🦠 Patient Zero @LongCovidLabs

Joined April 2009
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Pinned Tweet
10 Jan 2025
Can we coordinate our way to a cure for Long COVID? 🧵
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Rohan retweeted
Dr. Tim Henrich presented new findings surrounding long term persistence of SARS-CoV-2 proteins & RNA in Long COVID gut tissue at PolyBio’s recent Spring symposium. “We actually see [gut viral persistence] in both areas, the epithelium—which turns over every several days to week—to the lamina propria where you have long-lived myeloid immune cells… suggesting there may even be replication in some individuals,” said Henrich. Using a highly sensitive method of detecting viral RNA, “around 20-25% of the time, we see detection… all the way up until 3-4 years after initial infection” in Long COVID patients.
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Rohan retweeted
People who tested positive for #COVID have a higher risk of being diagnosed with other infections in the following months. This has been shown for years and hundreds of publications in the topic. Covid has an impact on the immune system we still don't fully understand.
Why Covid could be to blame for the rise in deadly meningitis, according to scientists - and the early symptoms of the disease that patients must act on trib.al/XW4xOX8
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Apr 2
Again and again we see viruses linked to dementia and neurodegenerative disorders. This new study (n>160,000) showed high dose flu vaccines reduces Alzheimer's dementia.
We've seen the Shingles vaccine is linked with reduced risk of Alzheimer's and dementias in 4 large natural experiments. Today, the potential of high-dose flu vaccines vs standard dose for the same in a large retrospective age 65 cohort [N>160,000). More pronounced in women (like Shingles vaccine) neurology.org/doi/pdf/10.121…
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Apr 2
What about dementia, specifically? We may need to wait for researchers with access to large epidemiological datasets to find out.
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Apr 2
If anyone is working with large datasets that might be relevant here, please reach out to @longcovidlabs - we'd love to help support this research.
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Mar 2
One of those "hand-washing reduces infections" paradigm shifts - the role of viruses in accelerating aging is still not fully acknowledged. I predict COVID-19 will, unfortunately, be a prime catalyst for this.
During their lives, centenarians rarely get sick. New paper with 1,400 subjects finds a history of infections (pneumonia, herpes, UTIs) associates with earlier frailty. The authors speculate that obesity makes people more susceptible & that viral infections may accelerate aging
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Mar 2
Fascinating. May explain the micro-dosing GLP-1 protocols for Long COVID - we know there is significant dysautonomia and vagus nerve dysfunction.
Ozempic and GLP-1 cause weight loss via the vagus nerve. In people whose vagus nerve was surgically cut (below the diaphragm, not in the neck), GLP-1 did not reduce food intake or accelerate metabolism. These drugs work through the vagus, in ways we still do not fully understand.
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National Taiwan University researchers analyzed data from over 97 million individuals and found that COVID-19 is linked to a 49% higher risk of developing autoimmune diseases. The risk rose after severe infection but dropped by 44% in vaccinated people. link.springer.com/article/10…

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10 Dec 2025
A new RECOVER study of 6.4M health records shows Long COVID risk has not decreased from 2020–2024. Incidence stayed stable across variants, reinforcing Long COVID as an ongoing public health priority. Read the study: doi.org/10.1093/cid/ciaf046
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8 Nov 2025
3 years after antivirals and monoclonal antibodies cured my long COVID symptoms. Science can feel painfully slow. But hats off to the scientists, doctors and companies pushing the rock up the hill. We need a global Moonshot for Long COVID, now.
New cases series: @Invivyd's Pemgarda (Pemivibart) monoclonal antibodies shown to reduce PEM in three heterogenous Long COVID cases Is this the first evidence published in a scientific journal of COVID-specific mAbs treating PEM in Long COVID?
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Urine tells the story of #LongCOVID: ➡️ New study identifies a molecular fingerprint for #LongCOVID (PASC) — using just a urine test. ➡️ Researchers found 195 urinary peptides that can accurately distinguish Long COVID patients from healthy and ME/CFS controls (AUC > 0.95). 1/
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10 Oct 2025
Long COVID is now the most common childhood disease in the U.S. -- so predictable, and so sad.
8 Oct 2025
PBS: What do you want people who haven’t been affected by LC to know about this community? @meighanstone: Americans may feel like the pandemic is over.. but even in just last few months we saw the announcement that #LongCovid is now the most common childhood illness in the US
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16 Oct 2025

It’s a slow-moving spiral: first their health, then their grades, then their future. Those for whom Covid looms very present are feeling forgotten, subject to pervasive skepticism and a kind of cultural fatigue when it comes to their illness. 🔗 rollingstone.com/culture/cul…
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11 Aug 2025
Diagnosis and characterization of people with #MECFS (vs controls) using circulating cell-free RNA, indicative of immune system dysfunction and pro-inflammatory cytokine signaling pnas.org/doi/10.1073/pnas.25…
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🔬New @BhupeshPrusty paper breakdown - very cool paper: The study finds that people with ME/CFS & Long COVID have antibodies in their blood that may directly interfere with mitochondria (how human cells create energy and regulate inflammation) In simple language all findings 🧵
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