new out in Nature nature.com/articles/s41586-0…

Crazy—we took a quick look at our platform data to see if it supported how it "feels" out there. 2024 is on trend for the lowest programs against "new drug targets" in ~30 years. This kind of risk aversion very bad for future patients, especially with so much strong new omics-driven evidence and broadly rising drugability.

How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/S0092…

Epithelial extrusions in asthma

A deeply moving memoir of an enchanting person I first met a few days after she was born. Thank you ⁦@davidfrum⁩ theatlantic.com/magazine/arc…

Inspired by a golden hour by the Pacific convergentlines.blogspot.com…

Interesting foray into the vast open field of macrophage mechanobiology

'Living through seasons' - in dialogue with the changing landscapes of life tinyurl.com/43z7nyz8

A few words on the different aspects of creative work convergentlines.blogspot.com…

We found that chronic stress increases metastasis in mice. The neutrophils are at the helm (again!). Link to our report in @Cancer_Cell: authors.elsevier.com/a/1ieO0…

Our paper on the cover of @ScienceTM! What's more, it features my photograph of a cobra from our beautiful @iiscbangalore This is a collab with Jardine lab at @scrippsresearch, @CSRIatLSTM, et al. Takes us 1 step closer to Universal antivenom for treating snakebite @LabVenomics

Huge congrats to Cathy Wu for the Sjöberg Prize and wonderful coverage today on CNN. Very well-deserved. Cathy is a truly groundbreaking scientist and also exceptional human being. Bringing more immunology to more cancer patients. cnn.com/2024/02/20/health/ca…

T cell lymphoma mutations power adoptive T cell therapies! Excited to see this published! A true collaboration with friend and colleague @koleroybal and our students @jay__daniels and #julie_garcia. nature.com/articles/s41586-0…

I’ll be speaking about my work on tumor associated macrophages this Thu Feb 8 👇🏽

The #MyeloidNetwork is on Twitter / X! Just in time to announce February seminar speaker @MellmanIra! Join us! Details 👇🏼👇🏼 @JudithVarner2 @Zarif_Lab @GabrilovichLab @coussens_lisa @Johanna_A_Joyce

OBS #Cancer #Immunology Seminar 📆 Thu, February 8, 11 am ET/17h CET 🎙️ @MustaphaSibai @CarrerasIJC 🎙️ @RayArja @UCSF Moderator @asalboix @FCI_health ✍️ us02web.zoom.us/meeting/regi… #openscience

Hope you can join @MaxKrummel and I at the keystone meeting we have organized on Myeloid Targeting Strategies for Cancer Treatment, this May in Killarney! keysym.us/KSMyeloidTargets24 #KSMyeloidTargets24

Our latest story is out in @CellPressImmunity today!! We show that Stat5 opposes Tox and rewires exhausted CD8s towards more durably protective effector-like states. Shout out to my co-authors, @parkerici and @EJohnWherry Key take-home messages in the 🧵⬇️ cell.com/immunity/ppt/S1074-…

🌟Excited to share our latest work on how functionally distinct skin TRM utilise different pathways to establish residency, published today in @ScienceMagazine! A true labour of love by BFF @simpak and @susanna_c_! 👩‍🔬 @TheDohertyInst @UniMelb @UniMelbMDHS science.org/doi/10.1126/scie…

1/n: We are excited to share that our paper on Chroma, a general purpose diffusion model for proteins, is out today in @Nature! nature.com/articles/s41586-0… A couple of my favorite highlights in the 🧵below 👇