Physician-scientist. Dad. Husband. Associate Professor @yaleibio @yale_labmed. We study host-viral interactions #covid #norovirus @wilenlab.bsky.social
Joined May 2011
- Tweets 1,910
- Following 1,155
- Followers 2,698
- Likes 7,890
81 Photos and videos
Jun 11
From viral immunology to viral video. Great talk by @aryaokten Your Immune System Is an Information Network | Arya Ökten | TEDxYale youtu.be/BXAbfO04kCg?si=UDqh… @YaleIBIO @Yale @Yale_LabMed
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Craig Wilen retweeted
If you didn't catch our previous Nature paper showing how Cas12a2 can selectively kill cells: nature.com/articles/s41586-0…, you have another chance to see this CRISPR enzyme in action, with work we did in collaboration with the Jennifer Doudna Lab: nature.com/articles/s41586-0…
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We’re bringing new capabilities to GPT-Rosalind, a model series purpose-built for life sciences research at enterprise scale.
It brings GPT-5.5’s agentic coding and tool use together with stronger intelligence for drug discovery, analysis, design, and experimental workflows.
openai.com/index/introducing…
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Catalogue entries for more than 100 antibodies sold by the research services and supply company Thermo Fisher Scientific contain images that have apparently been manipulated, according to a pair of science sleuths.
go.nature.com/4wZqGEE
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Craig Wilen retweeted
May 17
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures", but their own internal data.
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Craig Wilen retweeted
May 14
So excited to share our new work beautifully lead by @madisonstrine where we identify new properties of early life T cells. doi.org/10.64898/2026.05.08.…. @YaleMed @YaleIBIO @YalePediatrics
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Craig Wilen retweeted
May 10
A short write-up about the journey of our lab. Starting as T cell immunologists, we stumbled across Wnt signaling in flies and frogs. Worked on colon cancer. Then Nick Barker (left) discovered the gut stem cell and Toshi Sato invented organoids authors.elsevier.com/a/1n3No…
ALT (Photo from lab retreat ~2012)
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Craig Wilen retweeted
🚨 Out today in Cell! @CellCellPress
Path2Space: #AI that predicts spatial transcriptomics (ST) from H&E pathology, enabling spatial biomarker discovery in #BreastCancer at scale.
📄 doi.org/10.1016/j.cell.2026.…
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Craig Wilen retweeted
Mar 27
1/ Thrilled to share a Perspective that summarizes 30 years of work from the many labs studying the human genetic and immunological causes of infectious diseases: doi.org/10.70962/jhi.2026002…
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Craig Wilen retweeted
BREAKING🔔 Our new study is out at @biorxivpreprint. We established a novel animal model for SARS-CoV-2 infection using horseshoe bats, a natural reservoir of SARS-CoV-2-related coronaviruses in nature. Please repost🦇
biorxiv.org/content/10.64898…
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Craig Wilen retweeted
Mar 15
HIV joining the circular RNAs Club ? Welcome ! nature.com/articles/s41564-0…
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Craig Wilen retweeted
Mar 7
Congratulations to @SteitzLab ! 🎉🎉🎉
📣 On Thursday, April 23 at the Joseph B Martin Conference Center we will be hosting our 11th Annual RNA Symposium!
REGISTRATIONS ARE OPEN! eventbrite.com/e/hms-initiat…
Join us as we present Dr. Joan Steitz from Yale School of Medicine with our Lifetime Achievement Award!
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Craig Wilen retweeted
Excited to share an amazing video on the NLRP3 inflammasome pathway generated by talented Ann from the Iwasa lab @janetiwasa @Ann_HuiLiu. It shows the real cryo-EM structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. #cryoem @LeXiao17 Enjoy
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Craig Wilen retweeted
Excited to share our new paper in @CellCellPress with @MarcoRuella, led by @Shan_Liu_
and @PuneethGuru_. CAR T cell therapy loses effectiveness over time due to metabolic exhaustion, but we found a surprisingly simple approach to address it. 👇
cell.com/cell/abstract/S0092…
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Mar 6
Congratulations to Dr. Pena-Hernandez @marioph13 on his outstanding thesis defense today! We couldn’t be more proud! Both the Wilen and Iwasaki labs will miss you. @VirusesImmunity @Yale_LabMed @YaleIBIO
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Craig Wilen retweeted
Feb 28
Increasing evidence that STING has functions beyond DNA viruses. A new study reports that STING restricts influenza infection, independently of IFN. This work complements prior studies that STING prevents infection with diverse RNA viruses.
science.org/doi/10.1126/scie…
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Craig Wilen retweeted
Feb 25
New study from Wade Schulz, MD, PhD (left) & @ThomasDurantMD of @YaleMed in @clin_Chem_ADLM evaluates performance of quantum machine learning algorithm—quantum circuits w/data re-uploading (QC-REUP)—compared to classical machine learning & other QML methods rb.gy/y9mmj6
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Craig Wilen retweeted
New in @JVirology: How does the human norovirus particle assemble?
Particle assembly is facilitated by VP2 acting as a molecular bridge. We also share intriguing features making pandemic HuNoV VP2 unique in structure and sequence. journals.asm.org/doi/10.1128…
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Feb 14
Grea paper. Congrats to the Lee lab @Yale_LabMed
Feb 13
A high-throughput screening system enabled identification of the antigen targets of T cell receptors found in many individuals
science.org/doi/10.1126/scia…
@ScienceAdvances @Yale
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Craig Wilen retweeted
A nice write-up from Nature Immunology about our recent paper!
nature.com/articles/s41590-0…
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