154 Photos and videos
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🆕️Brilliant findings @PeterLyLab
Horizontal human DNA transfer via nanotube connections
Transferred DNA fragments confer heritable phenotypic traits to recipient cells
#cancer
DOI: 10.1016/j.cell.2026.04.041
@CellCellPress
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Admirable work from Brazil🔥
Water & #p53: Functional flexibility at the expense of stability
[One of my favourite topics in #oncobiochemistry]
Frustration analysis reveals evolutionary conservation
#cancer #chemistry #TP53 #mutation
doi.org/10.1038/s42004-026-0…
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Anu R I retweeted
May 18
Precancerous niches as gatekeepers of tumor initiation dlvr.it/TSbv10
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Anu R I retweeted
May 14
This is a global issue for both Cisplatin and carboplatin .. @ChandrakanthMv needs to be highlighted … affecting so many pts @AyushmanNHA @CancerGridIndia @cspramesh @ASCO @DrSanjayPopat @myESMO … not an expensive drug so industry not bothered. @PMOIndia @JPNadda @ICMRDELHI @jrgralow @drkiwicj
May 14
• Platinum chemotherapy shortage in India is becoming a major oncology challenge
• Cisplatin & carboplatin are backbone drugs across many cancers
• The issue is not just “drug availability” → raw material crisis → pricing pressure → manufacturing economics → supply-chain disruption
• Real-world impact: → treatment delays → dose modifications → regimen changes → inventory pressure
• Quick visual summary of: ✓ What is happening
✓ Why it is happening
✓ Clinical implications
✓ Possible solutions
Would like to hear how different centres are managing this situation.
#Oncology #CancerCare #DrugShortage #Cisplatin #Carboplatin #Chemotherapy #OncTwitter #MedTwitter #MVOnco
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⛔️First case reported:
13-month-old boy treated with #genetherapy for #HurlerSyndrome develops tumor at age 5 post adeno-associated viral genome integration resulting in AAV-PLAG1 transcript in brain cells.
#biochemistry #cancer #MPS1 @NEJM
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Anu R I retweeted
#TumorBoardTuesday
⌛️1y ago we learned of a major📈in the cure for early stage gastric cancer
📢Join us Tuesday, 05-12-26 at 8PM ET as @SunnieSKim & @aprilchoi_md 🗣️updates to the MATTERHORN trial & Tx for early stage #gastriccancer
RT and bring others into the discussion‼️
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Interesting!
nature.com/articles/d41586-0…
Cohort: 12.5m researchers
Experienced researchers are less likely to produce ‘disruptive’/'novel' science
Nostalgia effect: As careers progress, scientists are more likely to cite older papers than newer ones.
#research
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Anu R I retweeted
First PROTAC gains FDA approval, bolstering targeted protein degradation and induced proximity ambitions
nature.com/articles/d41573-0…
Arvinas and Pfizer’s oestrogen receptor degrader vepdegestrant has secured approval for a subset of patients with advanced or metastatic breast cancer
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Wonderful work @UMichMedSchool
✅️Variant function assessment #VUS #cancer #MAVE
Saturation mutagenesis DNA repair reporter assay to show
Functional enzyme activity of MUTYH 》》 Base Excision Repair🔥
DOI: 10.1016/j.ajhg.2025.07.005 @CellCellPress
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Biology's dwarf planets!
TransCODE Consortium finds #darkprotein
microproteins & peptideins
Translational products with unknown function from ncORFs
nature.com/articles/s41586-0…
#cancer #proteomics
@AfshinBeheshti @joseph_borg_ @mason_lab @RyanTScott
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#AACR26 Closing Plenary: excellent summary by @UTMDAnderson
#ClinicalTrials to look forward to!
@AACR
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#AACR26 Closing Plenary
@AACR @YaleCancer
TOP CONCEPTS
Proximity-inducing: Degraders
Docked Deliveries: ADCs
Cellular Therapy advancements
Personalized vaccines
MRD
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#AACR26
Immensely happy to showcase our work!!! 🎗 👩🚀 @AACR
@mason_lab @AfshinBeheshti @RyanTScott @joseph_borg_ @KurtSpeeten @ josefborg @KJangkeun @ tricialarose
@YJanjigianMD
@NASAGeneLab @PittTweet @WeillCornell @UMmalta @Spaceomix @uhasselt
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#AACR26 Day 5
Plenary Session: #MutationalSignatures
Its always a pleasure to listen to Dr Ludmil Alexandrov!
■Investigating causality
■Early detection
■Fingerprint of cancer
@AACR @UCSDHealth @SerenaNikZainal
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This was for me the best part of #AACR26!💛
Meeting Dr @YJanjigianMD again and talking about work & much more!
Thank you for your unwavering support over the years💫
@MSKCancerCenter @AACR @ESMO
@Spaceomix
#oncology #cancerresearch #Immunotherapy
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#AACR26
🔥Synthetic Lethality and DNA Damage Repair
Good sessions from @DanaFarber @UofCalifornia @UMassChan
This will always be a challenging path as we intend to target evolutionarily conserved cellular ecosystems.
Also follow @kaelin_lab for SL!
@AACR
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Happy to see @JiwoonPark_ present her phenomenal work on organotropism and metastatic site prediction in CRC at #AACR26
Great work @mason_lab @SingularGenomic
@AACR
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