Saenz Lab is working on the design principles of living membranes. @Saenz_Lab@mstdn.science #lipids #membranes #synbio #RNA #origins #minimallife
Joined March 2018
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116 Photos and videos
Our latest manuscript "Lipid membranes modulate the activity of RNA through sequence-dependent interactions" is... 🎉🎊 published 🎊🎉!! pnas.org/content/119/4/e2119…
@t_czer_jea @James_Saenz @PNASNews @VolkswagenSt @BMBF_Bund @SimonsFdn @BCUBE_TUDresden
Lipids and RNA have something in common: they are essential for life, and most people don’t want to work on them. Now we show that everyone’s least favorite biomolecules actually interact in a useful way. How? biorxiv.org/content/10.1101/… @t_czer_jea @James_Saenz
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14 Jan 2025
Dressed for success 👯
Excited to join the Priority Programme “#Physics of #Parasitism” (#SPP2332) funded by @dfg_public to study #Plasmodium #microtubules together with @StefanDiezLab @PoLDresden & @FrischknechtLab @UniHeidelberg
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13 Jan 2025
Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides buff.ly/4gSQuKc (@BBAjournals)
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13 Jan 2025
The living world is full of fascinating discoveries, from microscopic bacteria to entire ecosystems 🦠🦬🌍 But how do we turn this vast amount of biological data into meaningful concepts?
Join the 2nd edition of 'Theory and concepts in biology' to explore the interplay between theory and biology! #EESTCBio
📥 Submit your abstract by 11 February
💻 s.embl.org/ees25-03-x
🗺️ EMBL Heidelberg and Virtual
📅 6 – 9 May
#biologicalphysics #theoryinbiology #physicalbiology #systembiology #physicsoflife #livingmatter
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8 Jan 2025
I am excited to preprint my postdoc work in the @OlzmannLab! We have discovered the first lipid droplet quality control pathway with broad implications for lipid physiology and diseases associated with LD accumulation and oxidative stress! #lipidtime
shorturl.at/2HqFd
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8 Jan 2025
Choline was first described nearly 175 years ago but our understanding of this essential metabolite is still coming into focus. Excited to share our perspective @NatMetabolism! @samscharenberg @abu_remaileh @KivancBirsoy nature.com/articles/s42255-0…
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Sáenz Lab retweeted
26 Dec 2024
Out now in @MolecularCell our latest work on RNP granules spearheaded by I.R.E.A Trussina. G3BP-driven RNP granules promote inhibitory RNA-RNA interactions resolved by DDX3X to regulate mRNA translatability: Molecular Cell cell.com/molecular-cell/full…
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26 Dec 2024
Refusing an invitation in Britain:
"I'd love to, but I'm afraid I can't, I have to be up early tomorrow. Seriously, it sounds like a lot of fun, but you know how it is. Perhaps we could get together next week..."
Refusing an invitation in Germany:
"No, I don't want to do that"
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25 Dec 2024
Born on Christmas Day in 1876, Adolf Otto Reinhold Windaus was a German chemist who won a @NobelPrize in Chemistry in 1928 for his work on sterols and their relation to vitamins.
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23 Mar 2024
Open postdoc position in Vienna: Development of a simple, yet powerful open-source MINFLUX microscope.
maxperutzlabs.ac.at/news/ope…
Please RT.
2 Nov 2023
We developed an excitation module for 3D multi-color MINFLUX that is simple, stable and cost-effective and will allow for ultra-fast MINFLUX with a high accuracy. biorxiv.org/cgi/content/shor…
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18 Dec 2024
How to measure mechanical properties in just a couple of seconds, from 🐠 to #biofilm? - Optical multi-frequency time harmonic elastograthy! With Liraz Chai @lab_chai led by Jakob Jordan & Ingolf Sack @EBM_research @spp2389 @MPZ_PhysMed @ChariteBerlin onlinelibrary.wiley.com/doi/…
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It was a pleasure hosting you, Alisa! Hopefully by now you are addicted to minimal membranes 🤩
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16 Dec 2024
Join the #SorkinLab at the #TAU! 🔬
Explore how #MembraneProperties affect the formation of #BiomolecularCondensates! Interested in using cutting-edge techniques such as #AFM and #ForceSpectroscopy? Apply for our #PhDposition: comeincell.org/dc14-how-can-…
#ComeInCell #MSCA
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13 Dec 2024
Exciting update on this study - stop by on the blue side to learn more about it...
14 Apr 2024
Buckle up for your Sunday read on the bacterial integron. Recombination sites come in many different shapes and their recombination efficiencies differ by 5 orders of mag?? Great study now on bioRxiv doi.org/10.1101/2024.04.09.5… by Kate in collab with @CelineLoot and @amazeld 1/4
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13 Dec 2024
If you are attending #CellBio2024, check out our lab member's oral and poster presentations. @ASCBiology
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12 Dec 2024
Today I’m joining 30 colleagues in taking an unusual step: calling for a halt to a line of research I was excited about, the long-term effort to build “mirror life”.
We’re sharing our findings in a @ScienceMagazine paper:
science.org/doi/10.1126/scie…
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12 Dec 2024
Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).
12 Dec 2024
Spatially resolved rewiring of mitochondria-lipid droplet interactions in hepatic lipid homeostasis. biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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12 Dec 2024
A new @ScienceMagazine article from 30 leading international scientists including several @JCVenterInst researchers, examines the potential dangers of building ‘mirror life’ — organisms composed entirely of mirror-image biological molecules.
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Sáenz Lab retweeted
12 Dec 2024
At SEVA, we’re all about minimalism, but @LabSaenz just raised the bar 🤯
They engineered a minimal cell membrane with just 2 kinds of lipids! If that’s enough for life, could this open the possibility of further genome reduction? 🧬
Learn more👇
buff.ly/3OLH2Mm
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Sáenz Lab retweeted
11 Dec 2024
Super happy to have Cohen Lab PhD student Ian Windham's paper about #APOE trafficking to #LipidDroplets featured in this exciting collection!!
11 Dec 2024
Our annual collection highlights twelve of the most outstanding papers that showcase the exceptional range and quality of research published by JCB. We are delighted to serve as an independent venue for the awe-inspiring world of cell biology! hubs.la/Q02_fVs30
#CellBio2024
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Sáenz Lab retweeted
10 Dec 2024
PhD alert! I have two ERC-funded PhD positions to uncover the chemical origins of life! Starting date: October 2025. *UK fees only*. Projects described here: lclu.cam.ac.uk/studentship-o…
Email me if interested - deadline (PhD in Biochemistry, Uni of Cambridge): January 7th!
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