May 22
Wow!!!! What a time to be practicing as an oncologists (and this will only get better)! Now, we need better strategies for ToxCheck management for all these agents. With all that in mind... Median PFS not REACHED at 7yrs!!!! #lcsm @ALKPositiveinc
2
5
655
May 21
Here is the table we have used during our ToxCheck discussion w/ @MLJohnsonMD2 on BRAF-MEKi.
- Common AEs
- Approved dose/Step down dosing
- Clinical Pearls
#OncTwitter #MedTwitter #lcsm @OncUpdates @OncoAlert
May 20
ToxCheck: BRAF-MEKi in #LungCancer with @MLJohnsonMD2
✅ Encorafenib-Binimetinib
✅ Dabrafenib-Trametinib
Full 🗣️
⭐️ OncBrothers & @OncUpdates Website
⭐️ “Oncology Brothers” podcast
#OncTwitter #MedTwitter @SarahCannonDocs @OncoAlert
5
10
37
5,638
May 20
✅ Encorafenib-Binimetinib
✅ Dabrafenib-Trametinib nomenclature: stem -metinib (MEK inhibitors) -rafenib (BRAF i hibitors) I listened to this Toxcheck podcast in my car to work today. Just awesome 👏 Don’t just focus on horsepower. Primum non nocere! Do no harm
May 20
ToxCheck: BRAF-MEKi in #LungCancer with @MLJohnsonMD2
✅ Encorafenib-Binimetinib
✅ Dabrafenib-Trametinib
Full 🗣️
⭐️ OncBrothers & @OncUpdates Website
⭐️ “Oncology Brothers” podcast
#OncTwitter #MedTwitter @SarahCannonDocs @OncoAlert
1
1
5
1,653
May 20
ToxCheck: BRAF-MEKi in #LungCancer with @MLJohnsonMD2
✅ Encorafenib-Binimetinib
✅ Dabrafenib-Trametinib
Full 🗣️
⭐️ OncBrothers & @OncUpdates Website
⭐️ “Oncology Brothers” podcast
#OncTwitter #MedTwitter @SarahCannonDocs @OncoAlert
8
15
8,926
May 19
Enco-Bini ends up being my preferred combo as well! Better tolerated (will share ToxCheck discussion around this hopefully soon) and more mature data. That said… IO/IO-Chemo is still a viable option from some patients or at the time of progressive disease!
1
4
409
May 15
ToxCheck: Bispecific Antibodies 🗣️ that we use in Multiple Myeloma w/ @hhashmi87 & @myelomatips
✅ Talquetamab
✅ Teclistamab
✅ Elranatamab
✅ Linvoseltamab
Full 🗣️
⭐️ OncBrothers & @OncUpdates Website
⭐️ “Oncology Brothers” podcast
#OncTwitter #MedTwitter #HemeTwitter
7
14
17,575
May 14
Here is the list of drugs that we touched on during our #ToxCheck discussion with @JSabari & #AzamFarooqui on anti-EGFR in NSCLC!
- Dose
- Step down dosing
- Common AEs
#lcsm #OncTwitter #MedTwitter #LungCancer @OncUpdates
May 13
Tox-Check: anti-EGFR drugs we use for mEGFR non-small cell #LungCancer w/ #AzamFarooqui & @JSabari
✅ Afatinib
✅ Osimertinib
✅ Amivantamab Lazertinib
Full 🗣️:
⭐️ OncBrothers & @OncUpdates Website
⭐️ Also on “Oncology Brothers” podcast
#lcsm #OncTwitter #MedTwitter
2
9
30
4,369
Apr 27
Here is the full link to our ToxCheck discussion (conversation around common AEs and clinical pearls on systemic Rx options we use for ColoRectal cancer w/ @RonaYaeger from @MSKCancerCenter
✅ Chemo
✅ VEGFi & Anti-EGFR
✅ BRAFi
✅ TKIs
youtu.be/O3Z2WJYt19U?si=fdxC…
7
20
16,878
Apr 27
ToxCheck: AEs and clinical pearls around systemic Rx options we use for ColoRectal cancer w/ @RonaYaeger:
✅ Chemo
✅ VEGFi & Anti-EGFR
✅ BRAFi
✅ TKIs
Full 🗣️:
⭐️ OncBrothers & @OncUpdates Website
⭐️ Also on “Oncology Brothers” podcast
#OncTwitter #gism #MedX #crcsm
4
16
1,742
14 Dec 2025
This is the table we’ve used (common AEs, black📦warnings, & dose⬇️) during our ToxCheck 🗣️ on ADCs in #LungCancer with @sands_jacob:
1. TDXd: 🫁, Nausea, fatigue
2. DatoDXd: Stomatitis, dry 👀, 🫁
3. TelisoV: Neuropathy
#OncTwitter #MedTwitter #lcsm @OncoAlert @OncUpdates
13 Dec 2025
ToxCheck: AEs for ADCs approved in Lung Cancer & how to manage them with @sands_jacob:
✅ TDXd: HER2
✅ DatoDXd: EGFR
✅ TelisoV: C-MET
Full 🗣️:
⭐️ oncbrothers.com/toxcheck-adc…
⭐️ Also on “Oncology Brothers” podcast
#OncTwitter @OncUpdates @OncoAlert #lcsm
29
63
10,111
13 Dec 2025
ToxCheck: AEs for ADCs approved in Lung Cancer & how to manage them with @sands_jacob:
✅ TDXd: HER2
✅ DatoDXd: EGFR
✅ TelisoV: C-MET
Full 🗣️:
⭐️ oncbrothers.com/toxcheck-adc…
⭐️ Also on “Oncology Brothers” podcast
#OncTwitter @OncUpdates @OncoAlert #lcsm
2
10
28
15,548
11 Dec 2025
ToxCheck: AEs for PI3K inhibitors & how to manage them when treating HR breast cancer w/ @Neil_Iyengar & #DrGallagher
✅ Inavolisib
✅ Capivasertib
✅ Alpelisib
Full 🗣️:
⭐️ oncbrothers.com/pik3ca-toxch…
⭐️ Also on “Oncology Brothers” podcast
#OncTwitter @OncUpdates @OncoAlert
1
9
29
16,913
13 Nov 2025
ToxCheck: AEs for ROS1 inhibitors & how to manage them when treating ROS1 fusion positive NSCLC w/ @Latinamd
✅ Crizotinib
✅ Enterectinib
✅ Repotrectinib
✅ Taletrectinib
Full 🗣️:
⭐️ oncbrothers.com/ros1-toxchec…
⭐️ Also on “Oncology Brothers” podcast
#OncTwitter @OncUpdates
1
8
29
17,537
10 Nov 2025
ToxCheck: AEs for TKIs & how to manage them when treating CML w/ @FadiHaddad_MD #DrOnyeeChan
✅ Imatinib
✅ Ponatinib & Asciminib
✅ Dasatinib, Bosutinib, Nilotinib
Full 🗣️:
⭐️ oncbrothers.com/tki-toxcheck…
⭐️ Also on “Oncology Brothers” podcast
#HemeTwitter @OncUpdates
5
29
14,399
17 Oct 2025
We now have more data on adj CDK4/6i at #ESMO25 we’ll continue to use these Rx in metastatic settings as well. This is the table we’ve used (AEs doses) for #Ribociclib #Abemaciclib, #Palbociclib w/ @DrSGraff for our #ToxCheck 🗣️
#bcsm #OncTwitter @OncoAlert @OncUpdates
16 Oct 2025
At #ESMO25 we’ll see mature data on CDK4/6 inhibitors. We are using these drugs more & more in our 🏥! With @DrSGraff in #ToxCheck 🗣️ we reviewed Palbo, Ribo & Abema AEs management
Full 🗣️
⭐️ Oncbrothers.com/cdk-toxcheck…
⭐️ “Oncology Brothers” podcast
#OncTwitter @OncUpdates
9
53
138
23,161
16 Oct 2025
At #ESMO25 we’ll see mature data on CDK4/6 inhibitors. We are using these drugs more & more in our 🏥! With @DrSGraff in #ToxCheck 🗣️ we reviewed Palbo, Ribo & Abema AEs management
Full 🗣️
⭐️ Oncbrothers.com/cdk-toxcheck…
⭐️ “Oncology Brothers” podcast
#OncTwitter @OncUpdates
11
26
26,322
7 Aug 2025
ToxCheck series: Common AEs and how to manage them when using TKIs for RCC with @montypal
✅ Cabo, Len, Axi
✅ Tivozanib
✅ Belzutifan
Full discussion:
⭐️ oncbrothers.com/toxcheck-rcc…
⭐️ Also on the “Oncology Brothers” podcast
#gusm #OncTwitter @OncUpdates
1
11
44
58,240
21 May 2025
This is the table we’ve used (common AEs & dose⬇️) for Afatinib, Osimertinib, and Amivantamab Lazertinib #ToxCheck 🗣️ on commonly used anti-EGFRs in mEGFR NSCLC w/ @GlopesMd
#lcsm #OncTwitter #MedTwitter
21 May 2025
ToxCheck series: Common anti-EGFR drugs we use for mEGFR non-small cell #LungCancer w/ @GlopesMd
✅ Afatinib
✅ Osimertinib
✅ Amivantamab Lazertinib
Full discussion:
⭐️ oncbrothers.com/egfr-toxchec…
⭐️ Also on the “Oncology Brothers” podcast
#lcsm #OncTwitter @OncUpdates
3
25
84
17,697
21 May 2025
ToxCheck series: Common anti-EGFR drugs we use for mEGFR non-small cell #LungCancer w/ @GlopesMd
✅ Afatinib
✅ Osimertinib
✅ Amivantamab Lazertinib
Full discussion:
⭐️ oncbrothers.com/egfr-toxchec…
⭐️ Also on the “Oncology Brothers” podcast
#lcsm #OncTwitter @OncUpdates
1
22
39
28,767
20 May 2025
Just wrapped up ToxCheck discussion (will share this soon) on this topic/class of meds… Afatinib, Osimertinib, and Ami/Laz… side effects from the combo are not trivial!
2
152