Uro-Oncology | Urothelial Carcinoma · Robotic Surgery | Kidney Transplant Surgeon | AI in Uro-Oncology | EAU-YAU | Clinical Trials | Hospital Ramón y Cajal

Joined September 2009
79 Photos and videos
Jose Daniel Subiela retweeted
🥇Happy to have received the prize for the most cited article for the Resident's Section in 2025 in @actasurologicas @InfoAeu #AEU26, brilliantly written by Silvia Juste 🔗Read it here: t.ly/8VmM- @GUOaeu @RodriguezFaba @cgdelcanizo @JGomezRivas @EnguitaCarmen @albertobudiaalb @CoralManso @Urologia12 @ResidentesAEU @H12Octubre @CAU_URO @ResidentesCAU
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Jose Daniel Subiela retweeted
🚀 Delighted to be attending the Inaugural Ceremony of the 89th National Congress of Urology 🇪🇸 A great opportunity to learn, share experiences, and strengthen multidisciplinary collaboration in the care of our patients. 🤝🔬 Looking forward to an inspiring meeting. @InfoAeu
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Jose Daniel Subiela retweeted
Our News systematic review @FPuigvert highlights that pathological response after neoadjuvant therapy may provide valuable prognostic information in metastatic RCC, often beyond what radiological assessment alone can capture. Read here: eu-central-1.protection.soph…
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Jose Daniel Subiela retweeted
👏👏👏 Great job my friend!! 👉 Always working together in a multidisciplinary team!! This the right way to go!! long road to get there! 👉 : the idea➡️ proposal➡️ funding➡️ recruitment➡️analysis / publication @ASCO @UroTarget @OncoAlert @H12Octubre
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Jose Daniel Subiela retweeted
Replying to @UroDocAsh
Fully agree. @josedsh @FVillacampaCUN and I ran those numbers NNT and NNH summarize it pretty well For Sasanlimab the NNT is 14, while the NNH is 4 For Durvalumab the NNT is 23 and the NNH is 6 Statistically more likely to harm (grade 3 or higher) than benefit unelected pts
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Jose Daniel Subiela retweeted
🚨A lot of new options for #BCGunresponsive NMIBC, but no direct comparisons 🤼We've tried to do some work on this, along with my friend @siadaneshmand and others 📖You can read it here @JUrology @AmerUrological @JUOpenPlus: t.ly/UxDFA 👀And much more to come!!!
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Jose Daniel Subiela retweeted
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🧵 Out now in European Urology — our editorial on dual-biomarker monitoring (ctDNA utDNA) for bladder-sparing therapy in MIBC. 4 independent 2026 trials converge: plasma ctDNA & utDNA carry complementary, non-overlapping information. Neither alone is sufficient.
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5 scenarios on the ctDNA × utDNA grid (see figure): 1️⃣ −/− cCR: → preserve 2️⃣ utDNA cCR: → surveil 3️⃣ no-cCR/ctDNA−: still curable locally 4️⃣ ctDNA only: escalate systemic, not cystectomy 5️⃣ / no-cCR: change Tx
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Bottom line: dual-compartment liquid biopsy = rational framework for future bladder-sparing trials. 📖 Free access (50 days): authors.elsevier.com/a/1n6Ng… @Daniel_Urologia @Renate_Pichler @BenjaminPradere #PietroScilipoti

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1/ 🚨 New review: “Perioperative Management of UTUC: Current Evidence & Future Directions” Most of what we do in UTUC is still extrapolated from bladder cancer. We tried to map where we stand — and where the field is heading. 🔗 DOI: 10.1159/000551611 🧵⬇️
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2/ Where we are: ✅ NAC → feasible, active; pathological response = surrogate of survival ✅ POUT → durable DFS benefit emerging OS signal ❌ Neoadjuvant IO mono (PURE-02) → limited ⚠️ Chemo-IO (iNDUCT) → feasible, didn’t meet 1º endpoints ❌ Adjuvant IO → no clear benefit
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3/ Where we’re going: 🔬 ctDNA & utDNA → risk stratification MRD 🧠 Predictive models → reduce overtreatment 📊 Ongoing trials: URANUS, iNDUCT-2, NCT04628767 UTUC-specific prospective trials are no longer optional — they’re urgent.
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1/7 📄 New in Urologic Oncology — a systematic review & meta-analysis of 77 studies and >30,000 patients undergoing radical cystectomy (RC) for non-metastatic bladder cancer. 🔗 kwnsfk27.r.eu-west-1.awstrac…

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6/7 🩺 Clinical implication: candidate selection for adjuvant therapy and surveillance intensity should integrate these factors — beyond pT/pN alone.
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7/7 ⚠️ Heterogeneous RFS definitions remain a key limitation of the field and a priority for standardization. #BladderCancer #UroOnc #RadicalCystectomy #SurvivalAnalysis
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