Show me your neighbors and I'll tell you who you are - the single cell transcriptomics edition. Statistician, postdoc @broadinstitute, @MIA_at_Broad, @TheHDSR
We can often reconstruct a certain layer of information from single-cell data, like their spatial configuration or trajectory, but what can we learn when we peel that layer off? What else is encoded? SiFT is out @NatureComms, Led by @zoe_pirannature.com/articles/s41467-0…@HebrewU
Interested in uncovering biological processes in single-cell data? Check out SiFT, featured in @NatureComms. SiFT peels off layers of known variability and allows studying previously unexplored bio signals. Try it yourself: sift-sc.readthedocs.io. w/ @mor_nitzan
Artwork: Reo F.
Interested in uncovering biological processes in single-cell data? Check out SiFT, featured in @NatureComms. SiFT peels off layers of known variability and allows studying previously unexplored bio signals. Try it yourself: sift-sc.readthedocs.io. w/ @mor_nitzan
Artwork: Reo F.
Consider submitting your work to the Machine Learning for Genomics Explorations (MLGenX) workshop at @iclr_conf ! Join us to unite the worlds of #MachineLearning & #Genomics 🧬
⏰Submission deadline: February 4, 2024 (AOE).
📢🚨 Excited to announce the Machine Learning for Genomics Explorations (MLGenX) workshop at @iclr_conf 2024.
⏰ Submission deadline: February 4, 2024 (AOE).
🔗 Call for papers: mlgenx.github.io
🗓️ Date: May 11, 2024.
MIA Spring ‘23 Speaker Series
⏰ April 5, 9AM EST
💬 Lucy Colwell, Benjamin Sanchez-Lengeling @beangoben
💡Primer: Intro to machine learning for molecules
💡Seminar: ML to predict protein function from sequence ...
📬 Join our mailing list to get the talk link!
#BroadMIA
Join my group at Genentech and follow your passion for single-cell tumor dynamics!
Both experimental and computational positions available.
Apply below:
Cancer Single-Cell Genomics: lnkd.in/eR2eCqPd
Computational Biology: lnkd.in/e7TeHsXg
So excited for @oana__ursu and @_bunnech’s talks this Wednesday at #BroadMIA! Tune in at 9AM EST to learn about computational approaches to study single-cell state transitions and responses to perturbation!
📢 Nov 16
⏰ 9AM EST
💬 Oana Ursu @oana__ursu
💡 Primer: Analytical challenges and opportunities for studying cell state transitions at single cell level
⏰ 10AM EST
💬 Charlotte Bunne @_bunnech
💡 Neural Optimal Transport for Inferring Single-Cell Responses to Perturbations
📢 MIA Fall ‘22 Speaker Series
⏰ Sept 21, 9AM EST
💬 David Kelley @drklly
💡 Primer: Gene expression prediction from DNA sequences
⏰ Sept 21, 10AM EST
💬 Carl de Boer @CarldeBoerPhD
💡 Using deep learning regulatory models and random DNA for evolutionary inference
#BroadMIA
📢 MIA Fall ‘22 Speaker Series
⏰ Sept 21, 9AM EST
💬 David Kelley @drklly
💡 Primer: Gene expression prediction from DNA sequences
⏰ Sept 21, 10AM EST
💬 Carl de Boer @CarldeBoerPhD
💡 Using deep learning regulatory models and random DNA for evolutionary inference
#BroadMIA
I made an accessibility map of #Neurips2022. The country is marked in red if its resident can not get appointment in time from getting accepted to the conference (76 days).
Science is unbearable if you hold off on celebrating until the publication of a big paper. The more we enjoy the process, the happier we are..
Celebrate the interesting group meeting, the preparation of a new presentation, the new technique, & the progress our friends are making.
📢 MIA Fall ‘22 Speaker Series
⏰ Sept 14, 9AM EST
💬 Martin Jankowiak
💡Primer: An Introduction to Bayesian Variable Selection
💡Seminar: Applications of Bayesian Variable Selection to Bioinformatics
📬 Join our mailing list to get the talk link!
#BroadMIA
Csiszar f-divergences (KL, TV, Hellinger, Chi2, etc) are all closely related and define similar topologies. Wasserstein distance in contrast requires upper/lower bounds on the spacing between the points. Nice review by Gibbs and Su. en.wikipedia.org/wiki/F-dive…math.hmc.edu/~su/papers.dir/…
Finally, we added new example datasets! You can access SeqFISH, MERFISH, Slide-seqV2, Visium, Mibi-tof, 4i, IMC datasets through the Squidpy API to try out all the new functions!
squidpy.readthedocs.io/en/st…
Thanks to @macosko@AleksGoeva for providing pre-processed Slide-seqV2 data!
We worked for years to profile human dopamine neurons at scale; @abdul_squared cracked it. @tkam80 revealed the full diversity of DA neurons in the substantia nigra, and their relative vulnerabilities to degeneration in Parkinson's disease.
biorxiv.org/content/10.1101/…
The Early Career Board of @TheHDSR is a most creative board I have ever worked with. My last invitation to @AleksGoeva : “Feel free to be innovative re the format, and surprise me! :-)”. They did, in a delicious way! Wondering what’s cooking next…(no pressure, Aleks & all :-))