Zach Schafer's Lab @NotreDame. Studying #metabolism, #celldeath, #ECMdetachment, #metastasis, & #cancer. Account maintained by Zach. Views are mine.

Joined May 2018
101 Photos and videos
Pinned Tweet
26 Mar 2024
Grateful to share our most recent paper--just published in @CellReports. The study was led by @NDBios PhD student @Schofield_isle, who will be defending his dissertation later this week. Also want to highlight @NotreDame senior and @NDXCTF athlete @EmmaAlbano4 as a co-author!
Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides dlvr.it/T4fW7f
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15 Nov 2024

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Our latest paper with Joan @BruggeMe is now out @NatureGenetics! We explore hidden mechanisms of BRCA1 hereditary breast cancer using new mouse models, revealing unexpected tumor-like chromatin changes in Brca1-heterozygous normal mammary cells. nature.com/articles/s41588-0…

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1 Nov 2024
Congrats to @cssmity and @NDBios @NDscience @NotreDame PhD student Hannah Gordon on this publication! Excited to see this out!
Microglia are considered long lived, but @cssmity &co show that individual embryonic #microglia die within 3 days after clearing neural debris and are cannibalized by existing microglia, paradoxically leading to additional microglial death #PLOSBiology plos.io/3Aj1JvE
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Microglia can selectively clear neurons, but what else do they eat? @FChrisBennett & @nachoriko explore a #PLOSBiology study showing that #microglia also cannibalize other microglia, followed by microglial necroptosis Primer: plos.io/4f7sXEs Paper: plos.io/3Aj1JvE
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Please RT and help us get the word out. Scott Dixon @sjd956 and I are co-organizing the first @FASEBorg #Ferroptosis conference this summer! Awesome line up of speakers and room for additional short talks! Save the date & come join us July 27 - 31, 2025! 🤩events.faseb.org/event/11797…
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#NASmember Joan Brugge has advanced #breastcancer research in two major ways: through her studies of the processes in breast cancer's initiation and progression, and her explorations of how cellular receptors regulate the intracellular cytoskeleton. #BreastCancerAwarenessMonth
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There is no such thing as a perfect leader. In fact, if someone claims to be a perfect leader, they are probably not even a good leader, as they lack the self-awareness needed to seek out feedback and continue to grow and improve.
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2 Oct 2024
Congrats to Matt on this new role! His deep expertise and thoughtful demeanor was integral in working with many of us in @NDBios to launch a new introductory biology course sequence for @NotreDame students. @ieiatnd is in good hands!!
Congratulations to our founding director, Matt Kloser, on being named the new Hackett Family Director of Notre Dame's Institute for Educational Initiatives (IEI) 👏🏻 @ieiatnd Read more: provost.nd.edu/news/institut…
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20 Sep 2024
Thanks to @bensahralab @clara_peek #notwitternav and @NorthwesternMed @LurieCancer for hosting the #MidwestMetabolism meeting yesterday. Had a great time attending with numerous members of the #SchaferLab @NDBios @NDscience @NotreDame. @LyssiotisLab, next year at @UMich?
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What an excellent meeting. Midwest has the best Metabolism 💪🏼 Thanks to @bensahralab, Nav, & Clara (@NorthwesternMed, @LurieCancer) for hosting. See ya next year in Ann Arbor! @UMich represent 👇🏼〽️ #GoBlue @YatrikShahLab, @DanWahlMD, @DNagrathLab
We are excited to host the Midwest Metabolism Meeting (M3) this week! @LurieCancer @NUFeinbergMed. Join us to attend exciting talks and poster presentations by postdocs and students and a keynote address by Prof. Richard DiMarchi @IUBChemistry cancer.northwestern.edu/even…
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We are excited to host the Midwest Metabolism Meeting (M3) this week! @LurieCancer @NUFeinbergMed. Join us to attend exciting talks and poster presentations by postdocs and students and a keynote address by Prof. Richard DiMarchi @IUBChemistry cancer.northwestern.edu/even…
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16 Sep 2024
Love to see @NDBios @NDScience @NotreDame friends/colleagues @alfmireles and @Felipe_hst on this list!
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14 Sep 2024
Celebrated Father Bob’s inauguration as the 18th president of @NotreDame with colleagues/friends in @NDBios @NDScience. Excited for the future under his leadership!
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6 Sep 2024
Thoughtful piece by @FrezzaLab here---recommended reading for all in science in any career and at any career stage! Thanks for sharing your wisdom Christian.
6 Sep 2024
When I meet other scientists, we more often discuss how to cope with failure rather than to achieve success. So I wrote this piece. I'd love to hear your views. "Uno su mille ce la fa". Rethinking a scientist’s success network.febs.org/posts/uno-s… #FEBSnet
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The University of Notre Dame is hiring a cluster of 5 new Assistant Professors in Neuroscience starting this year, focused on cellular, molecular, or computational neurobiology. Come be a colleague! More information here: apply.interfolio.com/152596 Please share and retweet!

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28 Aug 2024
We recently said goodbye to @Schofield_isle Dr. Jamie Schofield as he moves on to a position with @JNJNews. Prior to his departure, Jamie was selected as the 2024 recipient of the Exemplary Graduate Research Career Award from @NDBios @NDscience . Congrats Jamie, good luck at J&J!
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🥉 BRONZE 2021 biochemistry alum Yared Nuguse finished third in the men's 1500m, earning his first Olympic medal! #ParisOlympics
Yared Nuguse is taking home his FIRST Olympic medal.🥉 #ParisOlympics
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Mark your calendars! The 1st FASEB #Ferroptosis conference, July 27-31 2025! We just posted our preliminary agenda! Spectacular line up and lots of space for short talks / late breaking speakers. Help us get the word out & come join us in 2025! @FASEBorg events.faseb.org/event/11797…
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10 Jul 2024
Fellowship announcement! Congrats to @NDBios @NDScience @NotreDame #SchaferLab graduate student Lauren Young for receipt of a Research Supplement to Promote Diversity in Health-Related Research for our current @theNCI @NCICancerBio award. Congrats Lauren!
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10 Jul 2024
Also, thanks to my friend and colleague @alfmireles for helping us put together a strong application!
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