Peptide Reveals Oligomers americanpeptidesociety.org/r… #AlzResearch #AlzSky #MountSinai

Via @TheLancet: Walking 7,000 steps daily may cut #dementia risk by 38 percent and boost overall health, new research finds: hubs.la/Q03PLJy10 #NeuroTwitter @AANMember @DrMelodyDing @BryanDJames @AmalForResearch @DeborahEBarnes @SamGandy @SydneySPH @rushalzheimers

Via @TheLancet: Walking 7,000 steps daily may cut #dementia risk by 38 percent and boost overall health, new research finds: hubs.la/Q03N_xsF0 #NeuroTwitter @AANMember @DrMelodyDing @BryanDJames @AmalForResearch @DeborahEBarnes @SamGandy @SydneySPH @rushalzheimers

Ahhhhh…. Surrounded by the greats at #AAIC25. The only question is who is going to get the Nobel Prize first? (hint, hint, it isn’t going to be me!) #Alzheimers @SamGandy @jmschott @RonPetersenMD

A Good Walk: Eye Movements, Heart Rates, and the Science of Serenity / American Council on Science and Health 
In the stillness of a Japanese observation garden, your eyes slow their darting dance, your heart softens its beat, and your body begins to whisper, "I am safe." A new study finds that this isn't just poetic metaphor-our visual patterns and physiology reveal a deep biological response to designed serenity #DrChuckDinerstein acsh.org/news/2025/05/16/goo… @KarlHerrup @PittADRC @KyotoU_News  @OGR_NagasakiU @ducks4dementia @SamGandy @journal_ad @NYUEnvrStudies @pash22 @gcosmal @jerolmack @Doi_Lab @randalljellis @LukensJohnR @AdrianoAguzzi @DrNeuroChic @AkassoglouLab @sean_fogler @KSPHD @LEAD_Coalition @vertigologist @ISSTD @CAResearch @cptsdfoundation @HanleyCenter @UNC_SOM @densitydesign @VA_PTSD_Info #NeuroscienceofZen #SeikoGoto #EyeMovementDesensitizationReprocessing #EMDR #EnvironmentalSciences #StressReduction #DensityofVisualInformation #DVI

Podcast: Should We End Government Science Funding? A Friendly Debate / American Council on Science and Health 
Nobody denies that science is plagued by an epidemic of fraudulent and politicized research, nor that it wastes billions of taxpayer dollars. But is the problem severe enough to justify completely eliminating public funding for scientific research? Host @camjenglish and co-host #DrChuckDinerstein take a closer look.  
acsh.org/news/2025/04/28/pod… 
@RogerPielkeJr  @SamGandy @OxygenIvan @dr4liberty @IntegralAnswers @DrLizaMD @simonmaechling @TVC09 @Ananyo @Alan0917 @henryimiller @GeoKabat @AgBioWorld @Clive_Bates @JonEntine @kaveh1000 @fake_journals @Meta_Research1 @DavidSanders @LabMuffin @ivanoransky @ancetetere @jaywgooch @randalljellis @RonaldBailey @GregTHR @RobertWager @VayByrne @nickgillespie @agbiotech @CamiDRyan @mattwridley @MiketheScribe @TheSciBabe @prometheusgreen @PaulLeach51 @Clear_Food @BlessingBox4u @30ASeawitch @marcdraco63 @dr_andrealove @centegro @unige_en @sabhlok @CatoHealth @ivanoransky @marcjoffe @Sarah_Evanega #PredatoryPublishing #PaperMills #SellingAuthorships #ScienceIntergity #ProfessorTerenceKealey #WooSukHwang #AnilPotti #TacticalScience

Hearing Loss, Dementia, and a Supreme Court That Might Tune Out Prevention / American Council on Science and Health Imagine discovering that up to one in three dementia cases could be prevented with something as simple as treating hearing loss. As scientists present compelling new data linking hearing loss to cognitive decline, the US Supreme Court is simultaneously considering whether insurers must cover preventive care at all—a collision of science and politics #DrChuckDinerstein 
  acsh.org/news/2025/04/23/hea… @LEAD_Coalition @HLAA @HearingResearch @LeahHoustonMD @PainPtFightBack @dona_jayakody @alzassociation @lewybodyny @DrIanWeissman @AkassoglouLab @KSPHD @ThomasKlineMD @JHSPH_Hearing @VeteransHearing @HearingLossCure @DementiaAllianc @_atanas_ @ErinMPrater @RCICaregiving @RarePOV @theUSAging @RebeccaDRobbins @drseanmullen @sallypipes @AmerGeriatrics @aftab_usa  @pash22 @jlschuster827  @VJDementia @ducks4dementia @DementiaLeague @statnews @JDementiaCare @DementiaFriends @DementiaAllianc @CareberryCo @DementiaLeague @SamGandy @myfacialpain @PublicHealth @GillianHSapia  @plwin49 @HealthcareGlob1 @HHCaregiver @NationsHealth #HearingLoss, #Dementia #PreventiveCare #HealthcarePolicy #USPSTF #HearingAids #Braidwood #CognitiveDecline #ARICNCS #AudiometricTesting #PopulationAttributableFraction #AffordableCareAct #ACA #AppointmentsClauseoftheConstitution #ReligiousFreedomRestorationAct #RFRA

Science Subsidy Trap: Why Public Research Funding Needs to End / American Council on Science and Health 
The U.S. government spends over $160 billion annually on scientific research. This massive expense is marketed to taxpayers as an investment in groundbreaking research that fuels innovation and discovery. In truth, much of the federal science budget is expended on questionable and even fraudulent research. It's time we eliminate it @camjengish acsh.org/news/2025/04/16/sci… @RogerPielkeJr  @SamGandy @OxygenIvan @dr4liberty @IntegralAnswers @DrLizaMD @simonmaechling @TVC09 @Ananyo @Alan0917 @henryimiller @GeoKabat @AgBioWorld @Clive_Bates @JonEntine @kaveh1000 @fake_journals @Meta_Research1 @CamiDRyan @Paul_leach @GregTHR @nickgillespie @DavidSanders @LabMuffin @ivanoransky @marcjoffe @Sarah_Evanega @MiketheScribe @BlessingBox4u @LudgerWess @unige_en @centegro @marcjoffe @marcdraco63 @Avik @_captainscience @30ASeawitch @CatoHealth @life_is_art___ @dr_andrealove @DanaFarber @sabhlok @TheSciBabe @mattwridley @ivanoransky @center4inquiry @RonaldBailey #PredatoryPublishing #PaperMills #SellingAuthorships #ScienceIntergity #ProfessorTerenceKealey #WooSukHwang #AnilPotti #TacticalScience

Just dropped @PGHCircuit 13U Eye Catchers part 2 #PGHDynastyRegionKickOff prepgirlshoops.com/2025/04/1… #SamGandy #KingsleyVara @hkhealy #GeorgiaSmith #BrooklynKeathley #AlaynaTrevino #LaylahPike #HayleePaez #EllieGarza @PGHTexas @PGHArkansas @PrepGirlsHoops

Exited to be in Seoul for #ISMND2024 ! @IcahnMountSinai’s @SinaiBrain Alison Goate, @SamGandy presenting on #Alzheimersdisease today. I’ll be presenting some new data in #Parkinsonsdisease and #microglia!

Presenting virtually, Sam Gandy @SamGandy @IcahnMountSinai discusses ‘Endogenously generated Dutch-type #Abeta #oligomers dysregulate presynaptic neurotransmission in the absence of detectable inflammation’ #ISMND2024

I'm a layperson, but experts such as @SamGandy @SuzanneESchind1 @jasonkarlawish @beyoung40 @JH_Memory_Aging @MichaelSesma @KentSmalley may have helpful responses. I imagine assessment results would be compromised if the person isn't 100% sober. ninds.nih.gov/health-informa…

Scientists @SantPauMemory @IRSantPau @BSC_CNS, led by Dr. Juan Fortea, propose new way of understanding genetics of #Alzheimers, suggest genetics as a cause, not just a risk, for some Alzheimers. 👉 @IcahnMountSinai's Dr.@SamGandy Weighs In @nytimes! nytimes.com/2024/05/06/healt…

For example, different batches of INNOTEST for Ab42 show coefficients of variation from 4-27%. @AlbertoEspay

It's the difference btwn deductive reasoning and inductive reasoning IMO livescience.com/21569-deduct… via @alinabradford & @LaMinda

And much to their disappointment and surprise .

This is correct, Lon. This hypothesis is supported by data from monoclonal antibodies which increase Aβ and lessen decline (despite toxicity of amyloid removal) and secretase inhibitors which decrease Aβ and worsen cognition.

All N terminal Abeta antibodies that made it to P2/3 substantially increased Abeta42, 40 & were nominally associated with relatively better rating scales. You can also wrest P’s <.05 from these. So the hypothesis has been validated, no? Lecanemab good, no? Asking for a friend.

New article from @HastingsCentre , highlighted by Madhav @MadhavThambiset "Don’t Give Symptom-Free People Alzheimer’s Drugs"

It’s time for @US_FDA to halt @CassavaSciences ’ Alzheimer’s clinical trials statnews.com/2023/10/17/its-… via @adamfeuerstein