IMWG Meeting in Stockholm is a powerful reminder that the myeloma community remains united by one mission: delivering better outcomes for all patients.
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Vincent Rajkumar retweeted
#mmsm #IMWG26
One important discussion point brought by @VincentRK was to be careful about the assumption that PERSEUS study PFS will be 17 yrs
While outcomes are great with quad based therapies in transplant eligible patients, such modeling need to be taken with grain of salt
Here is why
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