Research fellow at the Dana-Farber Cancer Institute and Harvard Medical School. Computational immunology / Spatial transcriptomics
Joined January 2019
- Tweets 180
- Following 282
- Followers 341
- Likes 705
19 Photos and videos
Pinned Tweet
Feb 11
Excited to share our latest study published in @CellCellPress !!
We uncovered that a single oncolytic virus injection can ignite deep, persistent T cell immunity in glioblastoma, lasting months to years.
sciencedirect.com/science/ar…
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Maxime Meylan retweeted
Mar 23
Excited to share- Building on our work defining TRMacs heterogeneity, we show that distinct chemokine IM subsets and recruited TAM niches shape pro- and anti-tumor immunity within to the TME, while Ag moDCs trafficking to LNs dampen DC-based neoAg vac
nature.com/articles/s41590-0…
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Maxime Meylan retweeted
PICI researcher Kai Wucherpfennig, MD, PhD, of @DanaFarber’s research shows a single injection of an oncolytic virus can trigger lasting T cell immunity against glioblastoma. Read more about the study and its impact here: bit.ly/4suBcRe
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Maxime Meylan retweeted
Feb 12
Now online! Persistent T cell activation and cytotoxicity against glioblastoma following single oncolytic virus treatment in a clinical trial dlvr.it/TQvdv2
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Maxime Meylan retweeted
Feb 11
A new study led by @DanaFarber’s Dr. Kai Wucherpfennig and colleagues shows that an injection of a genetically modified virus that selectively infects and destroys cancer cells can recruit immune cells to penetrate and persist deep within brain tumors.
➡️ bit.ly/4atTuee
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Maxime Meylan retweeted
24 Sep 2025
🚨Paper alert 🚨
Check out our latest paper: We identified SPP1 as a key regulator of mesenchymal cell fate. Together with GREM1, SPP1 regulates reciprocal epithelial and mesenchymal PDAC cell fate.
📚Read more about this @Nature paper below ⬇️:
nature.com/articles/s41586-0…
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Maxime Meylan retweeted
9 Jan 2025
1/ 🧵Excited to share our latest study published in @NatureCancer co-led with amazing co-first authors and friends @TJammihal and @ChrisLabaki under the exceptional mentorship of @DrChoueiri @BraunMDPhD @ShuklaSachet
nature.com/articles/s43018-0…
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30 Oct 2024
💯
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Maxime Meylan retweeted
26 Oct 2024
In a new Science study, researchers report that cancer cells can be reprogrammed in vivo into dendritic cells that can activate T cells and promote antitumor immunity.
Learn more ⬇️
📄: bit.ly/4eS9Y0L
#SciencePerspective: bit.ly/4eUiHPW
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Maxime Meylan retweeted
26 Oct 2024
I haven’t posted much since Twitter is X, but I have a good reason today☺️ if you like #cancerstemcells #stemcells and #immunotherapy, this is for you! With partner in crime Phoenix Miao😎 nature.com/articles/s41568-0…
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16 Oct 2024
Exiting new method, looking forward to trying it!
15 Oct 2024
Very excited to present STAMP: An Interpretable spatially aware dimension reduction of spatial transcriptomics nature.com/articles/s41592-0…
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Maxime Meylan retweeted
16 Oct 2024
Check out our new article in @NatureRevCancer where we take a deep dive into early myeloma and discuss the potential of T cell-redirecting therapies!
nature.com/articles/s41568-0…
@IrenemGhobrial @JbAlberge @LucaBertamini and Rosa Toenges @DanaFarberNews #mmsm
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Maxime Meylan retweeted
10 Oct 2024
Happy publication day for us! Labor of love with @CoffmanLab #TLS #ovariancancer @UPMCHillmanCC @PittTweet
The activity of tertiary lymphoid structures in high grade serous ovar... sciencedirect.com/science/ar…
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Maxime Meylan retweeted
20 Sep 2024
CAST enables physical alignment of spatial omics data across replicates, techs, modalities at single-cell resolution. Such accurate alignment enables spatial atlas searching, unbiased DEG identification, and reconstruction of spatial multi-omics. DM for questions and collabs!
19 Sep 2024
With the growing availability of spatial omics data from different techniques, CAST offers a computational tool for reconstructing single-cell multi-omic profiles and downstream analysis in a spatially resolved manner. @WangXiaoLab
nature.com/articles/s41592-0…
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Maxime Meylan retweeted
16 Sep 2024
Happy to share Novae, our new foundation model for spatial transcriptomics data 💫
Load a pre-trained model and start using Novae in two lines of code!
biorxiv.org/content/10.1101/…
github.com/MICS-Lab/novae
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Maxime Meylan retweeted
10 Aug 2024
Benchmarking clustering, alignment, and integration methods for spatial transcriptomic. #SpatialTranscriptomics #MethodsBenchmarking @GenomeBiology
genomebiology.biomedcentral.…
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Maxime Meylan retweeted
14 Jun 2024
How is CRI-Mike Goguen Immuno-Informatics Postdoctoral Fellow @MaximeMeylan @DanaFarber discovering a world #Immune2Cancer? Fuel the future of cancer research, and double your impact today! All donations will be matched up to $300,000 only until June 30: bit.ly/3UGAKjy
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Maxime Meylan retweeted
9 Jun 2024
Bit of a change of topic, but let's talk about cancer.
What causes cancer? We learned in high school that it's mutations in oncogenes- "cancer is not one disease, it's many different diseases, each driven by a different oncogenic mutation." (1/)
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