Dirk Brenner's research group in Luxembourg @LIH_Luxembourg and @uni_lu. We study #immunology, #immunometabolism in inflammation and cancer.

Joined May 2018
44 Photos and videos
Pinned Tweet
We made it on the cover of @Cell_Metabolism! Incredible artwork & research by Lynn Bonetti @LIH_Luxembourg, our lab & collaborators. ROS, glutathione, mitochondria, ETC, Th17 cells, infections & gut health! Check it out @FnrLux @uni_lu @science_lu @ImmunoMet @ImmunoMetEurope
12
22
164
12,997
Brenner Lab retweeted
Excited to share our new work uncovering a previously unknown mechanism identifying ANKIB1 as the E3 ligase that writes a critical new letter of the ubiquitin code central for immune signalling: K11-linked ubiquitin nature.com/articles/s41556-0…
1
23
58
8,739
🚨 Only 10 days left! Join us at EIMN2026 | 2nd European Immunometabolism Conference 📍 Luxembourg | 🗓 June 10–12, 2026 👉 Register & submit your abstract by March 1 👉 3 days of cutting-edge immunometabolism, real discussion & strong networking 🔗 eimn2026.lu/en/
4
8
604
New @Cell_Metabolism Spotlight written by our lab! How do macrophages recycle what they eat? We highlight the study by Lesbats et al. showing how phagocytosed bacteria fuel host metabolism Read the Spotlight: sciencedirect.com/science/ar… The great article: nature.com/articles/s41586-0…

1
20
97
6,886
Brenner Lab retweeted
Check out the comments of Professors Dirk Brenner @Brenner_Lab and Bart Everts @EvertsBart on this paper "Blocking lactate: kick T cells when they are down" journals.lww.com/immunometab… Welcome to read!
I've been on a Twitter moratorium for the last week given the.. news, but I'm happy to announce a new story from our group @NatImmunol describing a metabolic sensitivity of exhausted T cells to lactic acid in tumors! 1/ nature.com/articles/s41590-0…
4
16
4,186
Just back from an amazing CANBIO2 retreat! Proud that my PhD student Sarah Alhamouieh won the Best Talk Prize, awarded by: Jorge Moscat & Maria Teresa Diaz-Meco Conde (Cornell) & @Thomas_Helleday (Karolinska). Great science, discussions&networking!Huge thanks to the organizers!
10
494
Excited to share our latest review: "Navigating the metabolic landscape of regulatory T cells: from autoimmune diseases to tumor microenvironments". Great work by my PhD students Janika Härm & Yu-Tong Fan @LIH_Luxembourg. sciencedirect.com/science/ar…
1
3
33
2,005
Brenner Lab retweeted
2 weeks left to register for #Mito25 in the Dominican Republic. Amazing program and speaker lineup 🌴🔬🧪☀️
@DavidFinlayTCD we are looking forward to your presentation at #Mito25 this coming February☀️There is only 2 WEEKS left to register, so please RT to let your followers know limited spaces remain to join us in the Dominican Republic! 🇩🇴 Register here➡️bit.ly/3zPBufN
1
1
13
1,962
Brenner Lab retweeted
Check out our latest work, hot off the press @MolecularCell
Novel Selenium Carrier Protein Regulates Ferroptosis in Cancer and Brain🧫 👉Read more: t1p.de/kr969 Scientists at #HelmholtzMunich have uncovered the selenium carrier protein PRDX6 as a critical player in #ferroptosis - a cell death process that holds promise for #cancer and neurodegenerative disease #therapies. 💡This study reveals PRDX6’s dual role as both a regulator of #OxidativeStress and a selenium transporter, essential for maintaining cellular defenses against damage. 🌟Implications: Targeting PRDX6 may increase sensitivity to ferroptosis in cancer cells, a potential new strategy against therapy-resistant #tumors. In neurodegenerative diseases like #Alzheimer’s, PRDX6 could help protect neurons by supporting selenoprotein production, opening doors for therapeutic advancements. @Conrad_Lab @Ferroptosis2306 @Ferroptosis1 #CancerResearch #NeurodegenerativeDisease #Selenium #MultipleSclerosis
6
30
2,396
Brenner Lab retweeted
Supported by @ImmunoMetEurope, @ImmunoMetNet, @BSI_immunomet, @ImmunoMet @immunemet, @SocietyEuropean and others working on immunometabolism, the aim of the Immunometabolism journal @Immunometaboli2 is to further grow and to become THE go-to journal in this exciting field
Our journal welcomes short commentary articles to put recently published high-impact work in a broader perspective. 🥳🥳🥳Interests in writing a commentary, contact our EiC Professor Jan Van den Bossche​ @immunometlab and the EB member Professor Sarah Dimeloe @SarahDimeloeLab
1
9
23
2,943
Brenner Lab retweeted
Check out Professor David K. Finlay @DavidFinlayTCD from Trinity College Dublin et al's comments on this paper. journals.lww.com/immunometab…
We made it on the cover of @Cell_Metabolism! Incredible artwork & research by Lynn Bonetti @LIH_Luxembourg, our lab & collaborators. ROS, glutathione, mitochondria, ETC, Th17 cells, infections & gut health! Check it out @FnrLux @uni_lu @science_lu @ImmunoMet @ImmunoMetEurope
7
19
3,997
Many thanks to @DavidFinlayTCD and SimonO’Shaughnessy for highlighting our study, and to @Immunometaboli2 for showcasing this work! Exciting to see oxidative stress in gut Th17 cells inspiring further discussions!
Check out Professor David K. Finlay @DavidFinlayTCD from Trinity College Dublin et al's comments on this paper. journals.lww.com/immunometab…
3
18
2,553
Brenner Lab retweeted
A fantastic day celebrating the 40th anniversary of the discovery of the TCR. Check out this T cell speaker photo which includes co-discoverers Tak Mak and Mark Davis. Thanks @UofT, @uoftmedicine, @ImmunologyUofT, @thePMCF for your support.
4
34
212
24,645
Brenner Lab retweeted
Super excited to share my PhD work, out now in @Nature. Here, myself, @lynchielydia, and all my wonderful co-authors explored the link between circadian rhythms, energy homeostasis and innate T cell function. A thread: 🧵 nature.com/articles/s41586-0…
11
49
311
32,709
Stellar moments in immunology: Celebrating 40 years since Tak Mak & Mark Davis discovered the T cell receptor with legends like Jim Allison, Carl June, Philip Greenberg, & our Mak Lab. This breakthrough reshaped science & patient treatment—why no Nobel prize yet? @ScienceAcad_swe
16
773
Brenner Lab retweeted
Late registrations are still possible!
2
1
290
Brenner Lab retweeted
Ready for #DC2024Barcelona? We have ahead of us 4 fascinating days to share new data & discussions and to boost basic & translational research on #dendriticcells 25 top🌍speakers, 46 short talks, 200 posters, >300 attendees! support by @SEinmunologia @SCImmunologia @EuMacDcSoc
3
14
59
15,109
Great that you have been here with us in Luxembourg!
10 Oct 2024
Great to join 30th ECDO. Thanks for the kind invitation from @Brenner_Lab. Amazing meeting, food and live band. Of course, sciences and friends! @MMittelbrunn @AgostinisLab @KatjaSimon4 !
1
472
Brenner Lab retweeted
And after listening caspases discoverer Prof. Junying Yuan and former colleague Wei Xie talks, we say goodbye to Luxemburg with new ideas and contacts to be made!!!! Thanks @Brenner_Lab for such a great conference!!! #ECDO24
1
5
301
Honored to have had the chance to organize the 30th Anniversary @ECDOorg Meeting together with Michael Heneka in Luxembourg @lcsb_uni_lu! Amazing community, inspiring science! It was fantastic to catch up with the field! Big thanks to all speakers & everyone who contributed!
1
6
27
4,198