Group Leader @BabrahamInst. He/him. All things #ubiquitin #proteostasis #proteomics #ageing #senescence. Spend too much on food & wine. Opinions mine, all mine!
Joined March 2012
- Tweets 3,216
- Following 1,683
- Followers 1,661
- Likes 22,168
298 Photos and videos
Rahul Samant retweeted
Finally out in @Cellcellpress!
Proteins with long intrinsically disordered regions (IDRs) are prone to misfolding during protein synthesis.
This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones.
cell.com/cell/fulltext/S0092…
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Rahul Samant retweeted
Our latest study out in @MolecularCell explores how and why MHC class I is aberrantly targeted for degradation via the autophagy-lysosome pathway in pancreatic cancer. Congrats to postdoc extraordinaire @marineberquez for leading this study! @UCSFAnatomy @UCSFCancer
May 29
Online Now: A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer dlvr.it/TSn7r3
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Rahul Samant retweeted
May 8
A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia: academic.oup.com/brain/artic…
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Rahul Samant retweeted
May 8
Phosphorylation tunes p62 condensates to drive autophagic degradation of ubiquitinated proteins: link.springer.com/article/10…..
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🚨 Registration is now open!🚨
Join us at the Young ICSA Symposium – Salamanca Edition 🇪🇸
📅 15–16 Sept 2026
📍 CIC Salamanca
Early-career researchers in cellular senescence: connect, present your work & build collaborations.
🔗 yicsasalamanca.wordpress.com…
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Rahul Samant retweeted
May 2
The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency #mitochondria
nature.com/articles/s41467-0…
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Rahul Samant retweeted
🟢Registration is now open for Senescel 2026 (Sept 16-18, Salamanca, Spain).
Enjoy a fantastic lineup of international speakers on aging and cellular senescence at one of the liveliest university towns in Spain.
senescel2026.org/registratio…
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Rahul Samant retweeted
📋If you have an advanced project ready for presentation at SENESCEL or @YicsaC, consider submitting the manuscript to @AgingJrnl for this special collection on Cellular Senescence.
Apr 8
📢 #CallforPapers:
Aging-US invites #submissions on cellular #senescence - its mechanisms, functions & clinical applications - in memory of Dr. Judith Campisi.
📅 Deadline: May 31, 2026
🔗 Submission Details:
aging-us.com/judith-campisi-…
#AgingResearch #OA #Aging #Publishing
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Thrilled to share our new paper: SLC33A1 is the long-sought ER GSSG exporter, maintaining redox homeostasis in the ER. Huge congratulations to my co-first author @shanshanliu1218 and my PIs @KivancBirsoy and @HiteLabMSKCC for leading this work. nature.com/articles/s41556-0… 🧵 1/9
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Rahul Samant retweeted
Years in the making: a detailed aging gene signature in mice and rats. >30 tissues, high Ns, multi-time points throughout the lifespan. >5000 samples in total. The data is accessible, so you check to see if your favorite gene is age-regulated.
science.org/doi/10.1126/scia…
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📢 Update: Our upcoming yICSA Webinar with Amina Abdul-Aziz has been rescheduled to May 22nd at 16:00 CEST. We look forward to hearing about her journey from leukemia research to senescence biology!
us06web.zoom.us/meeting/regi…
There is still time to register for our next yICSA seminar series! Link below ⬇️
us06web.zoom.us/meeting/regi…
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Apr 15
Don't miss David Vilchez's #Proteostasis Consortium Seminar today (4pm UK time). Super story about why being a bit cold might be good for you (if you're a worm). proteostasisconsortium.com/s… #aging #ageing #longevity
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Rahul Samant retweeted
Apr 10
mtHsp70 chaperone converts mitochondrial proteostasis stress into impaired protein import | PNAS pnas.org/doi/10.1073/pnas.25…
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Rahul Samant retweeted
Apr 7
Now online! Senescence in cancer: Hallmarks, paradoxes, and therapeutic promise dlvr.it/TRwHzm
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Rahul Samant retweeted
Protein synthesis is not equally accurate across organs.
Excited to share our new preprint:
biorxiv.org/content/10.64898…
We developed a new mouse model to quantitatively monitor translation errors and uncovered the spatiotemporal dynamics of the “quality” of protein synthesis.
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Rahul Samant retweeted
⏳There is less than ONE WEEK to go until our #UbiquitinFunction registration deadline (Tuesday 07 April)
🙋♀️Don’t miss your opportunity to register and join us in sunny Portugal. Connect with industry experts, discover fresh insights, and network with like-minded professionals.
🎟️ Register now before it’s too late!
🔗bit.ly/4bnlaSC
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Rahul Samant retweeted
Mar 26
📹OUT NOW! We present a protocol to enable the capture & identification of disease-specific protein-protein interactions from native cells & tissues using chemical probes & mass spectrometry app.jove.com/v/69197/ #Proteomics #interactome #omics #dfPPI #SciComm @JoVEJournal
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Rahul Samant retweeted
🚨 #BSRA2026 is LIVE! Registration now open for our 75th Annual Meeting
📍 Oxford (Keble College)
Great science, great people, and some special 75th year surprises 👀
Tag someone who should be there!
🔗 meetinghand.com/e/75th-asm-o…
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Mar 27
Unfortunately, photos from the after-hours mini-golf celebration are being vetted and may not be suitable for publication without substantial revisions.
Mar 27
Clocking in at just under 4 hours, the examiners commended Devinda for her thoughtful approach during the viva, and ability to stand up (sometimes literally...) for her convictions.
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