VastDB is a repository of quantitative profiles of alternative splicing events and GE data across different tissues and species. Developed at @CRGenomica
Joined July 2017
- Tweets 173
- Following 426
- Followers 306
- Likes 138
17 Photos and videos
We have released a new batch of functional annotations (v11): 600 entries from previous publications investigating the function of AS events. This makes a total of 3637 entries directly from publications, 397 from CRISPR screens and 1511 from experimentally validated ELMs.
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Cotyledon opening during seedling deetiolation is determined by ABA-mediated splicing regulation
embopress.org/doi/full/10.10…
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VastDB retweeted
24 Jan 2025
This sounds like a dream!! Barcelona and Berlin with amazing scientists and great people. Having worked with both groups I would highly highly (yes twice :) recommend it.
21 Jan 2025
The job call is officially open. If you're interested, please apply through this link ASAP! 😃
mdc-berlin.de/career/jobs/po…
Please RT! 🙏
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30 Dec 2024
🐟Our new paper "Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish" is out in @eLife🐟
A nearly 10-year tour-de-force by Laura Lopez-Blanch and many others in the lab @CRGenomica & @UPFbiomed
elifesciences.org/reviewed-p…
Thread👇
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23 Dec 2024
🚨🚨🚨
If you're a bioinformatician who loves:
🧬 #SingleCell #LongReadSequencing & #AlternativeSplicing
🚀 Collaborating and travelling
Apply to work with us at the spectacular @BIMSB_MDC in Berlin @UPFbiomed-@CRGenomica in Barcelona. Qs:transdevolab.com
Please RT!🙏
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23 Dec 2024
📢 We're hiring!
We are looking for two excellent early career candidates to join #MELISupf as Junior Group Leaders in Computational Biology, and in Quantitative Biology
More information and application links: upf.edu/web/biomed/job-offer…
Deadline: 28 Jan 2025
#JobOffer
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5 Dec 2024
Finally out nature.com/articles/s41586-0… the study (led by @xsalvatella1 & @RMendezLab) with the biophysical explanation for the profound effect of the microexon of CPEB4 as cause of autism, that we previously reported back in 2018
@ParrasAlbert @GeschwindLab @mirimiam @hervas_millan
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5 Dec 2024
Who would have thought that an actual sequence of a #microexon (GCAAGGACATATGGGCGAAGGAGA from CPEB4) would be in the headline of an article in @elpais_espana! Congrats to the Mendez, @xsalvatella1 and @JJLucasLab labs for this amazing work!
english.elpais.com/science-t…
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10 Dec 2024
We’re recruiting a PhD student to use comparative omics to investigate why some viruses can efficiently infect both human and mosquito cells, but lead to different infection outcomes. Fully funded position by @EvoMG_Bcn at UPF-CRG with the @ViroUPF lab.
crg.eu/en/content/training-p…
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11 Dec 2024
Circular RNAs trigger nonsense-mediated mRNA decay: cell.com/molecular-cell/full…
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9 Dec 2024
Come to the dark side! Join the #darkproteome team to work on plant functional annotation within our OSCARS
@HorizonEU
project FAIRFUN4Biodiversity. Great project, great advisor, great city and great team! 👇👇
@CsicLifehub
9 Dec 2024
Are you interested in genome annotations? Do you want to work in Valencia, Spain. We have an open position at @IBMCP. Please contact me if you are interested or forward to who may you think that could be interested.
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1 Dec 2024
Thrilled to share this new work resulting from a great collaboration of my lab with the labs of @imaesomar and @veronica_hinman, started with the dear José Luis Gómez-Skarmeta many years ago. Take a look!
biorxiv.org/content/10.1101/…
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24 Nov 2024
Big🧬news this week: we have launched the first Joint Program on Evolutionary Medical Genomics. Spearheaded by @mirimiam, Barcelona researchers will study and exploit the vast genomic diversity of life on Earth to enhance precision medicine.
english.elpais.com/science-t…
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2 Nov 2024
Great collaboration with @lrdesviat and @AndresenBrage to find ways to modulate inclusion of a microexon (CPEB4 exon 4) involved in autism!
@sarapico7 @mirimiam @GeschwindLab @ParrasAlbert @RMendezLab @SENC_ @CBM_CSIC_UAM @CIBER_ISCIII
30 Oct 2024
Interested in neuronal #microexons? #splicing? #antisense? #autism? Check out our new preprint👇👇
@CBM_CSIC_UAM @JJLucasLab @AndresenBrage
@UAM_Madrid
biorxiv.org/content/10.1101/…
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31 Oct 2024
🎉Excited to announce that our paper on the blueprint of the human spliceosome is now out in @ScienceMagazine ! A decade of work with Juan Valcárcel and the incredible team at @CRGenomica to uncover the intricate roles of this essential RNA machinery.science.org/doi/10.1126/scie…
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30 Jul 2024
Out now: Using highly sensitive luminescence splicing reporters, we screened ~95,000 small-molecule compounds for modulators of neuronal microexons, a class of highly conserved alternative splicing misregulated in #autism & #NeuroendocrineCancer. 1/4 go.nature.com/3Wh6kp2
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10 Jul 2024
Published today! We found that cancer cells adapting to drug treatments don't simply switch from a sensitive to resistant state; instead there's a ‘resistance continuum’ of resistant phenotypes with epigenetically reprogrammed states. 🧵⬇️
nature.com/articles/s41586-0… @Gustavo_SFranca
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17 Jun 2024
🚨 We're excited to announce our Inaugural Symposium on Evolutionary Medical Genomics (EvoMG) at @the_prbb in Barcelona, November 20-22 2024.
👇Our great speakers and topics!
Further info: evomedgenomics.com/events/in…
@CRGenomica @UPFbiomed @IBE_Barcelona
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17 Jun 2024
Very excited to announce the inaugural symposium of our @EvoMG_Bcn Joint Program on Evolutionary Medical Genomics!
Join us in Barcelona on the 20th-22nd of November (no registration free).
Great speakers and cool and diverse topics!
@CRGenomica @UPFbiomed @IBE_Barcelona
17 Jun 2024
🚨 We're excited to announce our Inaugural Symposium on Evolutionary Medical Genomics (EvoMG) at @the_prbb in Barcelona, November 20-22 2024.
👇Our great speakers and topics!
Further info: evomedgenomics.com/events/in…
@CRGenomica @UPFbiomed @IBE_Barcelona
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15 Apr 2024
The peer-reviewed version of our study on the evolution of tissue-specific expression across vertebrates and insects is finally published in @NatureEcoEvo ! @FedeMantica @CRGenomica @UPFbiomed
nature.com/articles/s41559-0…
16 Nov 2022
🚨Exciting pre-print from the lab!👉"Pervasive evolution of tissue-specificity of ancestral genes differentially shaped vertebrates and insects". Deep comparative #transcriptomics across #bilateria by @FedeMantica et al @CRGenomica. 👀biorxiv.org/content/10.1101/…. Summary👇
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22 Mar 2024
Job alert!
We offer two positions (Team leader & Bioinformatics developer) to work on the Biodiversity Cell Atlas database: unified pipelines, data curation, and cross-species integration. With @irenepapatheodo @RodericGuigo @ExpressionAtlas @emblebi
🗓️Apr-10
🔗Details below
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