A New Year, a new paper out on Jan 1 in @ScienceMagazine ! Congratulations to @SiddhantUJain and all our co-authors and collaborators! This study answers a longstanding question in our field regarding recruitment of chromatin regulatory machinery and provides a powerful new framework for development of precision medicines in #cancer and beyond! @kadochlab @alex2110x @hhmi_science @DanaFarberNews @DanaFarber science.org/doi/10.1126/scie… #generegulation #chromatin #cancer #therapeutics #basicscience #BAFcomplex #mSWISNF #chromatinremodeling

Excited to see our collaborative work with @Oser_Lab @DanaFarber @DanaFarberNews on #SCLC #lungcancer out in @Cancer_Cell, identifying chemically targetable #BAFcomplex chromatin regulatory dependencies and providing foundation for new clinical studies for this aggressive cancer.

Kudos to Megan Mcnerney, MD PhD and her team on publishing an excellent research article in @CellReports demonstrating #CUX1 regulation of hematopoietic stem cells via #BAFComplex. @UCCancerCenter @UCPathology @UChicagoCCB ow.ly/L37W50S0lWX

Exciting new results from our @kadochlab with the Politi lab at Yale highlighting the utility of mSWI/SNF #BAFcomplex ATPase inhibitors in reversing kinase inhibitor #drugresistance in #EGFR-mutant #lung #cancers. Congrats to the team on this timely and impactful study!

Exciting new work highlighting the utility of #mSWISNF #BAFcomplex ATPase inhibitors in reversing kinase inhibitor resistance in EGFR-mutant lung cancers @Cancer_Cell ! A great collaboration with @politikaterina lab at @YaleCancer ! Congrats to @fdemiguelsdp , @claudiagentile_ !

Congratulations to @FreddyMValencia and @akshaysci on their newest study, just published in @NatureGenet ! Beautiful analysis highlighting that #SWISNF /#BAFcomplex genes are the most frequently perturbed gene classes in #neurodevelopmental disorders. nature.com/articles/s41588-0…

Another great story from Kadoch lab and @iannisaifantis1 lab @CKadoch “ targeting #BAFcomplex for T cell maintenance/exhaustion” another step towards improving anti tumor therapies 👏🏻👏🏻 read for today

Congrats to @ajinkyapatil00 from my @kadochlab @DanaFarber @harvardmed @HHMINEWS and @JinWei0911 from the @WilenLab @YaleMed on this exciting new study! #chromatin #viruses #sarscov2 #COVID19 #BAFcomplex #inhibition

Big congratulations to @ajinkyapatil00 from our @kadochlab and @JinWei0911 from the @WilenLab @YaleSOM on their terrific new study out today in @NatureGenet -- a fantastic collaboration! @CKadoch @DanaFarberNews @harvardmed #sarscov2 #virus #chromatin #BAFcomplex

Up Next @foghorntx talking #ChromatinRemodelers #BAFcomplex Thanks for being part of #CEI2023Symp @CKadoch

🚨#phdpositions available with @luck_katja 1️⃣ Role of #BAFcomplex in #GenomeStability ➡imb.de/students-postdocs/int… 2️⃣Protein degradation in #NuclearCondensates ➡imb.de/students-postdocs/int… Apply by 19 Nov imb.de/PhD #proteomics #Bioinformatics #Biochemistry #Biophysics

Congratulations to @kadochlab members @proodolph, Clayton Collings, and our many collaborators on this exciting new study focused on the mechanism of an aggressive #meningioma subtype! #cancer #BAFcomplex #chromatin #ncBAF #BRD9

What is the prenatal phenotype of Coffin-Siris syndrome? #ARID1A #BAFComplex #Fetal #SMARCA4 #SMARCB1 gimjournal.org/article/S1098…

Just released the results of an incredibly fruitful collaboration with experts around the world: "BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma" #rhabdomyosarcoma #BAFComplex #PAX3FOXO1 nature.com/articles/s41467-0…

#cancer #CancerResearch #chromatin #transcription #SWISNF #BAFcomplex #humandisease

In every 5th cancer there's a mutation found in 1 of the #BAFcomplex genes. In their new @NatureGenet paper CeMM PI Stefan Kubicek’s lab revealed how quickly changes in this complex' genes influence the accessibility of DNA🧬 & the information stored in it cemm.at/news/n/news/inhibiti…

There’s a new BAF complex in town. Say hello to non-canonical BAF. Thanks for the discovery @CKadoch! #BAFcomplex #chromatinremodeling #ADCR hubs.ly/H0kj3sy0

I had the great honour to do the visualisation for the Chemical #Epigenetics Lab @CeMM_News, their breakthrough research has been published @NatureGenet, @oeaw covers their findings concerning #Cancer and #BAFComplex-mutations in more detail (german) oeaw.ac.at/detail/news/krebs…

Watch the @CeMM_News video about the @NatureGenet paper of Sandra Schick & Stefan Kubicek in collaboration with @Boehringer. BAFfling cancer growth strategies: new targets for chromatin remodeling mutations identified. #Epigenetics #BAFComplex #Cancer vimeo.com/354669119/26584ac0…

Brg1 (D1Q7F) Rabbit mAb #ChIPseq #AbValidated #antibody. #ChromatinRegulation #TumorSuppressor #BAFcomplex hubs.ly/H06Vv-_0