Joined March 2021
- Tweets 103
- Following 209
- Followers 570
- Likes 532
12 Photos and videos
Hite Lab retweeted
20 Nov 2024
OK, I’ll bite. We, as scientists, believe our work has value to society. Enough value that we ask for funding from taxpayers and philanthropists. We should be able to justify this value.
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Hite Lab retweeted
9 Sep 2024
Our work on human urate transporter is out @cell_res. @YaxinDai
single-handedly drove this project, which revealed the transport and drug mechanism of URAT1. We are grateful for the tremendous support from @StJudeStructBio
nature.com/articles/s41422-0…
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Hite Lab retweeted
8 Aug 2024
Metabolic regulation of the hallmarks of stem cell biology by Jackson (@__btjackson) and Finley (@lydfinley)
hubs.li/Q02JJ03D0
Collection highlight from @CellStemCell
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Hite Lab retweeted
8 Jul 2024
New work from our lab’s genomics guru @ArtemAKhan with @egamazon. Artem generated a new platform for metabolic gene discovery and identified the mitochondrial choline transporter. @RockefellerUniv @NatureGenet nature.com/articles/s41588-0…
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Hite Lab retweeted
10 Jun 2024
Very grateful to give a webinar for BRIC on June 18th Tuesday, 11am KST (or June 17th Monday 10pm EST!) about my recent work on the high-affinity choline and ethanolamine transporter, FLVCR1. ibric.org/bric/webinar/acade…
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Hite Lab retweeted
8 Jun 2024
Our newest preprint identifies a role for p53 in balancing nutrient supply and demand by enabling phospholipid headgroup recycling 1/
8 Jun 2024
p53 enables phospholipid headgroup scavenging biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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Hite Lab retweeted
22 May 2024
Very grateful that I am invited to give a webinar for ASBMB Lipid Research Division on May 29th, 12-1pm EST. You can register to attend the webinar via the ASBMB website below. Looking forward to meet and discuss research with everyone!
asbmb.org/meetings-events/re…
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Our collaboration with @WillPPK on NOX5 is out. We captured NOX5 in different activation states, and used MD simulation to explore the initiation of electron transfer. An unexpected Zn finger was also identified that is critical for function. nature.com/articles/s41467-0…
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Nature research paper: Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 go.nature.com/4dpuKEH
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Hite Lab retweeted
1 May 2024
Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 @nature
rdcu.be/dGpw6
Congratulations @HiteLabMSKCC @MSKCancerCenter!!
My favorite part: residues specifying Etn vs Cho uptake. Potential clues for evolution of nutrient uptake programs?
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Hite Lab retweeted
2 May 2024
Excited to share our study on a high-affinity choline and ethanolamine transporter, FLVCR1, published today at Nature. I am grateful for my doctoral advisor ,@HiteLabMSKCC , my co-authors and collaborators, @TimCKenny, @ArtemAKhan, and @KivancBirsoy. doi.org/10.1038/s41586-024-0…
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3 May 2024
Excited to share our recent study Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 published this week @Nature led by amazing @Yeeun_Jecy_Son in collaboration with @TimCKenny @ArtemAKhan @KivancBirsoy
@MSKCancerCenter
nature.com/articles/s41586-0…
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3 May 2024
Structures of choline- and ethanolamine-bound FLVCR1 revealed that the metabolites differentially bind to a common transport site, which enabled identification of mutants that uncouple choline and ethanolamine transport.
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3 May 2024
Full text link: rdcu.be/dGpw6
Congratulations to all of the authors and to @RosemaryJCater @pippomancia and colleagues for their identification of the related FLVCR2 as the blood brain barrier choline transporter, published along side our paper @Nature
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Hite Lab retweeted
20 Nov 2023
Authors from @MSKCancerCenter: @HiteLabMSKCC, @labnavid and @VinaySapuru report structures of IP3 receptor with insights into the biphasic dependence on Ca2 for channel activity.
nature.com/articles/s41467-0…
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31 May 2023
Congratulations James! Well deserved.
30 May 2023
BREAKING: Congratulations to now Associate Professor James Letts @LettsScience for his promotion with tenure. @ucdavis is lucky in having you on the faculty.
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25 Apr 2023
Exciting work from @TimCKenny and @KivancBirsoy identifying FLVCR1 as a mammalian choline transporter! Congratulations to everyone involved in this fun project!
25 Apr 2023
Our (now published) work identifying the major mammalian choline transporter by fantastic @TimCKenny @RockefellerUniv sciencedirect.com/science/ar…
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17 Mar 2023
Congratulations @SteveBrohawn and @kerndm on the new story! Really exciting to how much you have been able to learn about the heteromeric channels and their regulation by lipids.
17 Mar 2023
Great to see our story led by @kerndm on LRRC8A:C volume regulated anion channels in its final form! Lots of new data since the preprint including structures of a mutant that disrupts lipid block of the pore to activate the channel rdcu.be/c7MWW
nature.com/articles/s41594-0…
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Hite Lab retweeted
5 Jan 2023
After a pandemic hiatus, @BhabhaEkiertLab and I are pleased to organize the next iteration of the NY Area cryo-EM meeting, April 19, 2023 at Rockefeller! See details in the flyer below. Please RT, and apply if you are interested: forms.gle/k6kG9ShC8DKej5357
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