🚨Super-exciting work from our most creative 🪄physician-scientist 👨⚕️👨🔬 @MarcHilmi 🇫🇷 from #sPARKlab 🧪 & @schoenfeld_j 🧑🔬 @MckerrowWilson @bengrbm spearheading ⏩the multi-omic analyses in Precision Immunotherapy #POLAR @MSK_DeptOfMed @PICIatMSK @CpcrMsk @MSKCancerCenter 🇺🇸
Getting to the core immune biology of the longitudinal tumor and blood TCR at single cell and spatial level.
🔗nature.com/articles/s41591-0… @NatureMedicine
Invigorating 🔥pre-existing Tumor-Infiltrating Expandable (TIE) T cell clonotypes in exceptional responders with dual PARP-PD-1 blockade in HRD PC
Fascinating story of #spatialTCR offering deep and orthogonal insight from genomically the most ☝️immunogenic 🧪subset of #pancreaticcancer
@CentralParkWMD @TheVinodLab @xrtGenomics @dana_peer @ciacobu @EileenMOReilly
@OncoAlert @oncodaily @OncoDailyGI @OncBrothers
@NatPancFdn @PanCAN @lustgartenfdn
Apr 23
Just back from @AACR and honored to present our POLAR translational work led by the best mentors ever @CentralParkWMD @EileenMOReilly @ciacobu
Using single-cell, spatial transcriptomics & TCRseq, we dissect durable response vs rapid progression in PDAC @MSKCancerCenter
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Happy to see this great study by @LisaSudmeier out. Detailed analysis of CD8 T cell infiltration of brain mets using spatialTCR/Transcriptomics, spectral flow, and scRNAseq. cell.com/cell-reports-medici…
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