Pancreatic cancer is most often caught late. On the latest PancChat, Dr. Ray Wadlow breaks down who should be screened, what genetic mutations to know about, and how the @PrecedeStudy is working to change early detection at a global scale.
Listen: youtu.be/LlaPFCDYz28
Among patients with clinically staged T1 ampullary cancer, more than two-thirds were upstaged to a higher pathologic T stage and nearly half were found to have nodal disease at resection. journals.lww.com/annalsofsur…
🆕🗞️Pancreas cancer & #KRAS revolution updates continue. We treated last patient Nov 2024.
📚🧬KRAS Vaccine💉
While ITT DFS wasn’t significant, 2 signals emerge👇🏽:
✔️R0 resection☢️
✔️mKRAS-T-cell responders🔴
➡️👟Gearing up for phase-3.
💭@OncoAlert
🔗globenewswire.com/news-relea…
Today in @NatureNano, we report an all-RNA lipid nanoparticle (LNP) system for efficient in vivo prime editing (PE). We identify bottlenecks in transient prime editor delivery, develop a workflow for LNP optimization, and use it to rescue a mouse model of phenylketonuria.
drive.google.com/file/d/1-rP…
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Who is high-risk for pancreatic cancer? Oncologist Dr. Matthew Yurgelun explains high-risk populations and what steps to take if you meet the criteria. bit.ly/3r82KSD
Learn more about the relationship between diabetes and pancreatic cancer, understand who might be at risk, and find out what to do if you are at risk. letswinpc.org/diabetes/
After you are diagnosed, your oncologist will discuss treatments. Learn more about the different types of chemotherapy, surgery, and radiation used to treat pancreatic cancer. bit.ly/3RDYvcv
Marla Schreffler tenía la sensación de que algo no estaba bien, aun después de que le diagnosticaran diabetes. Pruebas adicionales confirmaron que tenía cáncer de páncreas. bit.ly/4epvkDF
Daraxonrasib, the first KRAS drug for pancreatic cancer, is now available through an expanded access program, but your physician must apply for you. bit.ly/4uWZ9C5
When Dr. Brian Wolpin read the final results from the phase III daraxonrasib trial, everyone was on their feet at the 2026 ASCO meeting. bit.ly/3RZWRnH
Dr. Despina Siolas @DrDespina123 is focusing her research on new treatments for pancreatic cancer, particularly ones that go after KRAS mutations. bit.ly/4xgaaQR
Pancreatic cancer will look very different in 5 years
✅ KRAS is no longer "undruggable"
✅ Neoantigen vaccines may stop recurrence
✅ AI can identify 'occult' tumors from routine scans
We tackle these stories in our new episode!
#onlyoncologistsinthebuilding
A potential breakthrough in pancreatic cancer treatment is giving physicians new hope.
“Having treated pancreatic cancer for 16 years, I actually started crying,” said Rachna Shroff, MD, MS. “It’s unprecedented.”
@rachnatshroff
Read more @pbsnewshour: to.pbs.org/4e4byxn