Excited to share our review on metabolic adaptations in brain metastasis in @NatureRevCancer!! 👉rdcu.be/exHzY A pleasure to co-write with Pravat @CMTLab_IISERBPR and appreciate the support Daniela @DaniS2911 @utswcancer @UTSWCancerBio @UTSW_Pathology @UTSWMedCenter

Tumor Evolutions, Chromosomal Instability, and Metastatic Tissue Tropism: Samra Turajlic, Maxine Sun, Natalie R. Abuelsamen, Eleonora Dondossola, and Srinivas Malladi addressed this topic in a plenary session at #AACRkidney26. @ED_PhD_ @MalladiLab @maxinesun

Excited to host Dr. Mikala Egeblad at the next #KomenBreastCancerForum 11/19- 9am NB-5.124 @UTSWMedCenter @UTSWCancerBio @UTSWScience @UTSW_Pathology @UTSWMolBiol @utswimmuno @megeblad @JohnsHopkins @AriellaHanker @QingZhangLab #InnateImmunity #Metastasis #TMEhost See you all !!

#ThankYouPostdocs #NPAW2025 vimeo.com/1117184279/66c463d…

It was a great experience co-writing with Dr. Srinivas Malladi (@MalladiLab) on this comprehensive review on metabolic adaptations of brain metastasis published in @NatureRevCancer (bit.ly/44KqhtS). Many thanks to @IISER_BERHAMPUR and @ANRFIndia for their support.

Check out this review by @MalladiLab on metabolic adaptations of #brainmetastasis, with a framework for understanding/targeting metabolic vulnerabilities. It's encouraging to see the recent progress, as I lost my grandfather to a brain met, and my dad to a primary brain tumor 👇

#REVIEW 🚨 Parida & Malladi highlight tumour cell metabolic adaptations and crosstalk in the brain & discuss potential strategies to target these adaptations to improve outcomes for patients with brain metastasis. 📖 👇 bit.ly/44RMxC5

Metabolic adaptations of brain metastasis buff.ly/WrODPJg Brain🧠 metastases present a significant clinical challenge due to their high mortality and limited treatment options, driven by complex and dynamic metabolic adaptations that allow tumor cells to survive and grow within the brain’s unique microenvironment. These adaptations differ depending on the tumor's origin, genetic makeup, and ability to tolerate nutrient stress, with proliferative and dormant cells showing distinct metabolic profiles. Cancer cells rewire key metabolic pathways—such as glucose, fatty acid, and amino acid metabolism—not only for their own survival but also to manipulate brain-resident cells to support metastasis. This metabolic heterogeneity reveals the limitations of uniform treatment strategies and highlights the need for tailored therapeutic approaches, which are the focus of emerging research in preventing and managing brain metastases. @CMTLab_IISERBPR @MalladiLab #OncoAlertAF @nataliagandur @acampsmalea @BRicciutiMD @yekeduz_emre @HHorinouchi @FadiHaddad_MD @Abdallah81MD @FernandoOnco @ElisaAgostinett @to_be_elizabeth @bavilima @realbowtiedoc @Erman_Akkus @Lucarecco @GaiaGriguolo @JankovicK @MarioBalsaMD @DrMirallas @GIMedOnc @OscarTahuahua @matteolambe @double_whammied @stage4kelly @coffeemommy @itsnot_pink @maryam_lustberg @kevinpunie @nicolobattisti @raalbany @stolaney1 @LoiSher @jamecancerdoc @JavierCortesMD @JaniceTNBCmets

Up next Basic/Translational session at UT Christopher G Wood Austin meeting chaired by @PavlosMsaouel with Dr Lei Zheng @UTHSAResearch lessons from ICI in PDAC, @drdonnahansel mTORC2 in UC @MalladiLab ccRCC met latency /recurrence and @SGoswamiMDPhD epigenetics and IO interplay

Dr. Srinivas Malladi @MalladiLab with great discussion on cell competition that may shape metastatic latency and relapse in RCC @KCPUTSW @JBrugarolas @TiansterZhang @utswcancer @KidneyCancer #IKCSNA24

Great presentation by @MalladiLab @KCPUTSW at #KCRS24

The latest and greatest in #kidneycancer. Join us for FREE online #KCRS24. Thank you @KidneyCAN, the volunteers, outstanding faculty and colleagues for all the hard work.

Candidates interested in pursuing #postdoc training @UTSWScience can join us for 'Pathway 2 Postdoc (P2P)' in October to learn more about our program.

An amazing scientific and educational programs this year at EANO (Glasgow). Check it out! Time to register!

Thank you @BravoCorderoLab !! Was great to meet everyone @BadoIgor @Elvin_Wag @Goutam_Chak @TischCancer @AmaiaLujambio @DDSoLab @andrewlji !! Also great Tapas and Paella for dinner !! Cheers !!

Excited to meet everyone tomorrow!! Thank you for the invitation @BravoCorderoLab!! @utswcancer @UTSW_Pathology