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Sovanny Taylor (Sophie) @sovannyruth

@UNC Alumna | @bcmhouston PhD Candidate | Interests: Venom, Biomolecular Condensates, Aging and Neurodegeneration

Joined October 2019
  • Tweets 171
  • Following 213
  • Followers 139
9 Photos and videos
Sovanny Taylor (Sophie) retweeted
IDPseminars@IDPseminars
17 Mar 2025
Announcing the joint IDPSeminars / BPS IDP Subgroup Trainee Symposium Speakers! Join us on Mar 27, 12–2pm CST for 6 exciting talks focused on Intrinsically Disordered Proteins as part of #BiophysicsWeek2025 with the @BiophysicalSoc Sign up now at docs.google.com/forms/d/1L_K…
IDPSeminars/BPS IDP Subgroup symposium. March 27th 2025 at noon central time. Speakers are Ella Mozier, Sara Bologna, Borna Novak, Hamidreza Ghafouri, Ankith Sharma and Ananya Chakravarti!

ALT IDPSeminars/BPS IDP Subgroup symposium. March 27th 2025 at noon central time. Speakers are Ella Mozier, Sara Bologna, Borna Novak, Hamidreza Ghafouri, Ankith Sharma and Ananya Chakravarti!
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Sovanny Taylor (Sophie) retweeted
ShorterLab@ShorterLab
27 Feb 2025
RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry: Cell cell.com/cell/fulltext/S0092…

RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide...

Mammalian cells present RNA-binding proteins on the cell surface that form clustered domains containing glycoRNAs.

cell.com
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Sovanny Taylor (Sophie) retweeted
SpruijtLab@SpruijtLab
29 Dec 2024
Curious how biocondensates localize ions? We found that condensates selectively bind and localize both chaotropic anions and kosmotropic cations. This alters the condensate composition, interface potential and RNA duplex stability inside. By @IrisSmokers biorxiv.org/content/10.1101/…

Selective ion binding and uptake shape the microenvironment of biomolecular condensates

Biomolecular condensates modulate various ion-dependent cellular processes and can regulate subcellular ion distributions by selective uptake of ions. However, the molecular grammar governing...

biorxiv.org
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Sovanny Taylor (Sophie) retweeted
TCH Pediatric Hematology Oncology Fellowship@TCHHemOncFellow
11 Dec 2024
Congrats to Nick DeCleene on defending his thesis under the guidance of Alison Bertuch @TexasChildrens & @BCMHouston, and for donating stem cells @nmdp_org just a week after graduating! Whether in the lab or donating for a good cause, he is an inspiration❤️#StemCellDonor #PhDLife
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Sovanny Taylor (Sophie) retweeted
Molecular Cell@MolecularCell
7 Dec 2024
m6A sites in the coding region trigger translation-dependent mRNA decay dlvr.it/TGfTnN
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Sovanny Taylor (Sophie) retweeted
Tae Gyun Kim@TaeGyun_Kim_SNU
29 Nov 2024
Proteolethargy is a pathogenic mechanism in chronic disease: Cell cell.com/cell/fulltext/S0092…

Proteolethargy is a pathogenic mechanism in chronic disease

Pathogenic signaling leads to reduced mobility of proteins with diverse functions. This proteolethargy, which is due to increased oxidation of cysteine residues, may account for diverse cellular...

cell.com
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Sovanny Taylor (Sophie) retweeted
Stella Hurtley@SMHSci
28 Nov 2024
Identification of a factor that accelerates substrate release from the signal recognition particle | Science science.org/doi/10.1126/scie…

Identification of a factor that accelerates substrate release from the signal recognition particle

The eukaryotic signal recognition particle (SRP) cotranslationally recognizes the first hydrophobic segment of nascent secretory and membrane proteins and delivers them to a receptor at the endopla...

science.org
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Sovanny Taylor (Sophie) retweeted
Molecular Cell@MolecularCell
25 Nov 2024
Online Now: lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing dlvr.it/TGNsHh
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Sovanny Taylor (Sophie) retweeted
Gan Lab@LiGanLab
11 Nov 2024
New finding on APOE today in @CellCellPress: APOE2 and the Christchurch mutation are defective in LDLR binding. Decreased lipidated ApoE-receptor interactions may protect against the pathogenicity of ApoE and its lipid cargoes in lysosomes cell.com/cell/fulltext/S0092…

Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and...

ApoE2 and ApoE Christchurch variants are defective in LDLR binding, thus reducing the uptake of ApoE and associated lipid cargoes. LDLR-mediated internalization and endolysosomal delivery of ApoE...

cell.com
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Sovanny Taylor (Sophie) retweeted
Somnath Mondal@somomsom
22 Oct 2024
We are getting ready for the online symposium with the Biophysical Society. Here is the registration (no fees) link: biophysics.org/upcoming-netw… @BiophysicalSoc
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Sovanny Taylor (Sophie) retweeted
King L Hung@kinglhung
6 Nov 2024
Cancer cells often harbor oncogenes outside chromosomes on extrachromosomal DNA (ecDNA), which is unevenly inherited by dividing cells. Today we report in @Nature that collectives of ecDNAs are inherited together by dividing cancer cells. 1/ nature.com/articles/s41586-0…

Coordinated inheritance of extrachromosomal DNAs in cancer cells

Nature - Cooperative species of extrachromosomal DNAs are coordinately inherited through mitotic co-segregation.

nature.com
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Congrats to @JLeeLab !!! 🎉
Journal of Cell Biology@JCellBiol
14 Oct 2024
Fahim and Marcus et al. @JLeeLab @bcmhouston developed live-cell #microscopy approaches to address whether co-localized enzyme factors are forming biochemically relevant interactions within RNA–protein condensates. hubs.la/Q02TgxV-0 #Biochemistry #RNAbiology
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Sovanny Taylor (Sophie) retweeted
Laurence Seabrook@LJSeabrook
16 Oct 2024
I’m so excited to welcome MrTAC to the world of targeted protein degradation! We created a chemical inducer of arginine methylation that can be used to degrade proteins in lysosomes 💊 So grateful for everyone involved in this project 🥳🥳 nature.com/articles/s41589-0…

Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins

Nature Chemical Biology - Development of a targeted protein degradation platform, methylarginine targeting chimera (MrTAC), enables arginine methylation-driven degradation of intracellular proteins...

nature.com
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Sovanny Taylor (Sophie) retweeted
Jingyi Fei@fei_jingyi
16 Oct 2024
New paper in @ScienceAdvances: We've uncovered the nuclear speckle transcriptome, revealing gene groups with distinct speckle localization properties and that speckles boost splicing for localized transcripts. Thanks to all co-authors! @regevlab science.org/doi/10.1126/scia…
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Sovanny Taylor (Sophie) retweeted
Shahar Sukenik@shaharsu
15 Oct 2024
📢New paper alert!! With @boothbylab @alexholehouse @fried_lab we take a look at how an entire proteome survives desiccation. TLDR: Desiccation tolerance is encoded in specific residues on the protein surface, and occurs primarily in biosynthetic enzymes. shorturl.at/U5VS1
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Sovanny Taylor (Sophie) retweeted
ALS Liga - Ligue SLA@ALSBelgium
14 Oct 2024
Gesteund door ALS Liga fonds A Cure for ALS doctoreerde @BoeynaemsSteven in 2017 @ Lab Neurobiologie KULeuven/VIB @LuVaDeBo. Nu is hij assistant Professor @bcmhouston @texaschildrens waar bij NIH Innovator Award 2,4 M Dollar ontving om eigen lab verder uit te bouwen. Proficiat!
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Sovanny Taylor (Sophie) retweeted
Eva-Maria Schentarra@EvaSchentarra
11 Oct 2024
Do you know what I love most about my PhD @JungmannLab? Actually seeing the things I learned from biology textbooks come to life🪄. Check out this DNA-PAINT image of the Golgi, showing both cis (GM130) and trans (TGN38) faces together with peroxisomes. Happy #FluorescenceFriday😊
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Literally my favorite author with the best books about the human condition
The Nobel Prize
@NobelPrize
10 Oct 2024
BREAKING NEWS The 2024 #NobelPrize in Literature is awarded to the South Korean author Han Kang “for her intense poetic prose that confronts historical traumas and exposes the fragility of human life.”
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Sovanny Taylor (Sophie) retweeted
NIH Common Fund@NIH_CommonFund
8 Oct 2024
Ryan Flynn @raflynn5 of @HSCRB, an #NIHHighRisk Transformative Research Awardee, will explore how and why #RNA and RNA-binding proteins function on cell surfaces. This research could lead to transformative insights in cell #biology and disease mechanisms. hscrb.harvard.edu/news/flynn…

Ryan Flynn Awarded Prestigious NIH Director's Transformative Research Award | HSCRB

hscrb.harvard.edu
HSCRB@HSCRB
8 Oct 2024
Congratulations @raflynn5 for receiving @NIH_CommonFund's Transformative Research Award! #NIHHighRisk hscrb.harvard.edu/news/flynn…
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So happy for @BoeynaemsSteven !!!
NIH Common Fund@NIH_CommonFund
8 Oct 2024
Early-stage investigators proposed #innovative high-impact research ideas for the @NIHDirector’s New Innovator Award. See the projects the awardees will pursue: commonfund.nih.gov/newinnova… #NIHHighRisk
Card with text reads: 2024 NIH Director's New Innovator Awardees. NIH Common Fund logo next to headshot of awardees.

ALT Card with text reads: 2024 NIH Director's New Innovator Awardees. NIH Common Fund logo next to headshot of awardees.
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