The Coller Lab uses modern approaches to investigate #quiescence, cell cycle control, #autophagy, and #cancer. Official account managed by the lab members.
Joined November 2021
- Tweets 63
- Following 186
- Followers 125
- Likes 293
28 Photos and videos
Coller Lab retweeted
May 11
⭐️Check out the Perspective on cellular neighborhoods in cancer by @LichunMa, @KaiTanLab1 & co
🔗nature.com/articles/s43018-0…
Part of our Series on Tumor Heterogeneity and Plasticity:
nature.com/collections/gfbbj…
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Coller Lab retweeted
Check out the latest from @Rachel_E_Savage, @JD_Buenrostro and many collaborators as part of the @IGVFConsortium
It takes two (transcription factors) to tango
Transcription factor collaboration enables precise T cell state engineering
tinyurl.com/tcelltfs
Excited to share our preprint with @JD_Buenrostro, @cgersbach, and an incredible team of collaborators as part of @IGVFConsortium
🧵
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Coller Lab retweeted
⭐️Don't miss this Review published @NatureCancer
as part of our Series on Tumor Heterogeneity and Plasticity
'Heterogeneity and plasticity of cancer-associated fibroblasts'
✒️By Ruth Scherz-Shouval, Mara Sherman and co-authors
🔗nature.com/articles/s43018-0…
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Coller Lab retweeted
Feb 25
(1/5) How does glioblastoma maintain its immense heterogeneity? 🧠 Two new companion papers from the Bhaduri Lab @UCLA now on @bioRxiv offer a lineage-resolved view of GBM hierarchies. Let’s dive in! 🧵👇
biorxiv.org/content/10.64898…
biorxiv.org/content/10.1101/…
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Coller Lab retweeted
Jan 30
We are excited to release a single-cell and spatial 3D epigenomic atlas of developing human basal ganglia and inhibitory neurons, part of our BICAN effort in collaboration with @lab_paredes @jernst98 @emukamel @CEpigenomics @bpasaniuc
biorxiv.org/content/10.64898…
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Coller Lab retweeted
Excited to share a recent publication from the lab. Daniel Benjamin & Jengmin Kang led the study of the allocation of resources to survival over reproduction in stem cells during aging. #EvolutionaryTradeOffs #SurvivorshipBias
science.org/doi/10.1126/scie…
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Coller Lab retweeted
H4K20me3 and CTCF act reciprocally at TAD boundaries to regulate cell state transitions biorxiv.org/content/10.64898… #biorxiv_cellbio
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Jan 26
We are so happy that Michael Cheng, a former undergraduate researcher in the lab and now a bioinformatics graduate student at @UCLA , will be defending his thesis this week (Wednesday at 1 pm; in person and on zoom). All the best, Michael!
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Coller Lab retweeted
10 Nov 2025
🆕🎧 New Podcast: The founding of PG is discussed in interviews with Drs. AW Cowley, Jr., B Joe, and HA Coller. These interviews were organized and conducted by @AkinolaTosinS.
Listen at ow.ly/L0MQ50Xok2H. Read the article at ow.ly/Vrxx50Xok2G.
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New @NatureGenet review from our NIH SenNet @sennetresearch OMICS WG co-led by @shenglilab
We share practical considerations for identifying, characterizing & spatially mapping #CellularSenescence, plus computational #multiomics insights!! nature.com/articles/s41588-0…
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Coller Lab retweeted
11 Oct 2025
Years ago we tried to model cancer-associated fibroblast (CAF) subtypes in vitro, but gave up because only the proliferative subtype survived culture (duh!). This study could change all that: Perturb-seq with CRISPRa of 1,836 TFs induces diverse fibroblast states in vitro(!). 👏
10 Oct 2025
Fantastic work by @thenormanlab in @NatureGenet
Recreating fibroblast diversity in vitro by activating transcription factors
Demonstration of the power of CRISPRa Perturb-Seq to deregulate TF expression in fibroblasts (Function!)
nature.com/articles/s41588-0…
nature.com/articles/s41588-0…
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Coller Lab retweeted
10 Oct 2025
A new bridge recombination edit just dropped! 👀
9 Oct 2025
Why does the naked mole rat have the longest lifespan and healthspan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
science.org/doi/10.1126/scie…
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Coller Lab retweeted
Dr. Hilary Coller (@CollerLab) discussed her latest research on how epigenetic patterns can predict cancer outcomes more accurately than traditional markers. Her pan-cancer model reveals targetable epifactors across five tumor types.
Watch the talk here: bit.ly/4jEAMTU
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Coller Lab retweeted
14 Apr 2025
Join us for our next seminar with Dr. Hilary Coller of @UCLA! ➡️
youtube.com/watch?v=3bh0M98x…
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Coller Lab retweeted
23 Feb 2025
Less than one month away from abstract submission deadline for the 2025 GRC/GRS Genome Architecture meeting at the beautiful beach in California. Don't miss it!
20 Jan 2025
Chromatin folks: don't miss GRC/GRS Genome Architecture in Cell Fate and Disease, June 15-20 2025 Ventura, CA. Registration deadline: Mar 18, 2025. grc.org/genome-architecture-…
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19 Feb 2025
Kaiser is going to defend this doctoral thesis next week (Thursday, February 27th) at 9 AM in 158 Hershey Hall. Everyone is welcome to attend.
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Coller Lab retweeted
27 Jan 2025
In this review for our focus issue on patterns in molecular biology, @LuLaboratory explores how metabolites and metabolic enzymes regulate chromatin and histone modification patterns, highlighting the crosstalk between the metabolome and the epigenome.
cell.com/molecular-cell/full…
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Coller Lab retweeted
27 Jan 2025
CTCF stall DNA 🧬 loop ➰ extrusion by cohesin - but exactly how it pulls this off is a 'mechanistic mystery' (to cite
@Anders_S_Hansen , Nucleus, 2020). We just preprinted 📜 a new study @biorxivpreprint that provides some answers to this enigma: tinyurl.com/3r2a4ux2
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9 Jan 2025
Our new review on "Transcription factor networks in cellular quiescence" is now published in @NatureCellBio. Thanks to the reviewers and the editor for the great suggestions and comments. Read here: rdcu.be/d5JFq nature.com/articles/s41556-0…
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13 Dec 2023
Congratulations to our graduate student, Kaiser, on his amazing talk at the MCDB retreat. Woot woot 🎉
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