Research Article Perceived and Objective Physical Function in 2 United States Population-Based Cohorts of Adults With Systemic Lupus Erythematosus 📖 jrheum.org/cgi/content/full/… @UCSFDOM @JYazdanyMD #Aging #PhysicalFunction #Lupus

>>> Empowering Parkinson’s Disease Management Through Mobile Applications: A Systematic Review and Meta-Analysis |… telehealthandmedicinetoday.c… #mentalhealth #mobilehealthapplications, #Parkinsonsdisease #physicalfunction #mHealth #mobileapps #digitalhealth #eHealth #telehealth

Results of the E-intervention for Protein Intake and Resistance Training to Optimize Function (E-PROOF) study among older cancer survivors geriatriconcology.net/articl… @WilliamDale_MD @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #Elsevier #CancerSurvivorship #GeriatricOncology #PhysicalFunction #RandomizedControlledTrial

New #OpenAccess research from Archives of Rehabilitation Research & Clinical Translation (ARRCT). This study characterizes changes in physical function from acute hospitalization to home health care across different diagnostic categories, highlighting recovery patterns during care transitions. Read the article: archives-rrct.org/article/S2… #ACRM #ARRCT #OpenAccess #RehabilitationResearch #CareTransitions #PhysicalFunction #HomeHealth #HealthServices #ClinicalResearch

Among patients with #Cancer receiving chemotherapy, persistent moderate or severe symptoms, especially deficits in #PhysicalFunction, pain, dyspnea, and appetite, were associated with higher mortality within 180 days. ja.ma/4twZQ4b

If the goal is keeping patients functional and preventing falls, power training is not optional. #MusclePower #FallsPrevention #Healthspan #AgingWell #PhysicalFunction #ACSM2026

Our most recent publication: #Bone, #muscle, and #PhysicalFunction measures in #OlderAdults according to levels of #social #disadvantage: a cross-sectional study: link.springer.com/article/10… @AIMSSresearch @McGill_DOM @RIMUHC1 #Osteosarcopenia

📢 New Study Alert: “Cognitive function, physical function, and mental health in older adults amid reduced primary and specialist healthcare service use during COVID-19: The HUNT Study” by Tanja Louise Ibsen, Geir Selbæk et al. 🔗 Dive into the full article: rdcu.be/eLTY5 #Aging #HealthcareAccess #CognitiveHealth #PhysicalFunction #COVID19 #HUNTStudy #Geriatrics

📢New Open🔓 Access Article Alert One-year concurrent training improves physical performance and handgrip strength in nursing home residents by Duarte Barros & Elisa A. Marques et al. rdcu.be/ezgvl #exercise #longtermcare #PhysicalFunction #pragmatictrial

❗Check Out Our New OA🔓 Paper Growth differentiation factor 15 predicts physical function impairment in Spanish older adults: a real-world prospective study by Karine Ferreira de Campos & Rosario Ortolá et al. rdcu.be/ewS56 #Frailty #PhysicalFunction #agility #mobility

Systematic Review by LS Robertson et al. (@SimonGandevia @martin_heroux @joannadiong @geo_fish) The relation between #proprioceptiveability and #physicalfunction in people with #stroke, #Parkinsonsdisease, and #multiplesclerosis ow.ly/PoHR50WoxAY

Fatigue, physical function, and the context of social vulnerability for older adults with cancer geriatriconcology.net/articl… @NikeshaGilmore @WilliamDale_MD @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #Elsevier #CancerRelatedFatigue #PhysicalFunction #PatientReportedOutcomes #SocialDeterminantsofHealth #SocialVulnerability

Most people when they think of resistance training in terms of the benefits, they usually think bigger muscles and more strength. Yes, it does provide those benefits but in addition it also can contribute to improving functional capacity. Not only this is important in general, but this is especially important in patients undergoing cardiopulmonary rehabilitation since functional capacity is usually compromised. When appropriate, resistance training along with aerobic training can further enhance a patients VO2max and overall quality of life, and most importantly decrease mortality. In a way, the benefits of resistance training further allow for the cardiopulmonary system to work easier. Supporting Research: 1) ncbi.nlm.nih.gov/books/NBK99… 2) doi.org/10.1016/S1836-9553(1… 3) doi.org/10.1093/eurjpc/zwac0… 4) pmc.ncbi.nlm.nih.gov/article… 5) pubmed.ncbi.nlm.nih.gov/1725… #CardiacRehab #HeartHealth #CardiacRecovery #ChronicDiseaseExercise #RehabStrong #ResistanceTraining #StrengthTraining #ExercisePhysiology #FunctionalFitness #MoveToImprove #ClinicalExercisePhysiology #ExerciseIsMedicine #PhysicalFunction #RehabExercise #ExerciseForHealth #CardiacRehabilitation #CancerRehab #CancerRehabilitation #OncoRehab #OncoRehabilitation #MovementIsMedicine #Lifestyle #PhysicalTherapy #PhysicalTherapist #ResistanceTraining #StrengthTraining #MusclePower #Muscle #CardiovascularDisease #ExerciseOncology #Cardiology #Cardiologist #ClinicalExercisePhysiologist #LifestyleMedicine

A new study in @ESC_Journals shows that older patients with #HeartFailure with regular #Exercise habits had a lower risk of #Mortality and better #PhysicalFunction post-hospitalization. Read the study here: ow.ly/e7K350ViXpz Press release here: ow.ly/EL2E50ViXqF

📢New Open🔓 Access Paper Alert Examining the test–retest reliability of commonly used neuromuscular, morphological, and functional measures in aging adults by Gustavo Z. Schaun (@GustavoSchaun) & Cristine L. Alberton et al. rdcu.be/edANK #PhysicalFunction #functionalperformance #measurementprecision #reproducibility #aging

Great review discussing the interplay between sarcopenia and cachexia. Sarcopenia leads to muscle atrophy while cachexia not only leads to muscle loss but weight loss due to potent pro-inflammatory cytokines. Both conditions place many challenges on the individual and both share a common factor involving inflammation and metabolism, even though each condition has its own set of characteristics. Even mitochondrial dysfunction plays a common factor between the conditions. Regardless each condition severely impacts health and overall quality of life. This review goes into great detail about the different therapeutic methods for each condition. Many of the methods hold promise for improving the issues associated with each condition. Even though there are a variety of therapeutic ways of preventing or managing the progressions of these conditions, exercise (specifically resistance training) and nutritional interventions can help. Not only they can help manage the issues, but they can help with prevention altogether. Exercise as a strategy alone represents a promising intervention since it can lessen and even possibly reverse the process of muscle wasting in sarcopenia and cachexia but more research is needed to confirm this. Overall each these conditions are complex and treatment should be comprehensive as much as possible. pubmed.ncbi.nlm.nih.gov/3976… #exerciseismedicine #oncology #exerciseoncology #exercise #exerciseoncology #cancerrehab #cancerrehabilitation #rehabilitation #prehab #prehabilitation #exercisephysiologist #exercisephysiology #exercisetherapy #physicaltherapy #physicaltherapist #clinicalexercisephysiologist #clinicalexercisephysiology #obesity #sarcopenia #sarcopenicobesity #cachexia #cancercachexia #diet #nutrition #malnutrition #lifestyle #prevention #treatment #cancerprevention #cancertreatment #qol #physicalfunction #mortality #anxiety #depression #fatigue #mentalhealth #frailty #physicalactivity #olderadult #cancerresearch #aging #nurse #nursepractioner #physician #oncologist #precisionmedicine #preventionscience #publichealth #health

As many more cancer survivors are living longer these days compared to the past, conditions like sarcopenia have become more prevalent. The interplay issues between cancer and sarcopenia leads to even worse quality of life and health outcomes. Some individuals end up getting sarcopenic obesity as well, usually related to post-effects from the cancer treatment. Cancer survivors living with sarcopenic obesity are at a greater risk of mortality which is why lifestyle interventions like diet and exercise are beyond paramount important for them. It's also another reason why cancer support services can really help and every cancer hospital should have them available. Further investigation is important to establish effective physical rehabilitation programs, including exercise protocols tailored for survivors with different levels of sarcopenia. pubmed.ncbi.nlm.nih.gov/3892… #exerciseismedicine #oncology #exerciseoncology #exercise #exerciseoncology #cancerrehab #cancerrehabilitation #rehabilitation #prehab #prehabilitation #exercisephysiologist #exercisephysiology #physicaltherapy #physicaltherapist #clinicalexercisephysiologist #clinicalexercisephysiology #obesity #sarcopenia #sarcopenicobesity #cachexia #cancercachexia #diet #nutrition #malnutrition #lifestyle #prevention #treatment #cancerprevention #cancertreatment #qol #physicalfunction #mortality #anxiety #depression #fatigue #mentalhealth #frailty #physicalactivity #olderadult #cancerresearch #aging #nurse #nursepractioner #physician #oncologist #precisionmedicine #preventionscience #publichealth #health

Wow! Great study. Due to the complexity of issues related to treatment for cancer survivors, resistance training needs to be tailored appropriately for this population. For instance, symptoms as it relates to treatment affects the individual at different levels. Sometimes the side-effects are mild but other days they are more robust. Depending on the level should determine how the exercise prescription should be scaled for the individual, especially resistance training. This is why autoregulation is important. As shown below, mediators such as physiological strain and psychological distress can impact readiness to change as it relates with receiving cancer treatment. Clinicians should be cognizant of these factors especially when prescribing exercise to their patients especially receiving cancer treatment. In addition, the exercise setting should play a factor as well. For instance, cancer survivors (especially undergoing treatment) should have the option to do an exercise intervention telehealth if they are having to come in-person to participate in a exercise program. Having the patient to leave their home while experiencing cancer related side-effects is a workout in its own. Overall, this paper provides a great framework for clinicians to use when prescribing exercise to their patients living with cancer while undergoing treatment and after treatment. pmc.ncbi.nlm.nih.gov/article… #exerciseismedicine #exercisephysiology #cancer #cancersurvivor #training #exerciseplan #physicalfunction #cancercare #oncology #strength #cancertrials #metastasis #musclemass #autoregulation #exerciseoncology #weighttraining #metastaticcancer #cancerprevention #cancertreatment #prevention #treatment #lifestyle #screening #diagnosis #cancerrisk #obesity #exerciseprescription #incidence #recurrence #mortality #inflammation #immunesystem #cancersurvivorship #acsm #cepa #nsca #evidence #fatigue #pain #lymphadema #sarcopenia #resistancetraining #strengthtraining #mentalhealth #exercisephysiologist #muscle #clinicalexercisephysiology #clinicalexercisephysiologist #implementationscience #exerciseoncologist

#IPOP continue the journey toward establishing core outcomes set for assessing #PhysicalFunction in #Haemophilia care. Apart from #TUG (adults) and #6MWT (children), most performance tests have not been adequately tested for reliability, construct validity, responsiveness.

Slowly research is uncovering the secrets of health. Bulging muscle, muscle strength, and muscle power are 3 variables, all relating to muscle. It seems it's the muscle power. In old age that's lost the first $$$$$$ Muscle Fiber Type and Muscle Power Muscle power is primarily related to type II muscle fibers (also known as fast-twitch fibers). These fibers are specialized for quick, explosive movements and generate greater force and power per unit of time compared to type I fibers (slow-twitch fibers), which are more suited for endurance and sustained contractions. Key Characteristics of Type II Fibers: 1. High Force Production: Type II fibers can produce rapid and forceful contractions. 2. Fast Contraction Speed: They contract faster than type I fibers, making them critical for power-based tasks like jumping or sprinting. 3. Anaerobic Energy: Type II fibers rely more on anaerobic metabolism, allowing for rapid energy production but with less endurance. --- Why People Lose Type II Fibers with Age 1. Selective Atrophy of Type II Fibers Age-related Sarcopenia: Aging preferentially affects type II fibers, causing them to shrink (atrophy) or even be lost entirely, while type I fibers are more preserved. Denervation: As people age, motor neurons that innervate type II fibers die off. Without stimulation, these fibers atrophy or are reinnervated by neurons serving type I fibers, converting them to slower fibers. 2. Reduced Activity Levels Aging individuals often reduce their engagement in high-intensity activities like sprinting or jumping, which are essential for maintaining type II fiber function. Prolonged inactivity leads to deconditioning and loss of fast-twitch fiber recruitment. 3. Hormonal Decline Declining levels of anabolic hormones like testosterone and growth hormone reduce muscle protein synthesis, disproportionately affecting type II fibers. Hormonal changes also impair recovery and regeneration of muscle fibers. 4. Mitochondrial Dysfunction Mitochondria in type II fibers are less efficient than in type I fibers. Aging exacerbates mitochondrial dysfunction, making type II fibers more susceptible to oxidative stress and damage. 5. Decreased Neuromuscular Function Aging leads to a decline in the central and peripheral nervous systems, reducing the ability to generate rapid, powerful muscle contractions. Impaired motor unit firing rates and coordination affect the recruitment of type II fibers during power-based movements. --- Implications The early loss of type II fibers significantly impacts muscle power, which is why older adults struggle with tasks requiring quick or explosive movements, such as standing up quickly or climbing stairs. This decline also contributes to a higher risk of falls and decreased physical functionality. --- How to Counteract This Loss High-Velocity Resistance Training: Exercises that emphasize speed and power (e.g., plyometrics or fast resistance training) can help preserve and even rebuild type II fibers. Regular Physical Activity: Activities like sprinting, jumping, or resistance training help maintain type II fiber recruitment. Nutritional Support: Adequate protein intake and, in some cases, supplementation with creatine or amino acids can support muscle protein synthesis. Hormonal Therapy: In certain cases, addressing hormonal deficiencies (under medical supervision) may help mitigate muscle loss. Focusing on type II fibers through targeted interventions can help preserve muscle power and enhance the quality of life as people age. $$$ Title Powerpenia Should be Considered a Biomarker of Healthy Aging --- Authors Sandro R. Freitas, Carlos Cruz-Montecinos, Sébastien Ratel, Ronei S. Pinto --- Date of Publication 2024 --- DOI 10.1186/s40798-024-00689-6 --- Summary The article proposes the term "powerpenia" to describe the loss of skeletal muscle power due to aging, physical inactivity, or disease. Unlike sarcopenia (focused on muscle mass loss) and dynapenia (focused on strength loss), powerpenia emphasizes the critical role of muscle power—a combination of force and velocity—in maintaining physical functionality, reducing fall risk, and improving quality of life. The concept highlights a gap in current diagnostic and intervention strategies, advocating for targeted approaches to address this decline effectively. --- Main Findings 1. Skeletal Muscle Power as a Marker of Aging Skeletal muscle power declines at a faster rate than muscle strength and mass with aging. Power has a stronger association with fall prevention and physical functionality compared to strength. Studies demonstrate that muscle power is a better predictor of physical performance and mortality in older adults. 2. Limitations of Existing Biomarkers Sarcopenia: Focuses on muscle mass but ignores functional parameters like power. Dynapenia: Encompasses strength and power but is predominantly measured using maximal strength tests (e.g., handgrip), ignoring power. Only 0.9% of studies on dynapenia between 2008 and 2023 directly measured muscle power. 3. Powerpenia as a Proposed Concept Powerpenia differentiates itself by focusing exclusively on skeletal muscle power. The term is proposed to improve clarity and diagnostic accuracy in clinical and research settings. Specific factors, such as velocity-based training, play a unique role in combating power loss, distinct from those influencing muscle strength or mass. 4. Disease and Inactivity Impact Conditions such as type 2 diabetes, sarcopenia, and Parkinson’s disease exacerbate power loss more than strength or mass loss. Physical inactivity is strongly linked to reductions in muscle power, indicating its importance as a sensitive marker for health status. 5. Future Implications The authors advocate for including powerpenia in the broader framework of healthy aging biomarkers alongside sarcopenia and dynapenia. Specific interventions, such as power-focused resistance training, show promise in reversing muscle power decline safely and effectively. --- Recommendations 1. Conceptual Clarity Powerpenia: Define as the specific decline in muscle power, distinguishing it from sarcopenia and dynapenia. Dynapenia: Redefine as exclusively the loss of maximal muscle strength. 2. Training Interventions Power training should focus on high-velocity resistance exercises, as they are more effective for improving muscle power than traditional strength training. Task-specific exercises, like sit-to-stand and fast walking, should be emphasized for older adults to enhance functionality and prevent falls. 3. Research Directions Develop standardized protocols to measure muscle power across age groups and clinical conditions. Investigate powerpenia's impact on diverse populations, including children, to understand its broader implications. Use multicentric and multicultural studies to explore powerpenia in different health contexts and its interaction with non-communicable diseases. --- Conclusions Powerpenia represents a critical advancement in understanding the physical decline associated with aging and disease. Its recognition as a distinct biomarker could revolutionize clinical diagnostics and interventions. By focusing on the unique attributes of muscle power, the concept aims to improve physical functionality, reduce fall risks, and enhance the overall quality of life for aging populations. The adoption of powerpenia may also drive more targeted research and pave the way for innovative therapeutic strategies. --- Key Takeaways Muscle power, not strength or mass, is the most critical determinant of aging-related physical decline. Existing frameworks inadequately address the role of power in healthy aging. Powerpenia could drive targeted interventions like high-velocity power training to improve health outcomes in older adults. --- Hashtags #HealthyAging #MusclePower #Powerpenia #Sarcopenia #Dynapenia #FallPrevention #AgingWell #PhysicalFunction #ResistanceTraining #AgingResearch #NeuromuscularHealth #ActiveAging #ExerciseScience #PublicHealthInnovation